EMD-19855

Helical reconstruction
2.8 Å
EMD-19855
3D View Gallery
Deposition: 14/03/2024
Map released: 29/05/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19855
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9eoh summary report (pdf.gz) Map and 9eoh FULL report (pdf.gz)
EMICSS annotations (xml)

PHF type tau filament from in vitro V337M mutant

EMD-19855

Helical reconstruction
2.8 Å
EMD-19855
3D View Gallery
Deposition: 14/03/2024
Map released: 29/05/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PHF tau filament from in vitro V337M
Fitted models: 9eoh

Deposition Authors: Qi C, Lovestam S, Scheres SHW , Michel G
Tau filaments with the Alzheimer fold in human MAPT mutants V337M and R406W.
Qi C, Lovestam S, Murzin AG, Peak-Chew S, Franco C , Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B , Scheres SHW , Goedert M
(2025) Nat Struct Mol Biol , 32 , 1297 - 1304
PUBMED: 40044789
DOI: doi:10.1038/s41594-025-01498-5
ISSN: 1545-9985