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EMD-19854

Helical reconstruction
3.0 Å
EMD-19854
3D View Gallery
Deposition: 14/03/2024
Map released: 29/05/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-19854
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 9eog summary report (pdf.gz) Map and 9eog FULL report (pdf.gz)
EMICSS annotations (xml)

PHF type tau filament from R406W mutant

EMD-19854

Helical reconstruction
3.0 Å
EMD-19854
3D View Gallery
Deposition: 14/03/2024
Map released: 29/05/2024
Last modified: 23/07/2025
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Homo sapiens
Sample: PHF tau filament from mutant R406W
Fitted models: 9eog

Deposition Authors: Qi C, Scheres SHW , Michel G
Tau filaments with the Alzheimer fold in human MAPT mutants V337M and R406W.
Qi C, Lovestam S, Murzin AG, Peak-Chew S , Franco C , Bogdani M, Latimer C, Murrell JR, Cullinane PW, Jaunmuktane Z, Bird TD, Ghetti B , Scheres SHW , Goedert M
(2025) Nat Struct Mol Biol , 32 , 1297 - 1304
PUBMED: 40044789
DOI: doi:10.1038/s41594-025-01498-5
ISSN: 1545-9985