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natural_source_ncbi_code:"11678"

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Current Database

  • EMDB [18]

Current status

  • REL [18]

Sample type

  • Complex [18]
  • Protein [18]
  • Ligand [11]
  • DNA [8]
  • Other [5]
  • RNA [5]

Organism

  • Human immunodeficiency virus 1 [18]
  • Synthetic construct [8]
  • Homo sapiens [6]
  • Human immunodeficiency virus 1 [5]
  • Thermotoga maritima [1]

EM Method

  • Single-particle [18]

Resolution

  • ≥ 2Å and < 3Å [2]
  • ≥ 3Å and < 4Å [11]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]
  • ≥ 8Å and < 12Å [1]

Model molecular weight

  • 0-50 kDa [1]
  • 100-250 kDa [15]
  • 1-2 MDa [1]

Release Date

  • 2022 [10]
  • 2021 [5]
  • 2020 [2]
  • 2016 [1]

Author by name

  • Arnold E [9]
  • Das K [8]
  • Herdewijn P [8]
  • Martinez SE [8]
  • Nguyen H [8]
  • Schols D [8]
  • Singh AK [8]
  • Bijnens M [6]
  • De Wijngaert B [6]
  • Pannecouque C [6]
  • Uyttersprot K [6]
  • Chen DH [5]
  • Ha B [5]
  • Jackson LN [5]
  • Larsen KP [5]
  • Puglisi EV [5]
  • Zhang J [5]
  • Bauman JD [3]
  • Bruhn JF [3]
  • Destefano JJ [3]
  • Fu Z [3]
  • Harrison JJEK [3]
  • Lyumkis D [3]
  • Montabana E [3]
  • Passos D [3]
  • Passos DO [3]
  • Ruiz FX [3]
  • Tuberty L [3]
  • Choi J [2]
  • De Jonghe S [2]
  • Gu W [2]
  • Kappel K [2]
  • Barouch-bentov R [1]
  • Belnap DM [1]
  • Boyce M [1]
  • Chen X [1]
  • Duncan JA [1]
  • Duyvesteyn HME [1]
  • Einav S [1]
  • Feng H [1]
  • Fry EE [1]
  • Fusco WG [1]
  • Gonzalez-lopez O [1]
  • Harrison J [1]
  • Hertel-wulff A [1]
  • Hsia Y [1]
  • Kapustina M [1]
  • King NP [1]
  • Kumar S [1]
  • Lemon SM [1]
  • Mcknight KL [1]
  • Mcnamara R [1]
  • Nattermann U [1]
  • Ogohara C [1]
  • Shirasaki T [1]
  • Stuart DI [1]
  • Sundquist WI [1]
  • Votteler J [1]
  • Wang L [1]
  • Xie L [1]
  • Yi S [1]

Author by ORCID

  • Singh AK [8]
  • Arnold E [6]
  • Bijnens M [6]
  • De Wijngaert B [6]
  • Martinez SE [6]
  • Nguyen H [6]
  • Das K [6]
  • Herdewijn P [6]
  • Pannecouque C [6]
  • Ha B [5]
  • Larsen KP [5]
  • Jackson LN [5]
  • Ruiz FX [3]
  • Harrison JJEK [3]
  • Bruhn JF [3]
  • Puglisi EV [3]
  • Chen DH [3]
  • Tuberty L [3]
  • Lyumkis D [3]
  • Destefano JJ [3]
  • Passos DO [3]
  • Arnold E [3]
  • Kappel K [2]
  • Das K [2]
  • Martinez SE [2]
  • Schols D [2]
  • De Jonghe S [2]
  • Gu W [2]
  • Nguyen H [2]
  • Einav S [1]
  • Shirasaki T [1]
  • King NP [1]
  • Mcnamara R [1]
  • Lemon SM [1]
  • Boyce M [1]

Journal

  • PNAS [6]
  • NAT COMMUN [5]
  • SCI ADV [3]
  • J MOL BIOL [2]
  • NATURE [1]
  • PLOS PATHOG [1]

Software

  • RELION [15]
  • CRYOSPARC [3]
  • CISTEM [2]
  • SCIPION [1]
  • WARP [1]

Microscope

  • TFS GLACIOS [9]
  • FEI TITAN KRIOS [8]
  • FEI TECNAI F20 [1]

Electron Source

  • FIELD EMISSION GUN [18]

Film or detector model

  • FEI FALCON III 4K X 4K [9]
  • GATAN K2 SUMMIT 4K X 4K [9]

External links

  • UniProt [18]
  • PDB [17]
  • PDBe-Kb [17]
  • Gene Ontology [15]
  • InterPro [15]
  • Pfam [15]
  • ChEMBL [9]
  • DrugBank [9]
  • ChEBI [7]
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EMD-15234
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Structure of self-assembling engineered protein nanocage EPN fused with hepatitis A pX protein
Release date: Aug. 10, 2022
Resolution: 6.7 Å
EM Method: Single-particle
Fitted PDBs: 8a8n
Q-score: 0.169

Shirasaki T, Feng H, Duyvesteyn HME, Fusco WG, McKnight KL, Xie L, Boyce M, Kumar S, Barouch-Bentov R, Gonzalez-Lopez O, McNamara R, Wang L, Hertel-Wulff A, Chen X, Einav S, Duncan JA, Kapustina M, Fry EE, Stuart DI, Lemon SM

PLoS Pathog (2022) 18 pp. e1010543-e1010543 [ Pubmed: 35969644 DOI: doi:10.1371/journal.ppat.1010543 ]

EMD-25075
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PR-RT portion of HIV-1 Pol
Release date: Aug. 10, 2022
Resolution: 3.74 Å
EM Method: Single-particle

Harrison JJEK, Passos DO, Bruhn JF, Bauman JD, Tuberty L, DeStefano JJ, Ruiz FX, Lyumkis D, Arnold E

Sci Adv (2022) 8 pp. eabn9874-eabn9874 [ DOI: doi:10.1126/sciadv.abn9874 Pubmed: 35857464 ]

EMD-25074
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Cryo-EM Structure of the RT component of the HIV-1 Pol Polyprotein
Release date: July 27, 2022
Resolution: 3.8 Å
EM Method: Single-particle
Fitted PDBs: 7sep
Q-score: 0.346

Harrison JJEK, Passos DO, Bruhn JF, Bauman JD, Tuberty L, DeStefano JJ, Ruiz FX, Lyumkis D, Arnold E

Sci Adv (2022) 8 pp. eabn9874-eabn9874 [ DOI: doi:10.1126/sciadv.abn9874 Pubmed: 35857464 ]

EMD-25165
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Cryo-EM Structure of the PR-RT components of the HIV-1 Pol Polyprotein
Release date: July 27, 2022
Resolution: 8.2 Å
EM Method: Single-particle
Fitted PDBs: 7sjx
Q-score: 0.188

Harrison JJEK, Passos DO, Bruhn JF, Bauman JD, Tuberty L, DeStefano JJ, Ruiz FX, Lyumkis D, Arnold E

Sci Adv (2022) 8 pp. eabn9874-eabn9874 [ DOI: doi:10.1126/sciadv.abn9874 Pubmed: 35857464 ]

EMD-14457
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Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with nevirapine
Release date: July 20, 2022
Resolution: 3.32 Å
EM Method: Single-particle
Fitted PDBs: 7z24
Q-score: 0.494

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K

PNAS (2022) 119 pp. e2203660119-e2203660119 [ Pubmed: 35858448 DOI: doi:10.1073/pnas.2203660119 ]

EMD-14458
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Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with nevirapine
Release date: July 20, 2022
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 7z29
Q-score: 0.463

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K

PNAS (2022) 119 pp. e2203660119-e2203660119 [ Pubmed: 35858448 DOI: doi:10.1073/pnas.2203660119 ]

EMD-14462
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Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine
Release date: July 20, 2022
Resolution: 3.38 Å
EM Method: Single-particle
Fitted PDBs: 7z2d
Q-score: 0.452

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K

PNAS (2022) 119 pp. e2203660119-e2203660119 [ Pubmed: 35858448 DOI: doi:10.1073/pnas.2203660119 ]

EMD-14463
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3D View
Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine
Release date: July 20, 2022
Resolution: 3.45 Å
EM Method: Single-particle
Fitted PDBs: 7z2e
Q-score: 0.448

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K

PNAS (2022) 119 pp. e2203660119-e2203660119 [ Pubmed: 35858448 DOI: doi:10.1073/pnas.2203660119 ]

EMD-14465
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Cryo-EM structure of HIV-1 reverse transcriptase with a DNA aptamer in complex with doravirine
Release date: July 20, 2022
Resolution: 3.65 Å
EM Method: Single-particle
Fitted PDBs: 7z2g
Q-score: 0.466

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K

PNAS (2022) 119 pp. e2203660119-e2203660119 [ Pubmed: 35858448 DOI: doi:10.1073/pnas.2203660119 ]

EMD-14466
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3D View
Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with doravirine
Release date: July 20, 2022
Resolution: 3.58 Å
EM Method: Single-particle
Fitted PDBs: 7z2h
Q-score: 0.384

Singh AK, De Wijngaert B, Bijnens M, Uyttersprot K, Nguyen H, Martinez SE, Schols D, Herdewijn P, Pannecouque C, Arnold E, Das K

PNAS (2022) 119 pp. e2203660119-e2203660119 [ Pubmed: 35858448 DOI: doi:10.1073/pnas.2203660119 ]

Sort by: Download
Showing 1 - 10 of 18. Page 1 of 2
Display:
Statistics
×

Download











































Preview first 10
Download

Filter By

Current Database

  • EMDB [18]

Current status

  • REL [18]

Sample type

  • Complex [18]
  • Protein [18]
  • Ligand [11]
  • DNA [8]
  • Other [5]
  • RNA [5]

Organism

  • Human immunodeficiency virus 1 [18]
  • Synthetic construct [8]
  • Homo sapiens [6]
  • Human immunodeficiency virus 1 [5]
  • Thermotoga maritima [1]

EM Method

  • Single-particle [18]

Resolution

  • ≥ 2Å and < 3Å [2]
  • ≥ 3Å and < 4Å [11]
  • ≥ 4Å and < 5Å [2]
  • ≥ 5Å and < 6Å [1]
  • ≥ 6Å and < 8Å [1]
  • ≥ 8Å and < 12Å [1]

Model molecular weight

  • 0-50 kDa [1]
  • 100-250 kDa [15]
  • 1-2 MDa [1]

Release Date

  • 2022 [10]
  • 2021 [5]
  • 2020 [2]
  • 2016 [1]

Author by name

  • Arnold E [9]
  • Das K [8]
  • Herdewijn P [8]
  • Martinez SE [8]
  • Nguyen H [8]
  • Schols D [8]
  • Singh AK [8]
  • Bijnens M [6]
  • De Wijngaert B [6]
  • Pannecouque C [6]
  • Uyttersprot K [6]
  • Chen DH [5]
  • Ha B [5]
  • Jackson LN [5]
  • Larsen KP [5]
  • Puglisi EV [5]
  • Zhang J [5]
  • Bauman JD [3]
  • Bruhn JF [3]
  • Destefano JJ [3]
  • Fu Z [3]
  • Harrison JJEK [3]
  • Lyumkis D [3]
  • Montabana E [3]
  • Passos D [3]
  • Passos DO [3]
  • Ruiz FX [3]
  • Tuberty L [3]
  • Choi J [2]
  • De Jonghe S [2]
  • Gu W [2]
  • Kappel K [2]
  • Barouch-bentov R [1]
  • Belnap DM [1]
  • Boyce M [1]
  • Chen X [1]
  • Duncan JA [1]
  • Duyvesteyn HME [1]
  • Einav S [1]
  • Feng H [1]
  • Fry EE [1]
  • Fusco WG [1]
  • Gonzalez-lopez O [1]
  • Harrison J [1]
  • Hertel-wulff A [1]
  • Hsia Y [1]
  • Kapustina M [1]
  • King NP [1]
  • Kumar S [1]
  • Lemon SM [1]
  • Mcknight KL [1]
  • Mcnamara R [1]
  • Nattermann U [1]
  • Ogohara C [1]
  • Shirasaki T [1]
  • Stuart DI [1]
  • Sundquist WI [1]
  • Votteler J [1]
  • Wang L [1]
  • Xie L [1]
  • Yi S [1]

Author by ORCID

  • Singh AK [8]
  • Arnold E [6]
  • Bijnens M [6]
  • De Wijngaert B [6]
  • Martinez SE [6]
  • Nguyen H [6]
  • Das K [6]
  • Herdewijn P [6]
  • Pannecouque C [6]
  • Ha B [5]
  • Larsen KP [5]
  • Jackson LN [5]
  • Ruiz FX [3]
  • Harrison JJEK [3]
  • Bruhn JF [3]
  • Puglisi EV [3]
  • Chen DH [3]
  • Tuberty L [3]
  • Lyumkis D [3]
  • Destefano JJ [3]
  • Passos DO [3]
  • Arnold E [3]
  • Kappel K [2]
  • Das K [2]
  • Martinez SE [2]
  • Schols D [2]
  • De Jonghe S [2]
  • Gu W [2]
  • Nguyen H [2]
  • Einav S [1]
  • Shirasaki T [1]
  • King NP [1]
  • Mcnamara R [1]
  • Lemon SM [1]
  • Boyce M [1]

Journal

  • PNAS [6]
  • NAT COMMUN [5]
  • SCI ADV [3]
  • J MOL BIOL [2]
  • NATURE [1]
  • PLOS PATHOG [1]

Software

  • RELION [15]
  • CRYOSPARC [3]
  • CISTEM [2]
  • SCIPION [1]
  • WARP [1]

Microscope

  • TFS GLACIOS [9]
  • FEI TITAN KRIOS [8]
  • FEI TECNAI F20 [1]

Electron Source

  • FIELD EMISSION GUN [18]

Film or detector model

  • FEI FALCON III 4K X 4K [9]
  • GATAN K2 SUMMIT 4K X 4K [9]

External links

  • UniProt [18]
  • PDB [17]
  • PDBe-Kb [17]
  • Gene Ontology [15]
  • InterPro [15]
  • Pfam [15]
  • ChEMBL [9]
  • DrugBank [9]
  • ChEBI [7]