EMD-14463

Single-particle
3.45 Å
EMD-14463
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Deposition: 26/02/2022
Map released: 20/07/2022
Last modified: 03/08/2022
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EMD-14463
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Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine

EMD-14463

Single-particle
3.45 Å
EMD-14463
3D View Gallery
Deposition: 26/02/2022
Map released: 20/07/2022
Last modified: 03/08/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Human immunodeficiency virus type 1 BH10, synthetic construct
Sample: NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with rilpivirine
Fitted models: 7z2e

Deposition Authors: Singh AK , Das K
Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
Singh AK , De Wijngaert B , Bijnens M, Uyttersprot K, Nguyen H , Martinez SE, Schols D , Herdewijn P , Pannecouque C , Arnold E , Das K
(2022) PNAS , 119 , e2203660119 - e2203660119
PUBMED: 35858448
DOI: doi:10.1073/pnas.2203660119
ISSN: 1091-6490
ASTM: PNASA6