EMD-14458

Single-particle
3.38 Å
EMD-14458
3D View Gallery
Deposition: 26/02/2022
Map released: 20/07/2022
Last modified: 17/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Overview 3D View Sample Experiment Validation Additional data Links

EMD-14458

Archive Files (Depositor)

Primary 3D volume (map.gz) Half-map 1 Half-map 2 (map.gz) Experimental metadata (xml) Experimental metadata (cif.gz)

Validation (wwPDB)

Map-only validation report (pdf.gz) Map-7z29 summary report (pdf.gz) Map-7z29 FULL report (pdf.gz)

EMDB Annotations

EMICSS entry mapping (xml)

EMDB Files

VA raw map (map) VA resolution mask (mrc)

Cryo-EM structure of NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with nevirapine

EMD-14458

Single-particle
3.38 Å
EMD-14458
3D View Gallery
Deposition: 26/02/2022
Map released: 20/07/2022
Last modified: 17/07/2024
Overview 3D View Sample Experiment Validation Additional data Links
Sample Organism: Human immunodeficiency virus type 1 BH10, synthetic construct
Sample: NNRTI resistant M184I/E138K mutant HIV-1 reverse transcriptase with a DNA aptamer in complex with nevirapine
Fitted models: 7z29

Deposition Authors: Singh AK , Das K
Cryo-EM structures of wild-type and E138K/M184I mutant HIV-1 RT/DNA complexed with inhibitors doravirine and rilpivirine.
Singh AK , De Wijngaert B , Bijnens M, Uyttersprot K, Nguyen H , Martinez SE, Schols D , Herdewijn P, Pannecouque C , Arnold E , Das K
(2022) PNAS , 119 , e2203660119 - e2203660119
PUBMED: 35858448
DOI: doi:10.1073/pnas.2203660119
ISSN: 1091-6490
ASTM: PNASA6
Grant Support: