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CHEBI:35501 - triazolobenzodiazepine
| ChEBI ID | CHEBI:35501 |
| ChEBI Name | triazolobenzodiazepine |
| Stars | |
| Definition | Any organic heterotricyclic compound that is any benzodiazepine which is ortho-fused with a triazole. |
| Last Modified | 24 June 2024 |
| Submitter | Kirill Degtyarenko |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| triazolobenzodiazepine (CHEBI:35501) is a benzodiazepine (CHEBI:22720) |
| triazolobenzodiazepine (CHEBI:35501) is a organic heterotricyclic compound (CHEBI:26979) |
| Incoming Relation(s) |
| 4-Hydroxy-estazolam (CHEBI:178137) is a triazolobenzodiazepine (CHEBI:35501) |
| 4-Hydroxyalprazolam (CHEBI:183714) is a triazolobenzodiazepine (CHEBI:35501) |
| 4-hydroxytriazolam (CHEBI:169925) is a triazolobenzodiazepine (CHEBI:35501) |
| adinazolam (CHEBI:251412) is a triazolobenzodiazepine (CHEBI:35501) |
| alpha-Hydroxyalprazolam (CHEBI:192657) is a triazolobenzodiazepine (CHEBI:35501) |
| alpha-Hydroxytriazolam (CHEBI:166535) is a triazolobenzodiazepine (CHEBI:35501) |
| alprazolam (CHEBI:2611) is a triazolobenzodiazepine (CHEBI:35501) |
| estazolam (CHEBI:4858) is a triazolobenzodiazepine (CHEBI:35501) |
| molibresib (CHEBI:95082) is a triazolobenzodiazepine (CHEBI:35501) |
| triazolam (CHEBI:9674) is a triazolobenzodiazepine (CHEBI:35501) |
| Synonym | Source |
|---|---|
| triazolobenzodiazepines | ChEBI |