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CHEBI:178137 - 4-Hydroxy-estazolam

ChEBI IDCHEBI:178137
ChEBI Name4-Hydroxy-estazolam
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC16H11ClN4O
Net Charge0
Average Mass310.744
Monoisotopic Mass310.06214
SMILESOC1N=C(c2ccccc2)c2cc(Cl)ccc2-n2cnnc21
InChIInChI=1S/C16H11ClN4O/c17-11-6-7-13-12(8-11)14(10-4-2-1-3-5-10)19-16(22)15-20-18-9-21(13)15/h1-9,16,22H
InChIKeyLJIJJCXFWLORDQ-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Arisaema erubescens (ncbitaxon:228806) bulb (BTO:0000159) MetaboLights (MTBLS2858)
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
4-Hydroxy-estazolam (CHEBI:178137) is a triazolobenzodiazepine (CHEBI:35501)
IUPAC Name 
8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-ol
Manual XrefsDatabases
9841473ChemSpider
HMDB0060764HMDB