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CHEBI:9674 - triazolam
| Formula | C17H12Cl2N4 |
| Net Charge | 0 |
| Average Mass | 343.217 |
| Monoisotopic Mass | 342.04390 |
| SMILES | Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2 |
| InChI | InChI=1S/C17H12Cl2N4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3 |
| InChIKey | JOFWLTCLBGQGBO-UHFFFAOYSA-N |
| Wikipedia |
|---|
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| triazolam (CHEBI:9674) has role sedative (CHEBI:35717) |
| triazolam (CHEBI:9674) is a triazolobenzodiazepine (CHEBI:35501) |
| IUPAC Name |
|---|
| 8-chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine |
| Synonym | Source |
|---|---|
| Halcion | ChemIDplus |
| Registry Numbers | Sources |
|---|---|
| Beilstein:1226643 | Beilstein |
| CAS:28911-01-5 | ChemIDplus |