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CHEBI:251412 - adinazolam
| Formula | C19H18ClN5 |
| Net Charge | 0 |
| Average Mass | 351.841 |
| Monoisotopic Mass | 351.12507 |
| SMILES | CN(C)Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2 |
| InChI | InChI=1S/C19H18ClN5/c1-24(2)12-18-23-22-17-11-21-19(13-6-4-3-5-7-13)15-10-14(20)8-9-16(15)25(17)18/h3-10H,11-12H2,1-2H3 |
| InChIKey | GJSLOMWRLALDCT-UHFFFAOYSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | anxiolytic drug Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. anticonvulsant A drug used to prevent seizures or reduce their severity. sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| adinazolam (CHEBI:251412) has role anticonvulsant (CHEBI:35623) |
| adinazolam (CHEBI:251412) has role antidepressant (CHEBI:35469) |
| adinazolam (CHEBI:251412) has role anxiolytic drug (CHEBI:35474) |
| adinazolam (CHEBI:251412) has role sedative (CHEBI:35717) |
| adinazolam (CHEBI:251412) is a triazolobenzodiazepine (CHEBI:35501) |
| IUPAC Name |
|---|
| 1-(8-chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl)-N,N-dimethylmethanamine |
| INNs | Source |
|---|---|
| adinazolam | KEGG DRUG |
| adinazolamum | DrugBank |
| Synonym | Source |
|---|---|
| 8-Chloro-1-((dimethylamino)methyl)-6-phenyl-4H-s-triazolo(4,3-a)(1,4)benzodiazepine | ChemIDplus |