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CHEBI:183714 - 4-Hydroxyalprazolam
| Formula | C17H13ClN4O |
| Net Charge | 0 |
| Average Mass | 324.771 |
| Monoisotopic Mass | 324.07779 |
| SMILES | Cc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1)=NC2O |
| InChI | InChI=1S/C17H13ClN4O/c1-10-20-21-16-17(23)19-15(11-5-3-2-4-6-11)13-9-12(18)7-8-14(13)22(10)16/h2-9,17,23H,1H3 |
| InChIKey | CEYGCFLPQFNPST-UHFFFAOYSA-N |
| Species of Metabolite | Component | Source | Comments |
|---|---|---|---|
| Bombus terrestris (ncbitaxon:30195) | |||
| brain (BTO:0000142) | MetaboLights (MTBLS3637) | ||
| hemolymph (BTO:0000572) | MetaboLights (MTBLS3637) | ||
| hindgut (BTO:0000510) | MetaboLights (MTBLS3637) |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Application: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| 4-Hydroxyalprazolam (CHEBI:183714) is a triazolobenzodiazepine (CHEBI:35501) |
| IUPAC Name |
|---|
| 8-chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-ol |
| Manual Xrefs | Databases |
|---|---|
| 158315 | ChemSpider |
| HMDB0060554 | HMDB |
| Registry Numbers | Sources |
|---|---|
| CAS:30896-57-2 | ChemIDplus |