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CHEBI:756703 - balovaptan
| Formula | C22H24ClN5O |
| Net Charge | 0 |
| Average Mass | 409.921 |
| Monoisotopic Mass | 409.16694 |
| SMILES | CN1Cc2cc(Cl)ccc2-n2c(nnc2[C@H]2CC[C@H](Oc3ccccn3)CC2)C1 |
| InChI | InChI=1S/C22H24ClN5O/c1-27-13-16-12-17(23)7-10-19(16)28-20(14-27)25-26-22(28)15-5-8-18(9-6-15)29-21-4-2-3-11-24-21/h2-4,7,10-12,15,18H,5-6,8-9,13-14H2,1H3/t15-,18- |
| InChIKey | GMPZPHGHNDMRKL-RZDIXWSQSA-N |
| Roles Classification |
|---|
| Biological Role: | GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| Applications: | antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. GABA modulator A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
| ChEBI Ontology |
|---|
| Outgoing Relation(s) |
| balovaptan (CHEBI:756703) has role antidepressant (CHEBI:35469) |
| balovaptan (CHEBI:756703) is a triazolobenzodiazepine (CHEBI:35501) |
| INN | Source |
|---|---|
| balovaptan | WHO MedNet |
| Synonyms | Source |
|---|---|
| RG-7314 | ChEMBL |
| RG7314 | ChEMBL |
| RO-5285119 | ChEMBL |
| RO5285119 | ChEMBL |
| Citations |
|---|