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CHEBI:169925 - 4-hydroxytriazolam

ChEBI IDCHEBI:169925
ChEBI Name4-hydroxytriazolam
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC17H12Cl2N4O
Net Charge0
Average Mass359.216
Monoisotopic Mass358.03882
SMILESCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2O
InChIInChI=1S/C17H12Cl2N4O/c1-9-21-22-16-17(24)20-15(11-4-2-3-5-13(11)19)12-8-10(18)6-7-14(12)23(9)16/h2-8,17,24H,1H3
InChIKeyYUQRFPYHTPARRM-UHFFFAOYSA-N
Species of MetaboliteComponentSourceComments
Malus domestica (ncbitaxon:3750) exocarp (BTO:0000733) MetaboLights (MTBLS2384) Strain: Malus x domestica Borkh. cv. Ruixue
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
4-hydroxytriazolam (CHEBI:169925) is a triazolobenzodiazepine (CHEBI:35501)
IUPAC Name 
8-chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-ol
Manual XrefsDatabases
113711ChemSpider
HMDB0061052HMDB
Registry NumbersSources
CAS:65686-11-5ChemIDplus