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CHEBI:166535 - alpha-Hydroxytriazolam

ChEBI IDCHEBI:166535
ChEBI Namealpha-Hydroxytriazolam
Stars
SubmitterMetaboLights
DownloadsMolfile
FormulaC17H12Cl2N4O
Net Charge0
Average Mass359.216
Monoisotopic Mass358.03882
SMILESOCc1nnc2n1-c1ccc(Cl)cc1C(c1ccccc1Cl)=NC2
InChIInChI=1S/C17H12Cl2N4O/c18-10-5-6-14-12(7-10)17(11-3-1-2-4-13(11)19)20-8-15-21-22-16(9-24)23(14)15/h1-7,24H,8-9H2
InChIKeyBHUYWUDMVCLHND-UHFFFAOYSA-N
Roles Classification
Biological Role:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
Application:
GABA modulator  A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
ChEBI Ontology
Outgoing Relation(s)
alpha-Hydroxytriazolam (CHEBI:166535) is a triazolobenzodiazepine (CHEBI:35501)
IUPAC Name 
[8-chloro-6-(2-chlorophenyl)-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-yl]methanol
Manual XrefsDatabases
HMDB0061053HMDB
1887ChemSpider
Registry NumbersSources
CAS:37115-45-0ChemIDplus