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When to use Ensembl

You can use Ensembl if you:

  • have a gene of interest, and you would like to know if there are homologues in other species, or any sequence variations in the gene
  • would like to know what the sequence is for your gene of interest, and what the sequences of the splice variants (transcripts) are
  • want to explore the region around a gene of interest, and find neighbouring genes
  • want to find sequences that may be involved in gene regulation (open chromatin signatures, transcription factor binding sites, etc.)
  • are interested in how conserved a gene or region is across species
  • want to know a selection of sequence variants that have been associated with a disease, for example, diabetes
  • have questions about a gene, variant, or chromosomal region

Ensembl cannot help you if:

  • want to submit sequence files (see the course on ENA)
  • your species of interest is not a chordate (see a sister project, Ensembl Genomes)