Substrates for peptidase S77.001: prohead peptidase gp21 (bacteriophage T4)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
capsid assembly scaffolding protein	P04534	1-269	peptide-Glu61+Lys-peptide	P	NT	Lys	Ile	Ala	Glu	Lys	Ala	Glu	Glu	Black et al., 1994
capsid assembly scaffolding protein	P04534	1-269	peptide-Glu84+Gln-peptide	P	NT	Lys	Ile	Ala	Glu	Gln	Ala	Ser	Lys	Black et al., 1994
hemoglobin subunit beta	P68871	1-147	peptide-Glu91+Leu-peptide	P	NT	Thr	Leu	Ser	Glu	Leu	His	Cys	Asp	Black et al., 1994
internal protein I	P03718	1-95	peptide-Glu19+Ala-peptide	P	NT	Thr	Ile	Thr	Glu	Ala	Thr	Leu	Thr	Black et al., 1994
internal protein II	P03719	1-100	peptide-Glu10+Ala-peptide	P	NT	Phe	Ile	Ala	Glu	Ala	Arg	Val	Gly	Black et al., 1994
internal protein III	P13302	1-193	peptide-Glu10+Ala-peptide	P	NT	Phe	Ile	Ala	Glu	Ala	Ser	Val	Val	Black et al., 1994
major capsid protein	P04535	1-521	peptide-Glu65+Ala-peptide	P	NT	Phe	Leu	Thr	Glu	Ala	Glu	Ile	Gly	Black et al., 1994
major capsid protein	P04535	1-521	peptide-Glu67+Ile-peptide	P	NT	Thr	Glu	Ala	Glu	Ile	Gly	Gly	Asp	Black et al., 1994
major capsid protein	P04535	1-521	peptide-Glu38+Asn-peptide	P	NT	Lys	Ile	Phe	Glu	Asn	Gln	Glu	Lys	Black et al., 1994
major capsid protein	P04535	1-521	peptide-Glu18+Gly-peptide	P	NT	Pro	Leu	Leu	Glu	Gly	Glu	Gly	Leu	Black et al., 1994
major capsid protein {ECO:0000303\|PubMed:6335532}	P04535	1-521	peptide-Glu65+Ala-peptide	P	NT	Phe	Leu	Thr	Glu	Ala	Glu	Ile	Gly	Jardine et al., 1998
NAD--protein ADP-ribosyltransferase	P12726	1-682	peptide-Glu6+Leu-peptide	P	NT	Leu	Ile	Thr	Glu	Leu	Phe	Asp	Glu	Black et al., 1994
prehead core component PIP	P03720	1-80	peptide-Glu46+Gly-peptide	P	NT	Phe	Leu	Ile	Glu	Gly	Glu	Glu	Pro	Black et al., 1994
prohead assembly protein gp68	P04538	1-141	peptide-Glu16+Ala-peptide	P	NT	Glu	Asn	Val	Glu	Ala	Leu	Ile	Pro	Black et al., 1994
prohead core protein protease	P06807	1-212	peptide-Glu206+Ala-peptide	P	NT	Ala	Leu	Ala	Glu	Ala	Met	Lys	Lys