Substrates for peptidase S49.005: archaean signal peptide peptidase 1

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
alpha-S1-casein P02662 16-214 peptide-Leu124+Glu-peptide N NT Val Pro Gln Leu Glu Ile Val Pro Yokoyama & Matsui, 2005
alpha-S1-casein P02662 16-214 peptide-Asn32+Glu-peptide N Glu Val Leu Asn Glu Asn Leu Leu Yokoyama & Matsui, 2005
alpha-S2-casein P02663 16-222 peptide-Leu114+Tyr-peptide N Leu Gln Tyr Leu Tyr Gln Gly Pro Yokoyama & Matsui, 2005
beta-casein P02666 16-224 peptide-Asn83+Ser-peptide N NT Pro Ile Pro Asn Ser Leu Pro Gln Yokoyama & Matsui, 2005
beta-casein P02666 16-224 peptide-Ser72+Leu-peptide N NT Gln Thr Gln Ser Leu Val Tyr Pro Yokoyama & Matsui, 2005
beta-casein P02666 16-224 peptide-Thr93+Gln-peptide N NT Pro Pro Leu Thr Gln Thr Pro Val Yokoyama & Matsui, 2005
uncharacterized protein PH1511 O59180 1-266 peptide-Leu238+Met-peptide P NT Val Ile Val Leu Met Leu Pro Met Yokoyama & Matsui, 2005