Substrates for peptidase S46.002: dipeptidyl-peptidase 11 (Porphyromonas gingivalis-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Gly-Asp-Leu-Trp-Ala-Th-Gly-His-Phe-Met-NH2 Gly-Asp+Leu-Trp-Ala-Thr S - - Gly Asp Leu Trp Ala Thr Ohara-Nemoto et al., 2011
Ile-Asp-MCA Ile-Asp+MCA S - - Ile Asp MCA - - - Ohara-Nemoto et al., 2011
Ile-Asp-NHMec Ile-Asp+NHMec S - - Ile Asp AMC - - - Ohara-Nemoto et al., 2011
Leu-Asp-MCA Leu-Asp+MCA S - - Leu Asp MCA - - - Rouf et al., 2013
Leu-Asp-NHMec Leu-Asp+NHMec S - - Leu Asp AMC - - - Ohara-Nemoto et al., 2011
Leu-Glu-MCA Leu-Glu+MCA S - - Leu Glu MCA - - - Ohara-Nemoto et al., 2011
Leu-Glu-NHMec Leu-Glu+NHMec S - - Leu Glu AMC - - - Ohara-Nemoto et al., 2011
Thr-Asp-MCA Thr-Asp+MCA S - - Thr Asp MCA - - - Ohara-Nemoto et al., 2011
Val-Asp-MCA Val-Asp+MCA S - - Val Asp MCA - - - Ohara-Nemoto et al., 2011
[Asp2]-neuromedin-B P08949 47-56 Gly-Asp+Leu-Trp-Ala-Thr-Gly-His-Phe-Met-NH2 N - - Gly Asp Leu Trp Ala Thr Ohara-Nemoto et al., 2011