Substrates for peptidase S41.001: C-terminal processing peptidase-1

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
D1 protein P69560 2-353 peptide-Ala344+Ala-peptide P Leu Asp Leu Ala Ala Ile Glu Ala Satoh, 1998 17760
D1 protein P07753 2-352 peptide-Ala344+Ser-peptide P Leu Asp Leu Ala Ser Thr Asn Ser Satoh, 1998 17759
EDANS-Ala-Ala-Arg-Ala-Ala-Lys((6-aminocaproyl)2-Dabcyl)-Glu-Asn-Tyr-Ala-Leu-Ala-Ala EDANS-Ala-Ala+Arg-Ala-Ala-Lys((6-aminocaproyl)2-Dabcyl)-Glu-Asn-Tyr-Ala-Leu-Ala-Ala S - Ens Ala Ala Arg Ala Ala Lys Keiler & Sauer, 2004
peptidoglycan synthase FtsI P0AD68 1-588 peptide-Val577+Ile-peptide P MU Asn Glu Phe Val Ile Asn Gln Gly Hara et al., 1991
repressor protein CI #105 variant P03034 2-105 peptide-Ala50+Leu-peptide N Gly Val Gly Ala Leu Phe Asn Gly Silber etal, 1991
repressor protein CI #105 variant P03034 2-105 peptide-Ala67+Lys-peptide N Ala Leu Leu Ala Lys Ile Leu Lys Silber etal, 1991
repressor protein CI #105 variant P03034 2-105 peptide-Ala82+Arg-peptide N Pro Ser Ile Ala Arg Glu Ile Tyr Silber etal, 1991
repressor protein CI #105 variant P03034 2-105 peptide-Val92+Ser-peptide N Tyr Glu Ala Val Ser Met Gln Pro Silber etal, 1991
transcription factor p65 Q04206 1-551 peptide-Phe351+Thr-peptide P Pro Tyr Pro Phe Thr Ser Ser Leu Lad et al., 2007