Substrates for peptidase S32.001: equine arteritis virus serine peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu1064+Gly-peptide	P	Met	Val	Phe	Glu	Gly	Leu	Phe	Arg	Snijder et al., 1996	17744
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu1268+Ser-peptide	P	Ser	Asn	Arg	Glu	Ser	Ser	Leu	Ser	Snijder et al., 1996	17745
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu1430+Gly-peptide	P	Tyr	Phe	Leu	Glu	Gly	Gly	Val	Lys	Snijder et al., 1996	17746
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu1677+Gly-peptide	P	Gly	Ser	Tyr	Glu	Gly	Leu	Asp	Gln	Snijder et al., 1996	17748
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu1452+Gly-peptide	P	Ile	Thr	Gln	Glu	Ser	Leu	Thr	Ala	Snijder et al., 1996	17747
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu2370+Ser-peptide	P	Lys	Gln	Tyr	Glu	Ser	Ala	Val	Cys	Van Dinten et al., 1999	17750
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Gln2837+Ser-peptide	P	Trp	Glu	Lys	Gln	Ser	Asn	Lys	Ile	Van Dinten et al., 1999	17749
equine arterivirus ORF1ab polyprotein	P19811	1-3175	peptide-Glu3056+Gly-peptide	P	Tyr	Val	Gln	Glu	Gly	Val	Asp	Ala	Van Dinten et al., 1999	17751
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Gly1286+Gly-peptide	N	Phe	Val	Ser	Gly	Gly	His	Val	Ala	Ziebuhr et al., 2000
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Glu1512+Gly-peptide	P	Ser	Val	Leu	Glu	Gly	Ser	Leu	Arg	Ziebuhr et al., 2000
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Glu1878+Gly-peptide	P	Tyr	Phe	Ala	Glu	Gly	Asn	Leu	Arg	Ziebuhr et al., 2000
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Glu1894+Gly-peptide	P	Met	Thr	Pro	Glu	Gly	Leu	Thr	Ala	Ziebuhr et al., 2000
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Glu2843+Lys-peptide	P	Ser	Ala	Glu	Glu	Lys	Lys	Lys	Cys	Ziebuhr et al., 2000
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Glu3272+Gly-peptide	P	Met	Gly	Leu	Glu	Gly	Thr	Ala	Ser	Ziebuhr et al., 2000
porcine reproductive and respiratory syndrome arterivirus-type cysteine peptidase alpha	Q83017	1-3616	peptide-Glu3494+Gly-peptide	P	Tyr	Phe	His	Glu	Gly	Ile	Arg	Pro	Ziebuhr et al., 2000