Substrates for peptidase S21.001: assemblin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
assemblin P10210 1-635 peptide-Ala247+Ser-peptide P Tyr Leu Gln Ala Ser Glu Lys Phe Darke, 2004 17708
assemblin P10210 1-635 peptide-Ala610+Ser-peptide P Leu Val Asn Ala Ser Ser Ala Ala Darke, 2004 17709
consensus-alanyl bond peptide-Val-Xaa-Ala+Ser-peptide N NPe Val Xaa Ala Ser CPe - - Darke, 2004
consensus-alanyl bond peptide-Leu-Xaa-Ala+Ser-peptide N NPe Leu Xaa Ala Ser CPe - - Darke, 2004
UL26 {ECO:0000313|EMBL:AFI70810.1} Q83417 1-524 peptide-Ala225+Thr-peptide P NT Tyr Leu Gln Ala Thr Met Trp Ala Zühlsdorf et al., 2015