Substrates for peptidase S08.130: MCP-01 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Bz-Phe-Val-Arg-NHPhNO2 Bz-Phe-Val-Arg+NHPhNO2 S Bz Phe Val Arg NAN - - - Chen et al., 2007
collagen alpha-1(I) chain P02453 1-1463 peptide-Phe269+Ser-peptide N His Arg Gly Phe Ser Gly Leu Asp Zhao et al., 2008
collagen alpha-2(I) chain P02465 1-1364 peptide-His510+Ala-peptide N Glu Lys Gly His Ala Gly Leu Ala Zhao et al., 2008
collagen alpha-2(I) chain P02465 1-1364 peptide-Gly638+Leu-peptide N Gly Pro Ser Gly Leu Pro Gly Glu Zhao et al., 2008
Suc-Ala-Ala-Pro-Leu-NHPhNO2 Suc-Ala-Ala-Pro-Leu+NHPhNO2 S Ala Ala Pro Leu NAN - - - Chen et al., 2007
Suc-Ala-Ala-Pro-Phe-NHPhNO2 Suc-Ala-Ala-Pro-Phe+NHPhNO2 S Ala Ala Pro Phe NAN - - - Chen et al., 2007