Substrates for peptidase S01.480: HtrA peptidase (Chlamydia trachomatis-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
beta-casein P02666 1-224 peptide-Pro221+Ile-Ile-Val N Gly Pro Phe Pro Ile Ile Val - Timms et al., 2007
beta-casein P02666 1-224 peptide-Pro211+Val-peptide N Tyr Gln Glu Pro Val Leu Gly Pro Timms et al., 2007
beta-casein P02666 1-224 peptide-Pro96+Val-peptide N Thr Gln Thr Pro Val Val Val Pro Timms et al., 2007
beta-casein P02666 1-224 peptide-Pro90+Pro-peptide N Gln Asn Ile Pro Pro Leu Thr Gln Timms et al., 2007
beta-casein P02666 1-224 peptide-His149+Leu-peptide N Glu Asn Leu His Leu Pro Leu Pro Timms et al., 2007
beta-casein P02666 1-224 peptide-Leu150+Pro-peptide N Asn Leu His Leu Pro Leu Pro Leu Timms et al., 2007
beta-casein P02666 1-224 peptide-Ser111+Lys-peptide N Met Gly Val Ser Lys Val Lys Glu Timms et al., 2007
beta-casein P02666 1-224 peptide-Ile81+Pro-peptide N Pro Gly Pro Ile Pro Asn Ser Leu Timms et al., 2007
beta-casein P02666 1-224 peptide-Ile45+Glu-peptide N Asn Lys Lys Ile Glu Lys Phe Gln Timms et al., 2007
beta-casein P02666 1-224 peptide-Lys47+Phe-peptide N Lys Ile Glu Lys Phe Gln Ser Glu Timms et al., 2007
beta-casein P02666 1-224 peptide-Glu123+Met-peptide N Lys His Lys Glu Met Pro Phe Pro Timms et al., 2007
beta-casein P02666 1-224 peptide-Lys191+Ala-peptide N Val Pro Gln Lys Ala Val Pro Tyr Timms et al., 2007
beta-casein P02666 1-224 peptide-Pro201+Ile-peptide N Arg Asp Met Pro Ile Gln Ala Phe Timms et al., 2007
beta-casein P02666 1-224 peptide-Gln197+Arg-peptide N Pro Tyr Pro Gln Arg Asp Met Pro Timms et al., 2007