Literature for peptidase S01.480: HtrA peptidase (Chlamydia trachomatis-type)

(Topics flags: P Specificity, I Inhibitor, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

2024
1. Phillips,M.J.A., Huston,W.M., McDonagh,A.M. and Rawling,T.
   4-Chloroisocoumarins as Chlamydial Protease Inhibitors and Anti-Chlamydial Agents
   Molecules (2024) 29 PubMed  Europe PubMed DOI  PMC  EPMC
2019
2. Agbowuro,A.A., Hwang,J., Peel,E., Mazraani,R., Springwald,A., Marsh,J.W., McCaughey,L., Gamble,A.B., Huston,W.M. and Tyndall,J.D.A.
   Structure-activity analysis of peptidic Chlamydia HtrA inhibitors
   Bioorg Med Chem (2019) 27, 4185-4199. PubMed  Europe PubMed DOI  I
2018
3. Backert,S., Bernegger,S., Skorko-Glonek,J. and Wessler,S.
   Extracellular HtrA serine proteases: an emerging new strategy in bacterial pathogenesis
   Cell Microbiol (2018) , e12845-e12845. PubMed  Europe PubMed DOI
2015
4. Ong,V.A., Lawrence,A., Timms,P., Vodstrcil,L.A., Tabrizi,S.N., Beagley,K.W., Allan,J.A., Hocking,J.S. and Huston,W.M.
   In vitro susceptibility of recent Chlamydia trachomatis clinical isolates to the CtHtrA inhibitor JO146
   Microbes Infect (2015) 17, 738-744. PubMed  Europe PubMed DOI  U  I
2013
5. Gloeckl,S., Ong,V.A., Patel,P., Tyndall,J.D., Timms,P., Beagley,K.W., Allan,J.A., Armitage,C.W., Turnbull,L., Whitchurch,C.B., Merdanovic,M., Ehrmann,M., Powers,J.C., Oleksyszyn,J., Verdoes,M., Bogyo,M. and Huston,W.M.
   Identification of a serine protease inhibitor which causes inclusion vacuole reduction and is lethal to Chlamydia trachomatis
   Mol Microbiol (2013) 89, 676-689. PubMed  Europe PubMed DOI  I
6. Marsh,J.W., Lott,W.B., Tyndall,J.D. and Huston,W.W.
   Proteolytic activation of Chlamydia trachomatis HTRA is mediated by PDZ1 domain interactions with protease domain loops L3 and LC and beta strand beta5
   Cell Mol Biol Lett (2013) 18, 522-537. PubMed  Europe PubMed DOI
2012
7. Gloeck,S., Tyndall,J.D., Stansfield,S.H., Timms,P. and Huston,W.M.
   The active site residue V266 of chlamydial HtrA is critical for substrate binding during both in vitro and in vivo conditions
   J Mol Microbiol Biotechnol (2012) 22, 10-16. PubMed  Europe PubMed DOI  P
2011
8. Huston,W.M., Tyndall,J.D., Lott,W.B., Stansfield,S.H. and Timms,P.
   Unique residues involved in activation of the multitasking protease/chaperone HtrA from Chlamydia trachomatis
   PLoS ONE (2011) 6, e24547-e24547. PubMed  Europe PubMed DOI  PMC  EPMC
9. Wu,X., Lei,L., Gong,S., Chen,D., Flores,R. and Zhong,G.
   The chlamydial periplasmic stress response serine protease cHtrA is secreted into host cell cytosol
   BMC Microbiol (2011) 11, 87-87. PubMed  Europe PubMed DOI
10. Zhong,G.
    Chlamydia trachomatis secretion of proteases for manipulating host signaling pathways
    Front Microbiol (2011) 2, 14-14. PubMed  Europe PubMed DOI  PMC  EPMC
2007
11. Huston,W.M., Swedberg,J.E., Harris,J.M., Walsh,T.P., Mathews,S.A. and Timms,P.
    The temperature activated HtrA protease from pathogen Chlamydia trachomatis acts as both a chaperone and protease at 37 degrees C
    FEBS Lett (2007) 581, 3382-3386. PubMed  Europe PubMed DOI