Substrates for peptidase S01.458: chymase 1 (Mus musculus-type)

Summary Gene structure Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Ser	Val	Leu	Phe	Ser	Leu	Arg	Met	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Gly	Thr	Pro	Phe	Ser	Leu	Arg	Ala	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Pro	Ser	Leu	Tyr	Ser	Leu	Ser	Arg	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Ile	Val	Arg	Tyr	Ser	Leu	Ala	Gly	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Val	Ala	Met	Phe	Ser	Val	Arg	Val	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Leu	Ala	Asn	Phe	Ser	Val	Arg	Ile	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Val	Val	Arg	Phe	Ser	Val	Ser	Ser	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Val	Ile	Gly	Tyr	Ser	Ala	Arg	Pro	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Val	Thr	Leu	Phe	Ser	Thr	Arg	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Val	Ser	Leu	Phe	Arg	Leu	Gly	Val	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Val	Val	Leu	Phe	Arg	Leu	Ser	Val	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Pro	Val	Leu	Phe	Arg	Val	Arg	Ser	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Gly	Gln	Ile	Phe	Arg	Val	His	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Ala	Thr	Met	Phe	Arg	Val	Glu	His	Andersson etal, 2008
phage display peptide	peptide-Tyr+Glu-peptide	N	NU	Pro	Gly	Gly	Tyr	Glu	Val	Leu	Thr	Andersson etal, 2008
phage display peptide	peptide-Trp+Pro-peptide	N	NU	Arg	Gly	Gln	Trp	Pro	Arg	Thr	Val	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Lys	Ser	Trp	Tyr	Ser	Leu	Ser	Ser	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Trp	Ser	Trp	Phe	Ser	Leu	Ser	Met	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Phe	Arg	Tyr	Phe	Ser	Leu	Gly	Gly	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Trp	Gln	Trp	Tyr	Ser	Leu	Gly	Leu	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Gly	Thr	Trp	Phe	Ser	Leu	Gly	Val	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Gly	Gly	Trp	Tyr	Ser	Val	Ala	Leu	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Met	Thr	Trp	Phe	Ser	Ser	Gln	Val	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Trp	Arg	Phe	Phe	Ser	Asn	Ala	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Gly	Leu	Phe	Phe	Ser	Met	Tyr	Thr	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Val	Val	Trp	Phe	Arg	Ser	Met	Ala	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Pro	Val	Phe	Phe	Arg	Ile	Arg	Gly	Andersson etal, 2008
phage display peptide	peptide-Phe+Arg-peptide	N	NU	Gln	Met	Phe	Phe	Arg	Leu	Ser	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Thr-peptide	N	NU	Thr	Arg	Phe	Phe	Thr	Leu	Gly	His	Andersson etal, 2008
phage display peptide	peptide-Tyr+Thr-peptide	N	NU	Gly	Gly	Phe	Tyr	Thr	Val	Ala	Asn	Andersson etal, 2008
phage display peptide	peptide-Phe+Ala-peptide	N	NU	Trp	Ser	Phe	Phe	Ala	Leu	Ser	Arg	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Leu	Ser	Lys	Phe	Ser	Leu	Ser	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Trp	Arg	Thr	Phe	Ser	Leu	His	His	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Pro	Val	Leu	Tyr	Ser	Leu	Gly	Tyr	Andersson etal, 2008
phage display peptide	peptide-Tyr+Ser-peptide	N	NU	Pro	Gly	Gly	Tyr	Ser	Val	Arg	Val	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Ile	Met	Thr	Phe	Ser	Ala	Gly	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Ile	Val	Arg	Phe	Ser	Ala	Arg	Trp	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Arg	Val	Leu	Phe	Ser	Ala	His	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Thr	Val	Asn	Phe	Ser	Thr	Ser	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Ser-peptide	N	NU	Met	Phe	Arg	Phe	Ser	His	His	His	Andersson etal, 2008
phage display peptide	peptide-Tyr+Arg-peptide	N	NU	Pro	Gly	Gly	Tyr	Arg	Ala	Met	Lys	Andersson etal, 2008
phage display peptide	peptide-Tyr+Arg-peptide	N	NU	Trp	Arg	Thr	Tyr	Arg	Ser	Ala	Val	Andersson etal, 2008
phage display peptide	peptide-Phe+Ala-peptide	N	NU	Gln	Ala	Ser	Phe	Ala	Leu	Gly	His	Andersson etal, 2008
phage display peptide	peptide-Phe+Ala-peptide	N	NU	Ala	Ala	Arg	Phe	Ala	Ala	His	His	Andersson etal, 2008