Substrates for peptidase S01.446: pseutarin C

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
pefachrome FXa			Ac-D-Cha-Gly-Arg+NHPhNO2	S	Ac	CHA	Gly	Arg	NAN	-	-	-	Rosing, 2004
S2222			Bz-Ile-Glu-Gly-Arg+NHPhNO2	S	Ile	Glu	Gly	Arg	NAN	-	-	-	Rosing, 2004
S2237			Bz-Ile-Glu-piperidyl-Gly-Arg+NHPhNO2	S	Glu	Pip	Gly	Arg	NAN	-	-	-	Rosing, 2004
thrombin precursor	P00734	44-622	peptide-Arg271+Thr-peptide	P	Phe	Asn	Pro	Arg	Thr	Phe	Gly	Ser	Rosing, 2004	17685
thrombin precursor	P00734	44-622	peptide-Arg320+Ile-peptide	P	Ile	Asp	Gly	Arg	Ile	Val	Glu	Gly	Rosing, 2004	17686
thrombin precursor	P00735	44-625	peptide-Arg274+Thr-peptide	P	Ile	Glu	Gly	Arg	Thr	Ser	Glu	Asp	Rosing, 2004	17683
thrombin precursor	P00735	44-625	peptide-Arg323+Ile-peptide	P	Ile	Glu	Gly	Arg	Ile	Val	Glu	Gly	Rosing, 2004	17684
thrombin precursor	P00734	44-622	peptide-Arg320+Ile-peptide	P	Ile	Asp	Gly	Arg	Ile	Val	Glu	Gly	Rao & Kini, 2002
thrombin precursor	P00734	44-622	peptide-Arg271+Thr-peptide	P	Phe	Asn	Pro	Arg	Thr	Phe	Gly	Ser	Rao & Kini, 2002