Substrates for peptidase S01.405: kallikrein 1 (Rattus sp.)

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
Abz-Phe-Arg-Ser-Arg-EDDnp			Abz-Phe-Arg+Ser-Arg-EDDnp	S	-	Abz	Phe	Arg	Ser	Arg	EDD	-	Chao, 2004
Bz-Pro-Phe-Arg-NHPhNO2			Bz-Pro-Phe-Arg+NHPhNO2	S	Bz	Pro	Phe	Arg	NAN	-	-	-	Chao, 2004
D-Val-Leu-Arg-NHMec			D-Val-Leu-Arg+NHMec	S	-	DVa	Leu	Arg	AMC	-	-	-	Chao, 2004
D-Val-Leu-Arg-NHPhNO2			D-Val-Leu-Arg+NHPhNO2	S	-	DVa	Leu	Arg	NAN	-	-	-	Chao, 2004
H-kininogen	P08934	19-639	peptide-Arg362+Arg-peptide	P	Ser	Val	Ile	Arg	Arg	Pro	Pro	Gly	Fogaça et al., 2004	17451
H-kininogen	P08934	19-639	peptide-Arg371+Ala-peptide	P	Ser	Pro	Phe	Arg	Ala	Pro	Arg	Val	Fogaça et al., 2004	17452
L-Val-Leu-Arg-NHPhNO2			L-Val-Leu-Arg+NHPhNO2	S	-	Val	Leu	Arg	NAN	-	-	-	Chao, 2004
Pro-Phe-Arg-NHMec			Pro-Phe-Arg+NHMec	S	-	Pro	Phe	Arg	AMC	-	-	-	Moreau et al., 1992
Tos-Arg-OMe (TAME)			Tos-Arg+OMe	S	-	-	Tos	Arg	OMe	-	-	-	Chao, 2004
Z-Phe-Arg-NHMec			Z-Phe-Arg+NHMec	S	-	Z	Phe	Arg	AMC	-	-	-	Moreau et al., 1992