Substrates for peptidase S01.294: HAT-like 3 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Gly-His-Arg-NHPhNO2 Gly-His-Arg+NHPhNO2 S - Gly His Arg NAN - - - Stallmach & Gloor, 2008
Gly-Pro-Lys-NHPhNO2 Gly-Pro-Lys+NHPhNO2 S - Gly Pro Lys NAN - - - Stallmach & Gloor, 2008
heparin-binding growth factor 2 precursor P09038 10-155 peptide-Arg175+Ile-peptide P Phe Phe Leu Arg Ile His Pro Asp Stallmach & Gloor, 2008 21024
heparin-binding growth factor 2 precursor P09038 10-155 peptide-Lys194+Leu-peptide P Pro His Ile Lys Leu Gln Leu Gln Stallmach & Gloor, 2008 21025
heparin-binding growth factor 2 precursor P09038 10-155 peptide-Lys188+Ser-peptide P Val Arg Glu Lys Ser Asp Pro His Stallmach & Gloor, 2008 21026
heparin-binding growth factor 2 precursor P09038 10-155 peptide-Arg249+Ser-peptide P Asn Thr Tyr Arg Ser Arg Lys Tyr Stallmach & Gloor, 2008 21029
heparin-binding growth factor 2 precursor P09038 10-155 peptide-Arg214+Tyr-peptide P Cys Ala Asn Arg Tyr Leu Ala Met Stallmach & Gloor, 2008 21030
Ile-Pro-Arg-NHPhNO2 Ile-Pro-Arg+NHPhNO2 S - Ile Pro Arg NAN - - - Stallmach & Gloor, 2008
neurobin Q1JRP2 1-431 peptide-Lys199+Val-peptide P Arg Gly His Lys Val Ala Gly Gly Stallmach & Gloor, 2008 21023
Pro-Phe-Arg-NHPhNO2 Pro-Phe-Arg+NHPhNO2 S - Pro Phe Arg NAN - - - Stallmach & Gloor, 2008
Val-Gly-Arg-NHPhNO2 Val-Gly-Arg+NHPhNO2 S - Val Gly Arg NAN - - - Stallmach & Gloor, 2008