$VAR1 = undef;

Summary for peptidase S01.294: HAT-like 3 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

 

Names
MEROPS NameHAT-like 3 peptidase
Other namesMername-AA171 peptidase, neurobin, TMPRSS11C (Mus musculus)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(S) >> Family S1 >> Subfamily A >> S01.294
HolotypeHAT-like 3 peptidase (Mus musculus) (peptidase unit: 187-432), MERNUM MER0021882
History Identifier created: MEROPS 6.1 (10 January 2003)
Activity
Catalytic typeSerine
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (6 cleavages)
Activity statushuman: putative
mouse: putative
Other databases PANTHERhttp://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR43957:SF3
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern-/-/-/RKScissile bond-/-/-/- (based on 11 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 3 1 0 0 0 1 1
Pro 1 1 2 0 0 0 2 0
Ala 0 1 0 0 0 1 1 0
Val 1 1 0 0 1 0 0 0
Leu 0 0 1 0 1 1 1 0
Ile 0 1 1 0 1 0 0 0
Met 0 0 0 0 0 0 0 1
Phe 1 1 1 0 0 0 0 0
Tyr 0 0 1 0 1 0 0 1
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 2 0 0 0
Thr 0 1 0 0 0 0 0 0
Cys 1 0 0 0 0 0 0 0
Asn 1 0 1 0 0 0 0 0
Gln 0 0 0 0 0 1 0 1
Asp 0 0 0 0 0 1 0 1
Glu 0 0 1 0 0 0 0 0
Lys 0 0 0 4 0 0 1 0
Arg 1 1 0 7 0 1 0 0
His 0 1 2 0 0 1 0 1
Mouse genetics
Gene symbol Position Megabases Ensembl Entrez gene MGI
Tmprss11c 5:E1 ENSMUSG00000061184 435845 MGI:3521861