Substrates for peptidase S01.282: SplB peptidase (Staphylococcus aureus)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
ac-Val-Glu-Ile-Asp-NHMec			ac-Val-Glu-Ile-Asp+NHMec	S	Val	Glu	Ile	Asp	AMC	-	-	-	Dubin et al., 2008
beta-casein	P02666	16-224	peptide-Gln55+Thr-peptide	N	Glu	Gln	Gln	Gln	Thr	Glu	Asp	Glu	Dubin et al., 2008
beta-casein	P02666	16-224	peptide-Gln71+Ser-peptide	N	Ala	Gln	Thr	Gln	Ser	Leu	Val	Tyr	Dubin et al., 2008
beta-casein	P02666	16-224	peptide-Gln138+Ser-peptide	N	Thr	Glu	Ser	Gln	Ser	Leu	Thr	Leu	Dubin et al., 2008
beta-casein	P02666	16-224	peptide-Gln156+Ser-peptide	N	Pro	Leu	Leu	Gln	Ser	Trp	Met	His	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Val-peptide	S	Trp	Glu	Leu	Gln	Val	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Gly-peptide	S	Trp	Glu	Leu	Gln	Gly	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Ala-peptide	S	Trp	Glu	Leu	Gln	Ala	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Ser-peptide	S	Trp	Glu	Leu	Gln	Ser	Gln	Ser	Xaa	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Glu-peptide	S	Trp	Glu	Leu	Gln	Glu	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Met-peptide	S	Trp	Glu	Leu	Gln	Met	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Met-peptide	S	Val	Glu	Leu	Gln	Met	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Ser-peptide	S	Val	Glu	Leu	Gln	Ser	Gln	Ser	Xaa	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Alapeptide	S	Trp	Val	Leu	Gln	Ala	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Asp+Ala-peptide	S	Trp	Gln	Leu	Asp	Ala	Ser	Gln	Ser	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Serpeptide	S	Val	Val	Leu	Gln	Ser	Gln	Ser	Xaa	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Ser-peptide	S	Ile	Glu	Ser	Gln	Ser	Gln	Ser	Xaa	Dubin et al., 2008
CLiPS synthetic peptide			peptide-Gln+Glu-peptide	S	Trp	Glu	Val	Gln	Glu	Ser	Gln	Ser	Dubin et al., 2008
glutathione S-transferase (GST)�WELQGS�staphostatin A			peptide-Gln+Gly-peptide	S	Trp	Glu	Leu	Gln	Gly	Ser	Xaa	Xaa	Dubin et al., 2008