Literature for peptidase S01.282: SplB peptidase (Staphylococcus aureus)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, I Inhibitor, P Specificity. To select only the references relevant to a single topic, click the link above. See explanation.)

2026

Glinka,F.L., Mehnert,K., Koch,L., Schmoker,O., Steil,L., Hentschker,C., Volker,U., Johannesen,T.B., Bottcher,D., Lammers,M., Broker,B.M. and Bornscheuer,U.T.<br>Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities<br>Chembiochem (2026) 27, e202500816-e202500816. PubMed Europe PubMed DOI PMC EPMC

2025

Glinka,F.L., Schmoker,O., Singh,A.K., Steil,L., Hentschker,C., Volker,U., Bottcher,D., Lammers,M., Cammann,C., Seifert,U., Kruger,E., Naumann,M., Broker,B.M. and Bornscheuer,U.T.<br>Staphylococcal SplA and SplB serine proteases target ubiquitin(-like) specific proteases<br>AMB Express (2025) 15, 32-32. PubMed Europe PubMed DOI PMC EPMC

2021

Dasari,P., Nordengrun,M., Vilhena,C., Steil,L., Abdurrahman,G., Surmann,K., Dhople,V., Lahrberg,J., Bachert,C., Skerka,C., Volker,U., Broker,B.M. and Zipfel,P.F.<br>The protease SplB of Staphylococcus aureus targets host complement components and inhibits complement-mediated bacterial opsonophagocytosis<br>J Bacteriol (2021) , JB0018421-JB0018421. PubMed Europe PubMed DOI

2017

Stentzel,S., Teufelberger,A., Nordengrun,M., Kolata,J., Schmidt,F., van Crombruggen,K., Michalik,S., Kumpfmuller,J., Tischer,S., Schweder,T., Hecker,M., Engelmann,S., Volker,U., Krysko,O., Bachert,C. and Broker,B.M.<br>Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus<br>J Allergy Clin Immunol (2017) 139, 492-500. PubMed Europe PubMed DOI

2016

Paharik,A.E., Salgado-Pabon,W., Meyerholz,D.K., White,M.J., Schlievert,P.M. and Horswill,A.R.<br>The Spl serine proteases modulate Staphylococcus aureus protein production and virulence in a rabbit model of pneumonia<br>mSphere (2016) 1 PubMed Europe PubMed DOI

2014

Pustelny,K., Stach,N., Wladyka,B., Dubin,A. and Dubin,G.<br>Evaluation of P1' substrate specificity of staphylococcal SplB protease<br>Acta Biochim Pol (2014) 61, 149-152. PubMed Europe PubMed A P

2012

Ewa,B., Maciej,W., Marcin,S., Grzegorz,D., Michal,Z., Jan,P. and Jozef,O.<br>The development of first Staphylococcus aureus SplB protease inhibitors: phosphonic analogues of glutamine<br>Bioorg Med Chem Lett (2012) 22, 5574-5578. PubMed Europe PubMed DOI I

2008

Dubin,G., Stec-Niemczyk,J., Kisielewska,M., Pustelny,K., Popowicz,G.M., Bista,M., Kantyka,T., Boulware,K.T., Stennicke,H.R., Czarna,A., Phopaisarn,M., Daugherty,P.S., Thogersen,I.B., Enghild,J.J., Thornberry,N., Dubin,A. and Potempa,J.<br>Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln<br>J Mol Biol (2008) 379, 343-356. PubMed Europe PubMed DOI S

2006

[YEAR:13-2-2006]Popowicz,G.M., Dubin,G., Stec-Niemczyk,J., Czarny,A., Dubin,A., Potempa,J. and Holak,T.A.<br>Functional and structural characterization of Spl proteases from Staphylococcus aureus<br>J Mol Biol (13-2-2006) 358, 270-279. PubMed Europe PubMed DOI S

2001

Reed,S.B., Wesson,C.A., Liou,L.E., Trumble,W.R., Schlievert,P.M., Bohach,G.A. and Bayles,K.W.<br>Molecular characterization of a novel Staphylococcus aureus serine protease operon<br>Infect Immun (2001) 69, 1521-1527. PubMed Europe PubMed DOI PMC EPMC