Literature for peptidase S01.282: SplB peptidase (Staphylococcus aureus)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: S Structure, A Assay, I Inhibitor, P Specificity. To select only the references relevant to a single topic, click the link above. See explanation.)

    2026
  1. Glinka,F.L., Mehnert,K., Koch,L., Schmoker,O., Steil,L., Hentschker,C., Volker,U., Johannesen,T.B., Bottcher,D., Lammers,M., Broker,B.M. and Bornscheuer,U.T.
    Staphylococcal SplA and SplB Serine Protease Allelic Variants Exhibit Different Substrate Specificities
    Chembiochem (2026) 27, e202500816-e202500816. PubMed  Europe PubMed DOI  PMC  EPMC
  2. 2025
  3. Glinka,F.L., Schmoker,O., Singh,A.K., Steil,L., Hentschker,C., Volker,U., Bottcher,D., Lammers,M., Cammann,C., Seifert,U., Kruger,E., Naumann,M., Broker,B.M. and Bornscheuer,U.T.
    Staphylococcal SplA and SplB serine proteases target ubiquitin(-like) specific proteases
    AMB Express (2025) 15, 32-32. PubMed  Europe PubMed DOI  PMC  EPMC
  4. 2021
  5. Dasari,P., Nordengrun,M., Vilhena,C., Steil,L., Abdurrahman,G., Surmann,K., Dhople,V., Lahrberg,J., Bachert,C., Skerka,C., Volker,U., Broker,B.M. and Zipfel,P.F.
    The protease SplB of Staphylococcus aureus targets host complement components and inhibits complement-mediated bacterial opsonophagocytosis
    J Bacteriol (2021) , JB0018421-JB0018421. PubMed  Europe PubMed DOI
  6. 2017
  7. Stentzel,S., Teufelberger,A., Nordengrun,M., Kolata,J., Schmidt,F., van Crombruggen,K., Michalik,S., Kumpfmuller,J., Tischer,S., Schweder,T., Hecker,M., Engelmann,S., Volker,U., Krysko,O., Bachert,C. and Broker,B.M.
    Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus
    J Allergy Clin Immunol (2017) 139, 492-500. PubMed  Europe PubMed DOI
  8. 2016
  9. Paharik,A.E., Salgado-Pabon,W., Meyerholz,D.K., White,M.J., Schlievert,P.M. and Horswill,A.R.
    The Spl serine proteases modulate Staphylococcus aureus protein production and virulence in a rabbit model of pneumonia
    mSphere (2016) 1 PubMed  Europe PubMed DOI
  10. 2014
  11. Pustelny,K., Stach,N., Wladyka,B., Dubin,A. and Dubin,G.
    Evaluation of P1' substrate specificity of staphylococcal SplB protease
    Acta Biochim Pol (2014) 61, 149-152. PubMed  Europe PubMed  A  P
  12. 2012
  13. Ewa,B., Maciej,W., Marcin,S., Grzegorz,D., Michal,Z., Jan,P. and Jozef,O.
    The development of first Staphylococcus aureus SplB protease inhibitors: phosphonic analogues of glutamine
    Bioorg Med Chem Lett (2012) 22, 5574-5578. PubMed  Europe PubMed DOI  I
  14. 2008
  15. Dubin,G., Stec-Niemczyk,J., Kisielewska,M., Pustelny,K., Popowicz,G.M., Bista,M., Kantyka,T., Boulware,K.T., Stennicke,H.R., Czarna,A., Phopaisarn,M., Daugherty,P.S., Thogersen,I.B., Enghild,J.J., Thornberry,N., Dubin,A. and Potempa,J.
    Enzymatic activity of the Staphylococcus aureus SplB serine protease is induced by substrates containing the sequence Trp-Glu-Leu-Gln
    J Mol Biol (2008) 379, 343-356. PubMed  Europe PubMed DOI  S
  16. 2006
  17. [YEAR:13-2-2006]Popowicz,G.M., Dubin,G., Stec-Niemczyk,J., Czarny,A., Dubin,A., Potempa,J. and Holak,T.A.
    Functional and structural characterization of Spl proteases from Staphylococcus aureus
    J Mol Biol (13-2-2006) 358, 270-279. PubMed  Europe PubMed DOI  S
  18. 2001
  19. Reed,S.B., Wesson,C.A., Liou,L.E., Trumble,W.R., Schlievert,P.M., Bohach,G.A. and Bayles,K.W.
    Molecular characterization of a novel Staphylococcus aureus serine protease operon
    Infect Immun (2001) 69, 1521-1527. PubMed  Europe PubMed DOI  PMC  EPMC