Substrates for peptidase S01.273: DegP peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Abz-Ala-Gln-Arg-Val-Ala-Phe-Tyr(NO)2			Abz-Ala-Gln-Arg-Val+Ala-Phe-Tyr(NO)2	S	Ala	Gln	Arg	Val	Ala	Tyr	TyN	-	Bernegger et al., 2020
Asp-Pro-Met-Phe-Lys-Leu-Val-NHPhNO2			Asp-Pro-Met-Phe-Lys-Leu-Val+NHPhNO2	S	Phe	Lys	Leu	Val	NAN	-	-	-	Hauske et al., 2009
DegP peptidase	P0C0V0	27-474	peptide-Cys95+Gln-peptide	P	Ser	Pro	Phe	Cys	Gln	Gly	Gly	Gln	Jomaa et al., 2009
DegP peptidase	P0C0V0	27-474	peptide-Gln108+Lys-peptide	P	Gly	Gln	Gln	Gln	Lys	Phe	Met	Ala	Jomaa et al., 2009
isoleucyl bond			peptide-Ile+peptide	N	-	-	NPe	Ile	CPe	-	-	-	Kolmar, 2004
Pro-Val-Phe-Asn-Thr-Leu-Pro-Met-Met-Gly-Lys-Ala-Ser-Pro-Val-NHPhNO2			Pro-Val-Phe-Asn-Thr-Leu-Pro-Met-Met-Gly-Lys-Ala-Ser-Pro-Val+NHPhNO2	S	Ala	Ser	Pro	Val	NAN	-	-	-	Hauske et al., 2009
repressor protein CI	P03034	1-237	peptide-Val37+Ala-peptide	N	Gln	Glu	Ser	Val	Ala	Asp	Lys	Met	Kolmar et al., 1996
repressor protein CI	P03034	1-237	peptide-Val72+Ser-peptide	N	Ile	Leu	Lys	Val	Ser	Val	Glu	Glu	Kolmar et al., 1996
repressor protein CI	P03034	1-237	peptide-Ile85+Tyr-peptide	N	Ala	Arg	Glu	Ile	Tyr	Glu	Met	Tyr	Kolmar et al., 1996
repressor protein CI	P03034	1-237	peptide-Val92+Ser-peptide	N	Tyr	Glu	Ala	Val	Ser	Met	Gln	Pro	Kolmar et al., 1996
Ser-Pro-Met-Phe-Lys-Gly-Val-NHPhNO2			Ser-Pro-Met-Phe-Lys-Gly-Val+NHPhNO2	S	Phe	Lys	Gly	Val	NAN	-	-	-	Hauske et al., 2009
transcriptional repressor arc	P03050	1-53	peptide-Val22+Arg-peptide	N	Leu	Asp	Leu	Val	Arg	Lys	Val	Ala	Kolmar et al., 1996
transcriptional repressor arc	P03050	1-53	peptide-Val25+Ala-peptide	N	Val	Arg	Lys	Val	Ala	Glu	Glu	Asn	Kolmar et al., 1996
transcriptional repressor arc	P03050	1-53	peptide-Val41+Met-peptide	N	Tyr	Gln	Arg	Val	Met	Glu	Ser	Phe	Kolmar et al., 1996
Val-Phe-Asn-Thr-Leu-Pro-Met-Met-Gly-Lys-Ala-Ser-Pro-Val-NHPhNO2			Val-Phe-Asn-Thr-Leu-Pro-Met-Met-Gly-Lys-Ala-Ser-Pro-Val-NHPhNO2	S	Ala	Ser	Pro	Val	NAN	-	-	-	Hauske et al., 2009
valyl bond			peptide-Val+peptide	N	-	-	NPe	Val	CPe	-	-	-	Kolmar, 2004