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Literature for peptidase S01.273: DegP peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Ludwig,K. and Heidorn-Czarna,M.
    Mitochondrial Proteases and Their Roles in Mitophagy in Plants, Animals, and Yeast
    Plant Cell Physiol PubMed  Europe PubMed DOI  V
    2. 2024
  2. Chen,M., Shang,Y., Cui,W., Wang,X., Zhu,J., Dong,H., Wang,H., Su,T., Wang,W., Zhang,K., Li,B., Xu,S., Hu,W., Zhang,F. and Gu,L.
    Molecular mechanism of proteolytic cleavage-dependent activation of CadC-mediated response to acid in E. coli
    Commun Biol7, 1335-1335. PubMed  Europe PubMed DOI
  3. Harkness,R.W., Zhao,H., Toyama,Y., Schuck,P. and Kay,L.E.
    Exploring Host-Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR
    J Am Chem Soc146, 8242-8259. PubMed  Europe PubMed DOI
    4. 2023
  4. Jeong,B., Jang,H.A., Lee,J., Bae,H.R. and Kim,J.K.
    Proteolytic Activity of DegP Is Required for the Burkholderia Symbiont To Persist in Its Host Bean Bug
    Microbiol Spectr11, e0433022-e0433022. PubMed  Europe PubMed DOI
  5. Zhang,X., Lin,Y., Xu,X., Wen,S., Wang,Z., Gu,J., He,Q. and Cai,X.
    HtrA is involved in stress response and adhesion in Glaesserella parasuis serovar 5 strain Nagasaki
    Vet Microbiol282, 109748-109748. PubMed  Europe PubMed DOI
    6. 2022
  6. Zhang,L., Zhao,F., Xu,H., Chen,Y., Qi,C. and Liu,J.
    HtrA of Actinobacillus pleuropneumoniae is a virulence factor that confers resistance to heat shock and oxidative stress
    Gene841, 146771-146771. PubMed  Europe PubMed DOI
    7. 2021
  7. Cao,Q., Wei,W., Wang,H., Wang,Z., Lv,Y., Dai,M., Tan,C., Chen,H. and Wang,X.
    Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration
    Virulence12, 2296-2313. PubMed  Europe PubMed DOI
  8. Harkness,R.W., Toyama,Y., Ripstein,Z.A., Zhao,H., Sever,A.I.M., Luan,Q., Brady,J.P., Clark,P.L., Schuck,P. and Kay,L.E.
    Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP
    Proc Natl Acad Sci U S A118, PubMed  Europe PubMed DOI
    9. 2020
  9. Zarzecka,U., Grinzato,A., Kandiah,E., Cysewski,D., Berto,P., Skorko-Glonek,J., Zanotti,G. and Backert,S.
    Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA
    Gut Microbes12, 1-16. PubMed  Europe PubMed DOI
    10. 2019
  10. Zhang,S., Cheng,Y., Ma,J., Wang,Y., Chang,Z. and Fu,X.
    DegP degrades a wide range of substrate proteins in Escherichia coli under stress conditions
    Biochem J476, 3549-3564. PubMed  Europe PubMed DOI
    11. 2018
  11. Fang,K., Jin,X. and Hong,S.H.
    Probiotic Escherichia coli inhibits biofilm formation of pathogenic E. coli via extracellular activity of DegP
    Sci Rep8, 4939-4939. PubMed  Europe PubMed DOI
  12. Fu,X., Wang,Y., Shao,H., Ma,J., Song,X., Zhang,M. and Chang,Z.
    DegP functions as a critical protease for bacterial acid resistance
    FEBS J285, 3525-3538. PubMed  Europe PubMed DOI
    13. 2017
  13. He,D., Xie,X., Yang,F., Zhang,H., Su,H., Ge,Y., Song,H. and Chen,P.R.
    Quantitative and comparative profiling of protease substrates through a genetically encoded multifunctional photocrosslinker
    Angew Chem Int Ed Engl56, 14521-14525. PubMed  Europe PubMed DOI  P
  14. Kim,S., Song,I., Eom,G. and Kim,S.
    A small periplasmic protein with a hydrophobic C-terminal residue enhances DegP proteolysis as a suicide activator
    J Bacteriol200, e00519-17-e00519-17. PubMed  Europe PubMed DOI
  15. Park,H., Kim,Y.T., Choi,C. and Kim,S.
    Tripodal lipoprotein variants with C-terminal hydrophobic residues allosterically modulate activity of the DegP protease
    J Mol Biol429, 3090-3101. PubMed  Europe PubMed DOI
    16. 2016
  16. Chang,Z.
    The function of the DegP (HtrA) protein: protease versus chaperone
    IUBMB Life68, 904-907. PubMed  Europe PubMed DOI
  17. Figaj,D., Gieldon,A., Bartczak,M., Koper,T., Zarzecka,U., Lesner,A., Lipinska,B. and Skorko-Glonek,J.
    The LD loop as an important structural element required for transmission of the allosteric signal in the HtrA (DegP) protease from Escherichia coli
    FEBS J283, 3471-3487. PubMed  Europe PubMed DOI  S
    18. 2015
  18. de Regt,A.K., Kim,S., Sohn,J., Grant,R.A., Baker,T.A. and Sauer,R.T.
    A conserved activation cluster is required for allosteric communication in HtrA-family proteases
    Structure23, 517-526. PubMed  Europe PubMed DOI
  19. Koper,T., Polit,A., Sobiecka-Szkatula,A., Wegrzyn,K., Scire,A., Figaj,D., Kadzinski,L., Zarzecka,U., Zurawa-Janicka,D., Banecki,B., Lesner,A., Tanfani,F., Lipinska,B. and Skorko-Glonek,J.
    Analysis of the link between the redox state and enzymatic activity of the HtrA (DegP) protein from Escherichia coli
    PLoS ONE10, e0117413-e0117413. PubMed  Europe PubMed DOI
  20. Rai,N. and Ramaswamy,A.
    Temperature dependent dynamics of DegP-trimer: a molecular dynamics study
    Comput Struct Biotechnol J13, 329-338. PubMed  Europe PubMed DOI
    21. 2014
  21. Figaj,D., Gieldon,A., Polit,A., Sobiecka-Szkatula,A., Koper,T., Denkiewicz,M., Banecki,B., Lesner,A., Ciarkowski,J., Lipinska,B. and Skorko-Glonek,J.
    The LA loop as an important regulatory element of the HtrA (DegP) protease from Escherichia coli: structural and functional studies
    J Biol Chem289, 15880-15893. PubMed  Europe PubMed DOI  S
  22. Ge,X., Wang,R., Ma,J., Liu,Y., Ezemaduka,A.N., Chen,P.R., Fu,X. and Chang,Z.
    DegP primarily functions as a protease for the biogenesis of beta-barrel outer membrane proteins in the Gram-negative bacterium Escherichia coli
    FEBS J281, 1226-1240. PubMed  Europe PubMed DOI
  23. Kim,S. and Sauer,R.T.
    Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress
    Genes Dev28, 902-911. PubMed  Europe PubMed DOI
  24. Li,S., Wang,R., Li,D., Ma,J., Li,H., He,X., Chang,Z. and Weng,Y.
    Thermal-triggerd proteinquake leads to disassembly of DegP hexamer as an imperative activation step
    Sci Rep4, 4834-4834. PubMed  Europe PubMed DOI
  25. Thompson,N.J., Merdanovic,M., Ehrmann,M., van Duijn,E. and Heck,A.J.
    Substrate occupancy at the onset of oligomeric transitions of DegP
    Structure22, 281-290. PubMed  Europe PubMed DOI
    26. 2012
  26. Kim,S. and Sauer,R.T.
    Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival
    Proc Natl Acad Sci U S A109, 7263-7268. PubMed  Europe PubMed DOI
  27. Weber,N. and Kolmar,H.
    DegP protease
    [ISSN:978-0-12-407742-3]3, 2567-2571. DOI
    28. 2011
  28. Iwanczyk,J., Leong,V. and Ortega,J.
    Factors defining the functional oligomeric state of Escherichia coli DegP protease
    PLoS ONE6, e18944-e18944. PubMed  Europe PubMed DOI
  29. Kim,S., Grant,R.A. and Sauer,R.T.
    Covalent linkage of distinct substrate degrons controls assembly and disassembly of DegP proteolytic cages
    Cell145, 67-78. PubMed  Europe PubMed DOI
  30. Singh,N., Kuppili,R.R. and Bose,K.
    The structural basis of mode of activation and functional diversity: a case study with HtrA family of serine proteases
    Arch Biochem Biophys516, 85-96. PubMed  Europe PubMed DOI  V  S
    31. 2010
  31. Jiao,X.D., Zhang,M., Cheng,S. and Sun,L.
    Analysis of Edwardsiella tarda DegP, a serine protease and a protective immunogen
    Fish Shellfish Immunol28, 672-677. PubMed  Europe PubMed DOI
  32. Krojer,T., Sawa,J., Huber,R. and Clausen,T.
    HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues
    Nat Struct Mol Biol17, 844-852. PubMed  Europe PubMed DOI
  33. Merdanovic,M., Mamant,N., Meltzer,M., Poepsel,S., Auckenthaler,A., Melgaard,R., Hauske,P., Nagel-Steger,L., Clarke,A.R., Kaiser,M., Huber,R. and Ehrmann,M.
    Determinants of structural and functional plasticity of a widely conserved protease chaperone complex
    Nat Struct Mol Biol17, 837-843. PubMed  Europe PubMed DOI
  34. Sawa,J., Heuck,A., Ehrmann,M. and Clausen,T.
    Molecular transformers in the cell: lessons learned from the DegP protease-chaperone
    Curr Opin Struct Biol20, 253-258. PubMed  Europe PubMed DOI  V
  35. Sobiecka-Szkatula,A., Gieldon,A., Scire,A., Tanfani,F., Figaj,D., Koper,T., Ciarkowski,J., Lipinska,B. and Skorko-Glonek,J.
    The role of the L2 loop in the regulation and maintaining the proteolytic activity of HtrA (DegP) protein from Escherichia coli
    Arch Biochem Biophys500, 123-130. PubMed  Europe PubMed DOI
    36. 2009
  36. Hauske,P., Meltzer,M., Ottmann,C., Krojer,T., Clausen,T., Ehrmann,M. and Kaiser,M.
    Selectivity profiling of DegP substrates and inhibitors
    Bioorg Med Chem17, 2920-2924. PubMed  Europe PubMed DOI  A  I
  37. Ingmer,H. and Brondsted,L.
    Proteases in bacterial pathogenesis
    Res Microbiol160, 704-710. PubMed  Europe PubMed DOI  V
  38. Jomaa,A., Iwanczyk,J., Tran,J. and Ortega,J.
    Characterization of the autocleavage process of the Escherichia coli HtrA protein: implications for its physiological role
    J Bacteriol191, 1924-1932. PubMed  Europe PubMed DOI
  39. Lewis,C., Skovierova,H., Rowley,G., Rezuchova,B., Homerova,D., Stevenson,A., Spencer,J., Farn,J., Kormanec,J. and Roberts,M.
    Salmonella enterica serovar typhimurium HtrA: regulation of expression and role of the chaperone and protease activities during infection
    Microbiology (Reading)155, 873-881. PubMed  Europe PubMed DOI
  40. Meltzer,M., Hasenbein,S., Mamant,N., Merdanovic,M., Poepsel,S., Hauske,P., Kaiser,M., Huber,R., Krojer,T., Clausen,T. and Ehrmann,M.
    Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli
    Res Microbiol160, 660-666. PubMed  Europe PubMed DOI  V
  41. Shen,Q.T., Bai,X.C., Chang,L.F., Wu,Y., Wang,H.W. and Sui,S.F.
    Bowl-shaped oligomeric structures on membranes as DegP's new functional forms in protein quality control
    Proc Natl Acad Sci U S A106, 4858-4863. PubMed  Europe PubMed DOI
  42. Sobiecka-Szkatula,A., Polit,A., Scire,A., Gieldon,A., Tanfani,F., Szkarlat,Z., Ciarkowski,J., Zurawa-Janicka,D., Skorko-Glonek,J. and Lipinska,B.
    Temperature-induced conformational changes within the regulatory loops L1-L2-LA of the HtrA heat-shock protease from Escherichia coli
    Biochim Biophys Acta1794, 1573-1582. PubMed  Europe PubMed DOI
  43. Subrini,O. and Betton,J.M.
    Assemblies of DegP underlie its dual chaperone and protease function
    FEMS Microbiol Lett296, 143-148. PubMed  Europe PubMed DOI
    44. 2008
  44. Huber,D. and Bukau,B.
    DegP: a Protein "Death Star"
    Structure16, 989-990. PubMed  Europe PubMed DOI
  45. Jiang,J., Zhang,X., Chen,Y., Wu,Y., Zhou,Z.H., Chang,Z. and Sui,S.F.
    Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins
    Proc Natl Acad Sci U S A105, 11939-11944. PubMed  Europe PubMed DOI
  46. Krojer,T., Pangerl,K., Kurt,J., Sawa,J., Stingl,C., Mechtler,K., Huber,R., Ehrmann,M. and Clausen,T.
    Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins
    Proc Natl Acad Sci U S A105, 7702-7707. PubMed  Europe PubMed DOI
  47. Krojer,T., Sawa,J., Schafer,E., Saibil,H.R., Ehrmann,M. and Clausen,T.
    Structural basis for the regulated protease and chaperone function of DegP
    Nature453, 885-890. PubMed  Europe PubMed DOI  S
  48. Meltzer,M., Hasenbein,S., Hauske,P., Kucz,N., Merdanovic,M., Grau,S., Beil,A., Jones,D., Krojer,T., Clausen,T., Ehrmann,M. and Kaiser,M.
    Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control
    Angew Chem Int Ed Engl47, 1332-1334. PubMed  Europe PubMed DOI
  49. Skorko-Glonek,J., Sobiecka-Szkatula,A., Narkiewicz,J. and Lipinska,B.
    The proteolytic activity of the HtrA (DegP) protein from Escherichia coli at low temperatures
    Microbiology (Reading)154, 3649-3658. PubMed  Europe PubMed DOI
    50. 2007
  50. [YEAR:2-2-2007]Iwanczyk,J., Damjanovic,D., Kooistra,J., Leong,V., Jomaa,A., Ghirlando,R. and Ortega,J.
    Role of the PDZ domains in Escherichia coli DegP protein
    J Bacteriol189, 3176-3186. PubMed  Europe PubMed DOI
  51. Jomaa,A., Damjanovic,D., Leong,V., Ghirlando,R., Iwanczyk,J. and Ortega,J.
    The inner cavity of Escherichia coli DegP protein is not essential for molecular chaperone and proteolytic activity
    J Bacteriol189, 706-716. PubMed  Europe PubMed DOI
  52. Skorko-Glonek,J., Laskowska,E., Sobiecka-Szkatula,A. and Lipinska,B.
    Characterization of the chaperone-like activity of HtrA (DegP) protein from Escherichia coli under the conditions of heat shock
    Arch Biochem Biophys464, 80-89. PubMed  Europe PubMed DOI
    53. 2006
  53. Esposito,V., Campioni,M., De Luca,A., Spugnini,E.P., Baldi,F., Cassandro,R., Mancini,A., Vincenzi,B., Groeger,A., Caputi,M. and Baldi,A.
    Analysis of HtrA1 serine protease expression in human lung cancer
    Anticancer Res26, 3455-3459. PubMed  Europe PubMed
  54. [YEAR:29-8-2006]Mo,E., Peters,S.E., Willers,C., Maskell,D.J. and Charles,I.G.
    Single, double and triple mutants of Salmonella enterica serovar Typhimurium degP (htrA), degQ (hhoA) and degS (hhoB) have diverse phenotypes on exposure to elevated temperature and their growth in vivo is attenuated to different extents
    Microb Pathog41, 174-182. PubMed  Europe PubMed DOI
  55. Redford,P. and Welch,R.A.
    Role of sigma E-regulated genes in Escherichia coli uropathogenesis
    Infect Immun74, 4030-4038. PubMed  Europe PubMed DOI
    56. 2005
  56. [YEAR:1-10-2005]Forns,N., Juarez,A. and Madrid,C.
    Osmoregulation of the HtrA (DegP) protease of Escherichia coli: an Hha-H-NS complex represses HtrA expression at low osmolarity
    FEMS Microbiol Lett251, 75-80. PubMed  Europe PubMed DOI
  57. [YEAR:22-11-2005]Isaac,D.D., Pinkner,J.S., Hultgren,S.J. and Silhavy,T.J.
    The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP
    Proc Natl Acad Sci U S A102, 17775-17779. PubMed  Europe PubMed DOI
  58. Rosch,J.W. and Caparon,M.G.
    The ExPortal: an organelle dedicated to the biogenesis of secreted proteins in Streptococcus pyogenes
    Mol Microbiol58, 959-968. PubMed  Europe PubMed DOI
  59. Sebert,M.E., Patel,K.P., Plotnick,M. and Weiser,J.N.
    Pneumococcal HtrA protease mediates inhibition of competence by the CiaRH two-component signaling system
    J Bacteriol187, 3969-3979. PubMed  Europe PubMed DOI
    60. 2004
  60. [YEAR:16-2-2004]Heusipp,G., Nelson,K.M., Schmidt,M.A. and Miller,V.L.
    Regulation of htrA expression in Yersinia enterocolitica
    FEMS Microbiol Lett231, 227-235. PubMed  Europe PubMed DOI
  61. Kolmar,H.
    DegP or protease Do
    [ISSN:0-12-079610-4]2, 1472-1476.  V
  62. Lyon,W.R. and Caparon,M.G.
    Role for serine protease HtrA (DegP) of Streptococcus pyogenes in the biogenesis of virulence factors SpeB and the hemolysin streptolysin S
    Infect Immun72, 1618-1625. PubMed  Europe PubMed DOI
    63. 2003
  63. [YEAR:15-7-2003]Foucaud-Scheunemann,C. and Poquet,I.
    HtrA is a key factor in the response to specific stress conditions in Lactococcus lactis
    FEMS Microbiol Lett224, 53-59. PubMed  Europe PubMed DOI
  64. [YEAR:30-7-2003]Skorko-Glonek,J., Zurawa,D., Tanfani,F., Scire,A., Wawrzynow,A., Narkiewicz,J., Bertoli,E. and Lipinska,B.
    The N-terminal region of HtrA heat shock protease from Escherichia coli is essential for stabilization of HtrA primary structure and maintaining of its oligomeric structure
    Biochim Biophys Acta1649, 171-182. PubMed  Europe PubMed DOI
    65. 2002
  65. Jones,C.H., Dexter,P., Evans,A.K., Liu,C., Hultgren,S.J. and Hruby,D.E.
    Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin
    J Bacteriol184, 5762-5771. PubMed  Europe PubMed DOI
  66. [YEAR:28-3-2002]Krojer,T., Garrido-Franco,M., Huber,R., Ehrmann,M. and Clausen,T.
    Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine
    Nature416, 455-459. PubMed  Europe PubMed DOI  S
  67. [YEAR:18-10-2002]Spiers,A., Lamb,H.K., Cocklin,S., Wheeler,K.A., Budworth,J., Dodds,A.L., Pallen,M.J., Maskell,D.J., Charles,I.G. and Hawkins,A.R.
    PDZ domains facilitate binding of high temperature requirement protease A (HtrA) and tail-specific protease (Tsp) to heterologous substrates through recognition of the small stable RNA A (ssrA)-encoded peptide
    J Biol Chem277, 39443-39449. PubMed  Europe PubMed DOI
    68. 2001
  68. [YEAR:20-6-2001]Lin,W.J., Huang,S.W. and Chou,C.P.
    DegP-coexpression minimizes inclusion-body formation upon overproduction of recombinant penicillin acylase in Escherichia coli
    Biotechnol Bioeng73, 484-492. PubMed  Europe PubMed DOI
    69. 2000
  69. Misra,R., CastilloKeller,M. and Deng,M.
    Overexpression of protease-deficient DegP(S210A) rescues the lethal phenotype of Escherichia coli OmpF assembly mutants in a degP background
    J Bacteriol182, 4882-4888. PubMed  Europe PubMed DOI
  70. [YEAR:15-5-2000]Williams,K., Oyston,P.C., Dorrell,N., Li,S., Titball,R.W. and Wren,B.W.
    Investigation into the role of the serine protease HtrA in Yersinia pestis pathogenesis
    FEMS Microbiol Lett186, 281-286. PubMed  Europe PubMed DOI
    71. 1999
  71. [YEAR:17-12-1999]Kim,K.I., Park,S.C., Kang,S.H., Cheong,G.W. and Chung,C.H.
    Selective degradation of unfolded proteins by the self-compartmentalizing HtrA protease, a periplasmic heat shock protein in Escherichia coli
    J Mol Biol294, 1363-1374. PubMed  Europe PubMed DOI  S
  72. Sassoon,N., Arie,J.P. and Betton,J.M.
    PDZ domains determine the native oligomeric structure of the DegP (HtrA) protease
    Mol Microbiol33, 583-589. PubMed  Europe PubMed DOI
  73. Skorko-Glonek,J., Zurawa,D., Kuczwara,E., Wozniak,M., Wypych,Z. and Lipinska,B.
    The Escherichia coli heat shock protease HtrA participates in defense against oxidative stress
    Mol Gen Genet262, 342-350. PubMed  Europe PubMed DOI
  74. [YEAR:30-4-1999]Spiess,C., Beil,A. and Ehrmann,M.
    A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein
    Cell97, 339-347. PubMed  Europe PubMed DOI
    75. 1997
  75. Pallen,M.J. and Wren,B.W.
    The HtrA family of serine proteases
    Mol Microbiol26, 209-221. PubMed  Europe PubMed
  76. [YEAR:4-4-1997]Skorko-Glonek,J., Lipinska,B., Krzewski,K., Zolese,G., Bertoli,E. and Tanfani,F.
    HtrA heat shock protease interacts with phospholipid membranes and undergoes conformational changes
    J Biol Chem272, 8974-8982. PubMed  Europe PubMed
    77. 1996
  77. Kolmar,H., Waller,P.R. and Sauer,R.T.
    The DegP and DegQ periplasmic endoproteases of Escherichia coli: Specificity for cleavage sites and substrate conformation
    J Bacteriol178, 5925-5929. PubMed  Europe PubMed
    78. 1995
  78. Cavard,D.
    Role of DegP protease on levels of various forms of colicin A lysis protein
    FEMS Microbiol Lett125, 173-178. PubMed  Europe PubMed DOI
  79. Skorko-Glonek,J., Wawrzynow,A., Krzewski,K., Kurpierz,K. and Lipinska,B.
    Site-directed mutagenesis of the HtrA(DegP) serine protease, whose proteolytic activity is indispensable for Escherichia coli survival at elevated temperatures
    Gene163, 47-52. PubMed  Europe PubMed DOI
    80. 1993
  80. Yoo,S.J., Seol,J.H., Woo,S.K., Suh,S.W., Hwang,D.S., Ha,D.B. and Chung,C.H.
    Hydrolysis of the IciA protein, an inhibitor of DNA replication initiation, by protease Do in Escherichia coli
    FEBS Lett327, 17-20. PubMed  Europe PubMed DOI
    81. 1991
  81. Baird,L., Lipinska,B., Raina,S. and Georgopoulos,C.
    Identification of the Escherichia coli sohB gene, a multicopy suppressor of the Htra (DegP) null phenotype
    J Bacteriol173, 5763-5770. PubMed  Europe PubMed
  82. Johnson,K.I., Charles,I., Dougan,G., Pickard,D., O'Gaora,P., Costa,G., Ali,T., Miller,I. and Hormaeche,C.
    The role of a stress-response protein in Salmonella typhimurium virulence
    Mol Microbiol5, 401-407. PubMed  Europe PubMed
  83. Seol,J.H., Woo,S.K., Jung,E.M., Yoo,S.J., Lee,C.S., Kim,K.J., Tanaka,K., Ichihara,A., Ha,D.B. and Chung,C.H.
    Protease Do is essential for survival of Escherichia coli at high temperatures: Its identity with the htrA gene product
    Biochem Biophys Res Commun176, 730-736. PubMed  Europe PubMed
    84. 1990
  84. Lee,C.S., Hahm,J.K., Hwang,B.J., Park,K.C., Ha,D.B., Park,S.D. and Chung,C.H.
    Processing of Ada protein by two serine endoproteases Do and So from Escherichia coli
    FEBS Lett262, 310-312. PubMed  Europe PubMed DOI
  85. Lipinska,B., Zylicz,M. and Georgopoulos,C.
    The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase
    J Bacteriol172, 1791-1797. PubMed  Europe PubMed
    86. 1989
  86. Lipinska,B., Fayet,O., Baird,L. and Georgopoulos,C.
    Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures
    J Bacteriol171, 1574-1584. PubMed  Europe PubMed
  87. Strauch,K.L., Johnson,K. and Beckwith,J.
    Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature
    J Bacteriol171, 2689-2696. PubMed  Europe PubMed
    88. 1988
  88. Lipinska,B., Sharma,S. and Georgopoulos,C.
    Sequence analysis and regulation of the htrA gene of Escherichia coli: a sigma32-independent mechanism of heat-inducible transcription
    Nucleic Acids Res16, 10053-10067. PubMed  Europe PubMed
  89. Strauch,K.L. and Beckwith,J.
    An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins
    Proc Natl Acad Sci U S A85, 1576-1580. PubMed  Europe PubMed
    90. 1983
  90. Swamy,K.H., Chung,C.H. and Goldberg,A.L.
    Isolation and characterization of protease Do from Escherichia coli, a large serine protease containing multiple subunits
    Arch Biochem Biophys224, 543-554. PubMed  Europe PubMed

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