Literature for peptidase S01.273: DegP peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, I Inhibitor, P Specificity, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025

Gonzalez,L.J., Hita,F.J., Pontoriero,L., Pierattelli,R., Binolfi,A. and Vila,A.J. Periplasmic protein quality control at atomic level in live cells Nat Commun (2025) 16, 8366-8366. PubMed Europe PubMed DOI PMC EPMC
Ludwig,K. and Heidorn-Czarna,M. Mitochondrial Proteases and Their Roles in Mitophagy in Plants, Animals, and Yeast Plant Cell Physiol (2025) PubMed Europe PubMed DOI V

2024

Chen,M., Shang,Y., Cui,W., Wang,X., Zhu,J., Dong,H., Wang,H., Su,T., Wang,W., Zhang,K., Li,B., Xu,S., Hu,W., Zhang,F. and Gu,L. Molecular mechanism of proteolytic cleavage-dependent activation of CadC-mediated response to acid in E. coli Commun Biol (2024) 7, 1335-1335. PubMed Europe PubMed DOI PMC EPMC
Harkness,R.W., Zhao,H., Toyama,Y., Schuck,P. and Kay,L.E. Exploring Host-Guest Interactions within a 600 kDa DegP Protease Cage Complex Using Hydrodynamics Measurements and Methyl-TROSY NMR J Am Chem Soc (2024) 146, 8242-8259. PubMed Europe PubMed DOI

2023

Jeong,B., Jang,H.A., Lee,J., Bae,H.R. and Kim,J.K. Proteolytic Activity of DegP Is Required for the Burkholderia Symbiont To Persist in Its Host Bean Bug Microbiol Spectr (2023) 11, e0433022-e0433022. PubMed Europe PubMed DOI PMC EPMC
Zhang,X., Lin,Y., Xu,X., Wen,S., Wang,Z., Gu,J., He,Q. and Cai,X. HtrA is involved in stress response and adhesion in Glaesserella parasuis serovar 5 strain Nagasaki Vet Microbiol (2023) 282, 109748-109748. PubMed Europe PubMed DOI

2022

Zhang,L., Zhao,F., Xu,H., Chen,Y., Qi,C. and Liu,J. HtrA of Actinobacillus pleuropneumoniae is a virulence factor that confers resistance to heat shock and oxidative stress Gene (2022) 841, 146771-146771. PubMed Europe PubMed DOI

2021

Cao,Q., Wei,W., Wang,H., Wang,Z., Lv,Y., Dai,M., Tan,C., Chen,H. and Wang,X. Cleavage of E-cadherin by porcine respiratory bacterial pathogens facilitates airway epithelial barrier disruption and bacterial paracellular transmigration Virulence (2021) 12, 2296-2313. PubMed Europe PubMed DOI PMC EPMC
Harkness,R.W., Toyama,Y., Ripstein,Z.A., Zhao,H., Sever,A.I.M., Luan,Q., Brady,J.P., Clark,P.L., Schuck,P. and Kay,L.E. Competing stress-dependent oligomerization pathways regulate self-assembly of the periplasmic protease-chaperone DegP Proc Natl Acad Sci U S A (2021) 118 PubMed Europe PubMed DOI PMC EPMC

2020

Zarzecka,U., Grinzato,A., Kandiah,E., Cysewski,D., Berto,P., Skorko-Glonek,J., Zanotti,G. and Backert,S. Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA Gut Microbes (2020) 12, 1-16. PubMed Europe PubMed DOI PMC EPMC

2019

Zhang,S., Cheng,Y., Ma,J., Wang,Y., Chang,Z. and Fu,X. DegP degrades a wide range of substrate proteins in Escherichia coli under stress conditions Biochem J (2019) 476, 3549-3564. PubMed Europe PubMed DOI

2018

Fang,K., Jin,X. and Hong,S.H. Probiotic Escherichia coli inhibits biofilm formation of pathogenic E. coli via extracellular activity of DegP Sci Rep (2018) 8, 4939-4939. PubMed Europe PubMed DOI PMC EPMC
Fu,X., Wang,Y., Shao,H., Ma,J., Song,X., Zhang,M. and Chang,Z. DegP functions as a critical protease for bacterial acid resistance FEBS J (2018) 285, 3525-3538. PubMed Europe PubMed DOI

2017

He,D., Xie,X., Yang,F., Zhang,H., Su,H., Ge,Y., Song,H. and Chen,P.R. Quantitative and comparative profiling of protease substrates through a genetically encoded multifunctional photocrosslinker Angew Chem Int Ed Engl (2017) 56, 14521-14525. PubMed Europe PubMed DOI P
Kim,S., Song,I., Eom,G. and Kim,S. A small periplasmic protein with a hydrophobic C-terminal residue enhances DegP proteolysis as a suicide activator J Bacteriol (2017) 200, e00519-17-e00519-17. PubMed Europe PubMed DOI
Park,H., Kim,Y.T., Choi,C. and Kim,S. Tripodal lipoprotein variants with C-terminal hydrophobic residues allosterically modulate activity of the DegP protease J Mol Biol (2017) 429, 3090-3101. PubMed Europe PubMed DOI

2016

Chang,Z. The function of the DegP (HtrA) protein: protease versus chaperone IUBMB Life (2016) 68, 904-907. PubMed Europe PubMed DOI
Figaj,D., Gieldon,A., Bartczak,M., Koper,T., Zarzecka,U., Lesner,A., Lipinska,B. and Skorko-Glonek,J. The LD loop as an important structural element required for transmission of the allosteric signal in the HtrA (DegP) protease from Escherichia coli FEBS J (2016) 283, 3471-3487. PubMed Europe PubMed DOI S

2015

de Regt,A.K., Kim,S., Sohn,J., Grant,R.A., Baker,T.A. and Sauer,R.T. A conserved activation cluster is required for allosteric communication in HtrA-family proteases Structure (2015) 23, 517-526. PubMed Europe PubMed DOI
Koper,T., Polit,A., Sobiecka-Szkatula,A., Wegrzyn,K., Scire,A., Figaj,D., Kadzinski,L., Zarzecka,U., Zurawa-Janicka,D., Banecki,B., Lesner,A., Tanfani,F., Lipinska,B. and Skorko-Glonek,J. Analysis of the link between the redox state and enzymatic activity of the HtrA (DegP) protein from Escherichia coli PLoS ONE (2015) 10, e0117413-e0117413. PubMed Europe PubMed DOI PMC EPMC
Rai,N. and Ramaswamy,A. Temperature dependent dynamics of DegP-trimer: a molecular dynamics study Comput Struct Biotechnol J (2015) 13, 329-338. PubMed Europe PubMed DOI PMC EPMC

2014

Figaj,D., Gieldon,A., Polit,A., Sobiecka-Szkatula,A., Koper,T., Denkiewicz,M., Banecki,B., Lesner,A., Ciarkowski,J., Lipinska,B. and Skorko-Glonek,J. The LA loop as an important regulatory element of the HtrA (DegP) protease from Escherichia coli: structural and functional studies J Biol Chem (2014) 289, 15880-15893. PubMed Europe PubMed DOI S
Ge,X., Wang,R., Ma,J., Liu,Y., Ezemaduka,A.N., Chen,P.R., Fu,X. and Chang,Z. DegP primarily functions as a protease for the biogenesis of beta-barrel outer membrane proteins in the Gram-negative bacterium Escherichia coli FEBS J (2014) 281, 1226-1240. PubMed Europe PubMed DOI
Kim,S. and Sauer,R.T. Distinct regulatory mechanisms balance DegP proteolysis to maintain cellular fitness during heat stress Genes Dev (2014) 28, 902-911. PubMed Europe PubMed DOI
Li,S., Wang,R., Li,D., Ma,J., Li,H., He,X., Chang,Z. and Weng,Y. Thermal-triggerd proteinquake leads to disassembly of DegP hexamer as an imperative activation step Sci Rep (2014) 4, 4834-4834. PubMed Europe PubMed DOI PMC EPMC
Thompson,N.J., Merdanovic,M., Ehrmann,M., van Duijn,E. and Heck,A.J. Substrate occupancy at the onset of oligomeric transitions of DegP Structure (2014) 22, 281-290. PubMed Europe PubMed DOI

2012

Kim,S. and Sauer,R.T. Cage assembly of DegP protease is not required for substrate-dependent regulation of proteolytic activity or high-temperature cell survival Proc Natl Acad Sci U S A (2012) 109, 7263-7268. PubMed Europe PubMed DOI
Weber,N. and Kolmar,H. DegP protease [ISSN:978-0-12-407742-3] (2012) 3, 2567-2571. DOI

2011

Iwanczyk,J., Leong,V. and Ortega,J. Factors defining the functional oligomeric state of Escherichia coli DegP protease PLoS ONE (2011) 6, e18944-e18944. PubMed Europe PubMed DOI PMC EPMC
Kim,S., Grant,R.A. and Sauer,R.T. Covalent linkage of distinct substrate degrons controls assembly and disassembly of DegP proteolytic cages Cell (2011) 145, 67-78. PubMed Europe PubMed DOI PMC EPMC
Singh,N., Kuppili,R.R. and Bose,K. The structural basis of mode of activation and functional diversity: a case study with HtrA family of serine proteases Arch Biochem Biophys (2011) 516, 85-96. PubMed Europe PubMed DOI V S

2010

Jiao,X.D., Zhang,M., Cheng,S. and Sun,L. Analysis of Edwardsiella tarda DegP, a serine protease and a protective immunogen Fish Shellfish Immunol (2010) 28, 672-677. PubMed Europe PubMed DOI
Krojer,T., Sawa,J., Huber,R. and Clausen,T. HtrA proteases have a conserved activation mechanism that can be triggered by distinct molecular cues Nat Struct Mol Biol (2010) 17, 844-852. PubMed Europe PubMed DOI
Merdanovic,M., Mamant,N., Meltzer,M., Poepsel,S., Auckenthaler,A., Melgaard,R., Hauske,P., Nagel-Steger,L., Clarke,A.R., Kaiser,M., Huber,R. and Ehrmann,M. Determinants of structural and functional plasticity of a widely conserved protease chaperone complex Nat Struct Mol Biol (2010) 17, 837-843. PubMed Europe PubMed DOI
Sawa,J., Heuck,A., Ehrmann,M. and Clausen,T. Molecular transformers in the cell: lessons learned from the DegP protease-chaperone Curr Opin Struct Biol (2010) 20, 253-258. PubMed Europe PubMed DOI V
Sobiecka-Szkatula,A., Gieldon,A., Scire,A., Tanfani,F., Figaj,D., Koper,T., Ciarkowski,J., Lipinska,B. and Skorko-Glonek,J. The role of the L2 loop in the regulation and maintaining the proteolytic activity of HtrA (DegP) protein from Escherichia coli Arch Biochem Biophys (2010) 500, 123-130. PubMed Europe PubMed DOI

2009

Hauske,P., Meltzer,M., Ottmann,C., Krojer,T., Clausen,T., Ehrmann,M. and Kaiser,M. Selectivity profiling of DegP substrates and inhibitors Bioorg Med Chem (2009) 17, 2920-2924. PubMed Europe PubMed DOI A I
Ingmer,H. and Brondsted,L. Proteases in bacterial pathogenesis Res Microbiol (2009) 160, 704-710. PubMed Europe PubMed DOI V
Jomaa,A., Iwanczyk,J., Tran,J. and Ortega,J. Characterization of the autocleavage process of the Escherichia coli HtrA protein: implications for its physiological role J Bacteriol (2009) 191, 1924-1932. PubMed Europe PubMed DOI PMC EPMC
Lewis,C., Skovierova,H., Rowley,G., Rezuchova,B., Homerova,D., Stevenson,A., Spencer,J., Farn,J., Kormanec,J. and Roberts,M. Salmonella enterica serovar typhimurium HtrA: regulation of expression and role of the chaperone and protease activities during infection Microbiology (Reading) (2009) 155, 873-881. PubMed Europe PubMed DOI
Meltzer,M., Hasenbein,S., Mamant,N., Merdanovic,M., Poepsel,S., Hauske,P., Kaiser,M., Huber,R., Krojer,T., Clausen,T. and Ehrmann,M. Structure, function and regulation of the conserved serine proteases DegP and DegS of Escherichia coli Res Microbiol (2009) 160, 660-666. PubMed Europe PubMed DOI V
Shen,Q.T., Bai,X.C., Chang,L.F., Wu,Y., Wang,H.W. and Sui,S.F. Bowl-shaped oligomeric structures on membranes as DegP's new functional forms in protein quality control Proc Natl Acad Sci U S A (2009) 106, 4858-4863. PubMed Europe PubMed DOI PMC EPMC
Sobiecka-Szkatula,A., Polit,A., Scire,A., Gieldon,A., Tanfani,F., Szkarlat,Z., Ciarkowski,J., Zurawa-Janicka,D., Skorko-Glonek,J. and Lipinska,B. Temperature-induced conformational changes within the regulatory loops L1-L2-LA of the HtrA heat-shock protease from Escherichia coli Biochim Biophys Acta (2009) 1794, 1573-1582. PubMed Europe PubMed DOI
Subrini,O. and Betton,J.M. Assemblies of DegP underlie its dual chaperone and protease function FEMS Microbiol Lett (2009) 296, 143-148. PubMed Europe PubMed DOI

2008

Huber,D. and Bukau,B. DegP: a Protein "Death Star" Structure (2008) 16, 989-990. PubMed Europe PubMed DOI
Jiang,J., Zhang,X., Chen,Y., Wu,Y., Zhou,Z.H., Chang,Z. and Sui,S.F. Activation of DegP chaperone-protease via formation of large cage-like oligomers upon binding to substrate proteins Proc Natl Acad Sci U S A (2008) 105, 11939-11944. PubMed Europe PubMed DOI PMC EPMC
Krojer,T., Sawa,J., Schafer,E., Saibil,H.R., Ehrmann,M. and Clausen,T. Structural basis for the regulated protease and chaperone function of DegP Nature (2008) 453, 885-890. PubMed Europe PubMed DOI S
Krojer,T., Pangerl,K., Kurt,J., Sawa,J., Stingl,C., Mechtler,K., Huber,R., Ehrmann,M. and Clausen,T. Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins Proc Natl Acad Sci U S A (2008) 105, 7702-7707. PubMed Europe PubMed DOI PMC EPMC
Meltzer,M., Hasenbein,S., Hauske,P., Kucz,N., Merdanovic,M., Grau,S., Beil,A., Jones,D., Krojer,T., Clausen,T., Ehrmann,M. and Kaiser,M. Allosteric activation of HtrA protease DegP by stress signals during bacterial protein quality control Angew Chem Int Ed Engl (2008) 47, 1332-1334. PubMed Europe PubMed DOI
Skorko-Glonek,J., Sobiecka-Szkatula,A., Narkiewicz,J. and Lipinska,B. The proteolytic activity of the HtrA (DegP) protein from Escherichia coli at low temperatures Microbiology (Reading) (2008) 154, 3649-3658. PubMed Europe PubMed DOI

2007

[YEAR:2-2-2007]Iwanczyk,J., Damjanovic,D., Kooistra,J., Leong,V., Jomaa,A., Ghirlando,R. and Ortega,J. Role of the PDZ domains in Escherichia coli DegP protein J Bacteriol (2-2-2007) 189, 3176-3186. PubMed Europe PubMed DOI PMC EPMC
Jomaa,A., Damjanovic,D., Leong,V., Ghirlando,R., Iwanczyk,J. and Ortega,J. The inner cavity of Escherichia coli DegP protein is not essential for molecular chaperone and proteolytic activity J Bacteriol (2007) 189, 706-716. PubMed Europe PubMed DOI PMC EPMC
Skorko-Glonek,J., Laskowska,E., Sobiecka-Szkatula,A. and Lipinska,B. Characterization of the chaperone-like activity of HtrA (DegP) protein from Escherichia coli under the conditions of heat shock Arch Biochem Biophys (2007) 464, 80-89. PubMed Europe PubMed DOI

2006

Esposito,V., Campioni,M., De Luca,A., Spugnini,E.P., Baldi,F., Cassandro,R., Mancini,A., Vincenzi,B., Groeger,A., Caputi,M. and Baldi,A. Analysis of HtrA1 serine protease expression in human lung cancer Anticancer Res (2006) 26, 3455-3459. PubMed Europe PubMed
[YEAR:29-8-2006]Mo,E., Peters,S.E., Willers,C., Maskell,D.J. and Charles,I.G. Single, double and triple mutants of Salmonella enterica serovar Typhimurium degP (htrA), degQ (hhoA) and degS (hhoB) have diverse phenotypes on exposure to elevated temperature and their growth in vivo is attenuated to different extents Microb Pathog (29-8-2006) 41, 174-182. PubMed Europe PubMed DOI
Redford,P. and Welch,R.A. Role of sigma E-regulated genes in Escherichia coli uropathogenesis Infect Immun (2006) 74, 4030-4038. PubMed Europe PubMed DOI PMC EPMC

2005

[YEAR:1-10-2005]Forns,N., Juarez,A. and Madrid,C. Osmoregulation of the HtrA (DegP) protease of Escherichia coli: an Hha-H-NS complex represses HtrA expression at low osmolarity FEMS Microbiol Lett (1-10-2005) 251, 75-80. PubMed Europe PubMed DOI
[YEAR:22-11-2005]Isaac,D.D., Pinkner,J.S., Hultgren,S.J. and Silhavy,T.J. The extracytoplasmic adaptor protein CpxP is degraded with substrate by DegP Proc Natl Acad Sci U S A (22-11-2005) 102, 17775-17779. PubMed Europe PubMed DOI PMC EPMC
Rosch,J.W. and Caparon,M.G. The ExPortal: an organelle dedicated to the biogenesis of secreted proteins in Streptococcus pyogenes Mol Microbiol (2005) 58, 959-968. PubMed Europe PubMed DOI
Sebert,M.E., Patel,K.P., Plotnick,M. and Weiser,J.N. Pneumococcal HtrA protease mediates inhibition of competence by the CiaRH two-component signaling system J Bacteriol (2005) 187, 3969-3979. PubMed Europe PubMed DOI PMC EPMC

2004

[YEAR:16-2-2004]Heusipp,G., Nelson,K.M., Schmidt,M.A. and Miller,V.L. Regulation of htrA expression in Yersinia enterocolitica FEMS Microbiol Lett (16-2-2004) 231, 227-235. PubMed Europe PubMed DOI
Kolmar,H. DegP or protease Do [ISSN:0-12-079610-4] (2004) 2, 1472-1476. V
Lyon,W.R. and Caparon,M.G. Role for serine protease HtrA (DegP) of Streptococcus pyogenes in the biogenesis of virulence factors SpeB and the hemolysin streptolysin S Infect Immun (2004) 72, 1618-1625. PubMed Europe PubMed DOI PMC EPMC

2003

[YEAR:15-7-2003]Foucaud-Scheunemann,C. and Poquet,I. HtrA is a key factor in the response to specific stress conditions in Lactococcus lactis FEMS Microbiol Lett (15-7-2003) 224, 53-59. PubMed Europe PubMed DOI
[YEAR:30-7-2003]Skorko-Glonek,J., Zurawa,D., Tanfani,F., Scire,A., Wawrzynow,A., Narkiewicz,J., Bertoli,E. and Lipinska,B. The N-terminal region of HtrA heat shock protease from Escherichia coli is essential for stabilization of HtrA primary structure and maintaining of its oligomeric structure Biochim Biophys Acta (30-7-2003) 1649, 171-182. PubMed Europe PubMed DOI

2002

Jones,C.H., Dexter,P., Evans,A.K., Liu,C., Hultgren,S.J. and Hruby,D.E. Escherichia coli DegP protease cleaves between paired hydrophobic residues in a natural substrate: the PapA pilin J Bacteriol (2002) 184, 5762-5771. PubMed Europe PubMed DOI PMC EPMC
[YEAR:28-3-2002]Krojer,T., Garrido-Franco,M., Huber,R., Ehrmann,M. and Clausen,T. Crystal structure of DegP (HtrA) reveals a new protease-chaperone machine Nature (28-3-2002) 416, 455-459. PubMed Europe PubMed DOI S
[YEAR:18-10-2002]Spiers,A., Lamb,H.K., Cocklin,S., Wheeler,K.A., Budworth,J., Dodds,A.L., Pallen,M.J., Maskell,D.J., Charles,I.G. and Hawkins,A.R. PDZ domains facilitate binding of high temperature requirement protease A (HtrA) and tail-specific protease (Tsp) to heterologous substrates through recognition of the small stable RNA A (ssrA)-encoded peptide J Biol Chem (18-10-2002) 277, 39443-39449. PubMed Europe PubMed DOI

2001

[YEAR:20-6-2001]Lin,W.J., Huang,S.W. and Chou,C.P. DegP-coexpression minimizes inclusion-body formation upon overproduction of recombinant penicillin acylase in Escherichia coli Biotechnol Bioeng (20-6-2001) 73, 484-492. PubMed Europe PubMed DOI

2000

Misra,R., CastilloKeller,M. and Deng,M. Overexpression of protease-deficient DegP(S210A) rescues the lethal phenotype of Escherichia coli OmpF assembly mutants in a degP background J Bacteriol (2000) 182, 4882-4888. PubMed Europe PubMed DOI PMC EPMC
[YEAR:15-5-2000]Williams,K., Oyston,P.C., Dorrell,N., Li,S., Titball,R.W. and Wren,B.W. Investigation into the role of the serine protease HtrA in Yersinia pestis pathogenesis FEMS Microbiol Lett (15-5-2000) 186, 281-286. PubMed Europe PubMed DOI

1999

[YEAR:17-12-1999]Kim,K.I., Park,S.C., Kang,S.H., Cheong,G.W. and Chung,C.H. Selective degradation of unfolded proteins by the self-compartmentalizing HtrA protease, a periplasmic heat shock protein in Escherichia coli J Mol Biol (17-12-1999) 294, 1363-1374. PubMed Europe PubMed DOI S
Sassoon,N., Arie,J.P. and Betton,J.M. PDZ domains determine the native oligomeric structure of the DegP (HtrA) protease Mol Microbiol (1999) 33, 583-589. PubMed Europe PubMed DOI
Skorko-Glonek,J., Zurawa,D., Kuczwara,E., Wozniak,M., Wypych,Z. and Lipinska,B. The Escherichia coli heat shock protease HtrA participates in defense against oxidative stress Mol Gen Genet (1999) 262, 342-350. PubMed Europe PubMed DOI
[YEAR:30-4-1999]Spiess,C., Beil,A. and Ehrmann,M. A temperature-dependent switch from chaperone to protease in a widely conserved heat shock protein Cell (30-4-1999) 97, 339-347. PubMed Europe PubMed DOI

1997

Pallen,M.J. and Wren,B.W. The HtrA family of serine proteases Mol Microbiol (1997) 26, 209-221. PubMed Europe PubMed
[YEAR:4-4-1997]Skorko-Glonek,J., Lipinska,B., Krzewski,K., Zolese,G., Bertoli,E. and Tanfani,F. HtrA heat shock protease interacts with phospholipid membranes and undergoes conformational changes J Biol Chem (4-4-1997) 272, 8974-8982. PubMed Europe PubMed

1996

Kolmar,H., Waller,P.R. and Sauer,R.T. The DegP and DegQ periplasmic endoproteases of Escherichia coli: Specificity for cleavage sites and substrate conformation J Bacteriol (1996) 178, 5925-5929. PubMed Europe PubMed PMC EPMC

1995

Cavard,D. Role of DegP protease on levels of various forms of colicin A lysis protein FEMS Microbiol Lett (1995) 125, 173-178. PubMed Europe PubMed DOI
Skorko-Glonek,J., Wawrzynow,A., Krzewski,K., Kurpierz,K. and Lipinska,B. Site-directed mutagenesis of the HtrA(DegP) serine protease, whose proteolytic activity is indispensable for Escherichia coli survival at elevated temperatures Gene (1995) 163, 47-52. PubMed Europe PubMed DOI

1993

Yoo,S.J., Seol,J.H., Woo,S.K., Suh,S.W., Hwang,D.S., Ha,D.B. and Chung,C.H. Hydrolysis of the IciA protein, an inhibitor of DNA replication initiation, by protease Do in Escherichia coli FEBS Lett (1993) 327, 17-20. PubMed Europe PubMed DOI

1991

Baird,L., Lipinska,B., Raina,S. and Georgopoulos,C. Identification of the Escherichia coli sohB gene, a multicopy suppressor of the Htra (DegP) null phenotype J Bacteriol (1991) 173, 5763-5770. PubMed Europe PubMed PMC EPMC
Johnson,K.I., Charles,I., Dougan,G., Pickard,D., O'Gaora,P., Costa,G., Ali,T., Miller,I. and Hormaeche,C. The role of a stress-response protein in Salmonella typhimurium virulence Mol Microbiol (1991) 5, 401-407. PubMed Europe PubMed
Seol,J.H., Woo,S.K., Jung,E.M., Yoo,S.J., Lee,C.S., Kim,K.J., Tanaka,K., Ichihara,A., Ha,D.B. and Chung,C.H. Protease Do is essential for survival of Escherichia coli at high temperatures: Its identity with the htrA gene product Biochem Biophys Res Commun (1991) 176, 730-736. PubMed Europe PubMed

1990

Lee,C.S., Hahm,J.K., Hwang,B.J., Park,K.C., Ha,D.B., Park,S.D. and Chung,C.H. Processing of Ada protein by two serine endoproteases Do and So from Escherichia coli FEBS Lett (1990) 262, 310-312. PubMed Europe PubMed DOI
Lipinska,B., Zylicz,M. and Georgopoulos,C. The HtrA (DegP) protein, essential for Escherichia coli survival at high temperatures, is an endopeptidase J Bacteriol (1990) 172, 1791-1797. PubMed Europe PubMed PMC EPMC

1989

Lipinska,B., Fayet,O., Baird,L. and Georgopoulos,C. Identification, characterization, and mapping of the Escherichia coli htrA gene, whose product is essential for bacterial growth only at elevated temperatures J Bacteriol (1989) 171, 1574-1584. PubMed Europe PubMed PMC EPMC
Strauch,K.L., Johnson,K. and Beckwith,J. Characterization of degP, a gene required for proteolysis in the cell envelope and essential for growth of Escherichia coli at high temperature J Bacteriol (1989) 171, 2689-2696. PubMed Europe PubMed PMC EPMC

1988

Lipinska,B., Sharma,S. and Georgopoulos,C. Sequence analysis and regulation of the htrA gene of Escherichia coli: a sigma32-independent mechanism of heat-inducible transcription Nucleic Acids Res (1988) 16, 10053-10067. PubMed Europe PubMed PMC EPMC
Strauch,K.L. and Beckwith,J. An Escherichia coli mutation preventing degradation of abnormal periplasmic proteins Proc Natl Acad Sci U S A (1988) 85, 1576-1580. PubMed Europe PubMed PMC EPMC

1983

Swamy,K.H., Chung,C.H. and Goldberg,A.L. Isolation and characterization of protease Do from Escherichia coli, a large serine protease containing multiple subunits Arch Biochem Biophys (1983) 224, 543-554. PubMed Europe PubMed