Substrates for peptidase S01.186: snake venom plasminogen activator

Summary Alignment Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
D-Phe-Pip-Arg-NHPhNO2 (S-2238)			D-Phe-Pip-Arg+NHPhNO2	S	-	DPh	Pip	Arg	NAN	-	-	-	Braud et al., 2000
D-Val-Gly-Arg-NHPhNO2			D-Val-Gly-Arg+NHPhNO2	S	-	DVa	Gly	Arg	NAN	-	-	-	Braud et al., 2000
D-Val-Leu-Arg-NHPhNO2 (S-2266)			D-Val-Leu-Arg+NHPhNO2	S	-	DVa	Leu	Arg	NAN	-	-	-	Braud et al., 2000
D-Val-Leu-Lys-NHPhNO2			D-Val-Leu-Lys+NHPhNO2	S	-	DVa	Leu	Lys	NAN	-	-	-	Jin et al., 2005
plasminogen	P00747	20-810	peptide-Arg561+Val-peptide	P	Cys	Pro	Gly	Arg	Val	Val	Gly	Gly	Zhang et al., 1997