Substrates for peptidase M50.004: RseP peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
beta-lactamase TEM	P62593	1-23	peptide-Pro12+Phe-peptide	P	MS	Ala	Leu	Ile	Pro	Phe	Phe	Ala	Ala	Saito et al., 2011
lactose permease	P02920	1-417	peptide-Phe16+Phe-peptide	P		Gly	Leu	Phe	Phe	Phe	Phe	Tyr	Phe	Akiyama & Kanehara, 2004
lactose permease	P02920	1-417	peptide-Phe15+Phe-peptide	P		Phe	Gly	Leu	Phe	Phe	Phe	Phe	Tyr	Akiyama & Kanehara, 2004
sigma-E factor negative regulatory protein	P0AFX7	1-216	peptide-Ala108+Cys-peptide	P		Gly	Val	Ala	Ala	Cys	Val	Ser	Leu	Koide et al., 2008