Substrates for peptidase M41.003: m-AAA peptidase

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
54S ribosomal protein L32, mitochondrial	P25348	1-183	peptide-Leu71+Ala-peptide	P	NT	Gly	Ile	Leu	Leu	Ala	Val	Pro	Lys	Bonn et al., 2011
dynamin-like 120 kDa protein, mitochondrial	O60313	88-960	peptide-Arg194+Ala-peptide	P	NT	Thr	Ala	Phe	Arg	Ala	Thr	Asp	Arg	Ishihara et al., 2006
dynamin-like 120 kDa protein, mitochondrial	O60313	1-960	peptide-Asn87+Phe-peptide	P	NT	Pro	Arg	Arg	Asn	Phe	Trp	Pro	Ala	Ishihara et al., 2006