Substrates for peptidase M23.004: lysostaphin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
Abz-Gly-Gly-Gly-Gly-Gly-EDDnp			Abz-Gly-Gly+Gly-Gly-Gly-EDDnp	S	-	Abz	Gly	Gly	Gly	Gly	Gly	EDD	Warfield et al., 2006
Abz-Gly-Gly-Gly-Gly-Gly-EDDnp			Abz-Gly-Gly-Gly+Gly-Gly-EDDnp	S	Abz	Gly	Gly	Gly	Gly	Gly	EDD	-	Warfield et al., 2006
MV11 FRET substrate (Colicin-E9 Asn43Cys, Ser49Gly, Ser51Ala, Gly52Ala mutant	P09883	1-57	peptide-Gly48+Gly-peptide	S	Trp	Gly	Gly	Gly	Gly	Gly	Ala	Ala	Bardelang et al., 2009
peptidoglycan muropeptide			Lys-gamma-Gly-Gly+Gly-Gly-Gly-Ala	P	Ala	Gln	Lys	Gly	Gly	Gly	Gly	Ala	Xu et al., 1997
peptidoglycan muropeptide			Lys-gamma-Gly-Gly-Gly+Gly-Gly-Ala	P	Gln	Lys	Gly	Gly	Gly	Gly	Ala	-	Xu et al., 1997
peptidoglycan muropeptide			Lys-gamma-Gly-Gly-Gly-Gly+Gly-Ala	P	Lys	Gly	Gly	Gly	Gly	Ala	-	-	Xu et al., 1997