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Literature for peptidase M23.004: lysostaphin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

(Topics flags: A Assay, S Structure, P Specificity, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Antenucci,L., Virtanen,S., Thapa,C., Jartti,M., Pitkanen,I., Tossavainen,H. and Permi,P.
    Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM
    elife (2024) 13 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2023
  2. Charoenjotivadhanakul,S., Sakdee,S., Imtong,C., Li,H.C. and Angsuthanasombat,C.
    Conserved loop residues-Tyr(270) and Asn(372) near the catalytic site of the lysostaphin endopeptidase are essential for staphylolytic activity toward pentaglycine binding and catalysis
    Biochem Biophys Res Commun (2023) 668, 111-117. PubMed  Europe PubMed DOI
  3. Razew,A., Laguri,C., Vallet,A., Bougault,C., Kaus-Drobek,M., Sabala,I. and Simorre,J.P.
    Staphylococcus aureus sacculus mediates activities of M23 hydrolases
    Nat Commun (2023) 14, 6706-6706. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Shestak,N.V., Grishin,A.V., Lyashchuk,A.M., Lunin,V.G. and Karyagina,A.S.
    The choice of chromatographic resin for the purification of recombinant lysostaphin affects its activity
    Protein Expr Purif (2023) 207, 106274-106274. PubMed  Europe PubMed DOI
    5. 2022
  5. Konstantinova,S., Grishin,A., Lyashchuk,A., Vasina,I., Karyagina,A. and Lunin,V.
    Influence of NaCl and pH on lysostaphin catalytic activity, cell binding, and bacteriolytic activity
    Appl Microbiol Biotechnol (2022) 106, 6519-6534. PubMed  Europe PubMed DOI
  6. Siddiqui,F., Ulker,M., Laizure,I.E. and Johnson,K.C.
    Engineered device in E. coli lyses S. aureus at physiological fever temperatures
    MicroPubl Biol (2022) 2022 PubMed  Europe PubMed DOI  PMC  EPMC
  7. Zha,J., Li,J., Su,Z., Akimbekov,N. and Wu,X.
    Lysostaphin: Engineering and Potentiation toward Better Applications
    J Agric Food Chem (2022) 70, 11441-11457. PubMed  Europe PubMed DOI
    8. 2021
  8. Bonar,E., Bukowski,M., Chlebicka,K., Madry,A., Bereznicka,A., Kosecka-Strojek,M., Dubin,G., Miedzobrodzki,J., Mak,P. and Wladyka,B.
    Human skin microbiota-friendly lysostaphin
    Int J Biol Macromol (2021) 183, 852-860. PubMed  Europe PubMed DOI
  9. Duman-Ozdamar,Z.E., Unlu,A., Unal,H., Woodley,J.M. and Bi Nay,B.
    High-yield production of active recombinant S. simulans lysostaphin expressed in E. coli in a laboratory bioreactor
    Protein Expr Purif (2021) 177, 105753-105753. PubMed  Europe PubMed DOI
  10. Ye,G., Huang,J., Li,G., Zhang,J., Sun,Y., Zeng,D., Bao,W., Zhong,J. and Huang,Q.
    Clinical efficacy of intravaginal recombinant lysostaphin administration on endometritis in sows
    Vet Med Sci (2021) 7, 746-754. PubMed  Europe PubMed DOI
    11. 2020
  11. Batool,N., Ko,K.S., Chaurasia,A.K. and Kim,K.K.
    Functional Identification of Serine Hydroxymethyltransferase as a Key Gene Involved in Lysostaphin Resistance and Virulence Potential of Staphylococcus aureus Strains
    Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
  12. Cheleuitte-Nieves,C.E., Diaz,L.L., de la Gandara,M.P., Gonzalez,A., Freiwald,W.A., de Lencastre,H.M., Tomasz,A. and Euler,C.W.
    Evaluation of Topical Lysostaphin as a Novel Treatment for Instrumented Rhesus Macaques (Macaca mulatta) Infected with Methicillin- Resistant Staphylococcus aureus
    Comp Med (2020) PubMed  Europe PubMed DOI
  13. Fang,Y., Kirsch,J.R., Li,L., Brooks,S.A., Heim,S., Tan,C., Eszterhas,S., Cheng,H.D., Zhao,H., Xiong,Y.Q. and Griswold,K.E.
    Deimmunized Lysostaphin Synergizes with Small-molecule Chemotherapies and Re-sensitizes MRSA to beta-Lactam Antibiotics
    Antimicrob Agents Chemother (2020) PubMed  Europe PubMed DOI
  14. Gonzalez-Delgado,L.S., Walters-Morgan,H., Salamaga,B., Robertson,A.J., Hounslow,A.M., Jagielska,E., Sabala,I., Williamson,M.P., Lovering,A.L. and Mesnage,S.
    Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b
    Nat Chem Biol (2020) 16, 24-30. PubMed  Europe PubMed DOI
  15. Grishin,A.V., Konstantinova,S.V., Vasina,I.V., Shestak,N.V., Karyagina,A.S. and Lunin,V.G.
    A Simple Protocol for the Determination of Lysostaphin Enzymatic Activity
    Antibiotics (Basel) (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  16. Jayakumar,J., Kumar,V.A., Biswas,L. and Biswas,R.
    Therapeutic applications of lysostaphin against Staphylococcus aureus
    J Appl Microbiol (2020) PubMed  Europe PubMed DOI  V
  17. Vacek,L., Kobzova,S., Cmelik,R., Pantucek,R. and Janda,L.
    Enzybiotics LYSSTAPH-S and LYSDERM-S as Potential Therapeutic Agents for Chronic MRSA Wound Infections
    Antibiotics (Basel) (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  18. Willing,S., Dyer,E., Schneewind,O. and Missiakas,D.
    FmhA and FmhC of Staphylococcus aureus incorporate serine residues into peptidoglycan crossbridges
    J Biol Chem (2020) 295, 13664-13676. PubMed  Europe PubMed DOI
    19. 2019
  19. Duman,Z.E., Unlu,A., Cakar,M.M., Unal,H. and Binay,B.
    Enhanced production of recombinant Staphylococcus simulans lysostaphin using medium engineering
    Prep Biochem Biotechnol (2019) 49, 521-528. PubMed  Europe PubMed DOI  E
  20. Grishin,A.V., Lavrova,N.V., Lyashchuk,A.M., Strukova,N.V., Generalova,M.S., Ryazanova,A.V., Shestak,N.V., Boksha,I.S., Polyakov,N.B., Galushkina,Z.M., Soboleva,L.A., Vetchinin,S.S., Pavlov,V.M., Karyagina,A.S. and Lunin,V.G.
    The influence of dimerization on the pharmacokinetics and activity of an antibacterial enzyme lysostaphin
    Molecules (2019) 24 PubMed  Europe PubMed DOI
  21. Madry,A., Jendroszek,A., Dubin,G. and Wladyka,B.
    Production of lysostaphin by nonproprietary method utilizing a promoter from toxin-antitoxin system
    Mol Biotechnol (2019) 61, 774-782. PubMed  Europe PubMed DOI  E
  22. Mitkowski,P., Jagielska,E., Nowak,E., Bujnicki,J.M., Stefaniak,F., Niedzialek,D., Bochtler,M. and Sabala,I.
    Structural bases of peptidoglycan recognition by lysostaphin SH3b domain
    Sci Rep (2019) 9, 5965-5965. PubMed  Europe PubMed DOI  PMC  EPMC  S
    23. 2018
  23. Chandra Ojha,S., Imtong,C., Meetum,K., Sakdee,S., Katzenmeier,G. and Angsuthanasombat,C.
    Purification and characterization of the antibacterial peptidase lysostaphin from Staphylococcus simulans: adverse influence of Zn(2+) on bacteriolytic activity
    Protein Expr Purif (2018) 151, 106-112. PubMed  Europe PubMed DOI
  24. Jin,J., Zhou,H., Cui,Z.C., Wang,L., Luo,P.F., Ji,S.Z., Hu,X.Y., Ma,B., Wang,G.Y., Zhu,S.H. and Xia,Z.F.
    [Antiseptic effect of compound lysostaphin disinfectant and its preventive effect on infection of artificial dermis after graft on full-thickness skin defect wound in rats]
    Zhonghua Shao Shang Za Zhi (2018) 34, 225-232. PubMed  Europe PubMed DOI  U
  25. Johnson,C.T., Wroe,J.A., Agarwal,R., Martin,K.E., Guldberg,R.E., Donlan,R.M., Westblade,L.F. and Garcia,A.J.
    Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing
    Proc Natl Acad Sci U S A (2018) 115, E4960-E4960. PubMed  Europe PubMed DOI  U
  26. Raz,A., Serrano,A., Thaker,M., Alston,T. and Fischetti,V.A.
    Lysostaphin lysibody leads to effective opsonization and killing of methicillin resistant Staphylococcus aureus in a murine model
    Antimicrob Agents Chemother (2018) 62, e01056-18-e01056-18. PubMed  Europe PubMed DOI
  27. Tossavainen,H., Raulinaitis,V., Kauppinen,L., Pentikainen,U., Maaheimo,H. and Permi,P.
    Structural and functional insights into lysostaphin-substrate interaction
    Front Mol Biosci (2018) 5, 60-60. PubMed  Europe PubMed DOI  PMC  EPMC  S
    28. 2017
  28. Fernandez,L., Gonzalez,S., Campelo,A.B., Martinez,B., Rodriguez,A. and Garcia,P.
    Downregulation of autolysin-encoding genes by phage-derived lytic proteins inhibits biofilm formation in Staphylococcus aureus
    Antimicrob Agents Chemother (2017) 61, e02724-16-e02724-16. PubMed  Europe PubMed DOI
  29. Hathaway,H., Ajuebor,J., Stephens,L., Coffey,A., Potter,U., Sutton,J.M. and Jenkins,A.T.
    Thermally triggered release of the bacteriophage endolysin CHAPK and the bacteriocin lysostaphin for the control of methicillin resistant Staphylococcus aureus (MRSA)
    J Control Release (2017) 245, 108-115. PubMed  Europe PubMed DOI  U
  30. Lood,R., Molina,H. and Fischetti,V.A.
    Determining bacteriophage endopeptidase activity using either fluorophore-quencher labeled peptides combined with liquid chromatography-mass spectrometry (LC-MS) or Forster resonance energy transfer (FRET) assays
    PLoS ONE (2017) 12, e0173919-e0173919. PubMed  Europe PubMed DOI  A
  31. Raulinaitis,V., Tossavainen,H., Aitio,O., Seppala,R. and Permi,P.
    (1)H (13)C and (15)N resonance assignments of the new lysostaphin family endopeptidase catalytic domain from Staphylococcus aureus
    Biomol NMR Assign (2017) 11, 69-73. PubMed  Europe PubMed DOI
  32. Raulinaitis,V., Tossavainen,H., Aitio,O., Juuti,J.T., Hiramatsu,K., Kontinen,V. and Permi,P.
    Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family
    Sci Rep (2017) 7, 6020-6020. PubMed  Europe PubMed DOI  PMC  EPMC
    33. 2016
  33. Abtahi,H., Farhangnia,L. and Ghaznavi-Rad,E.
    In vitro and in vivo antistaphylococcal activity determination of the new recombinant lysostaphin protein
    Jundishapur J Microbiol (2016) 9, e28489-e28489. PubMed  Europe PubMed DOI  U
  34. Filatova,L.Y., Donovan,D.M., Ishnazarova,N.T., Foster-Frey,J.A., Becker,S.C., Pugachev,V.G., Balabushevich,N.G., Dmitrieva,N.F. and Klyachko,N.L.
    A chimeric LysK-lysostaphin fusion enzyme lysing Staphylococcus aureus cells: a study of both kinetics of inactivation and specifics of interaction with anionic polymers
    Appl Biochem Biotechnol (2016) 180, 544-557. PubMed  Europe PubMed DOI
    35. 2015
  35. Blazanovic,K., Zhao,H., Choi,Y., Li,W., Salvat,R.S., Osipovitch,D.C., Fields,J., Moise,L., Berwin,B.L., Fiering,S.N., Bailey-Kellogg,C. and Griswold,K.E.
    Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance
    Mol Ther Methods Clin Dev (2015) 2, 15021-15021. PubMed  Europe PubMed DOI  PMC  EPMC
    36. 2014
  36. Chen,C., Fan,H., Huang,Y., Peng,F., Fan,H., Yuan,S. and Tong,Y.
    Recombinant lysostaphin protects mice from methicillin-resistant Staphylococcus aureus pneumonia
    Biomed Res Int (2014) 2014, 602185-602185. PubMed  Europe PubMed DOI  PMC  EPMC  U
  37. Farhangnia,L., Ghaznavi-Rad,E., Mollaee,N. and Abtahi,H.
    Cloning, expression, and purification of recombinant lysostaphin from Staphylococcus simulans
    Jundishapur J Microbiol (2014) 7, e10009-e10009. PubMed  Europe PubMed DOI  E
  38. Sabala,I., Jagielska,E., Bardelang,P.T., Czapinska,H., Dahms,S.O., Sharpe,J.A., James,R., Than,M.E., Thomas,N.R. and Bochtler,M.
    Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans
    FEBS J (2014) 281, 4112-4122. PubMed  Europe PubMed DOI  S
  39. Sundarrajan,S., Raghupatil,J., Vipra,A., Narasimhaswamy,N., Saravanan,S., Appaiah,C., Poonacha,N., Desai,S., Nair,S., Bhatt,R.N., Roy,P., Chikkamadaiah,R., Durgaiah,M., Sriram,B., Padmanabhan,S. and Sharma,U.
    Bacteriophage-derived CHAP domain protein, P128, kills Staphylococcus cells by cleaving interpeptide cross-bridge of peptidoglycan
    Microbiology (Reading) (2014) 160, 2157-2169. PubMed  Europe PubMed DOI
  40. Zhao,H., Blazanovic,K., Choi,Y., Bailey-Kellogg,C. and Griswold,K.E.
    Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris
    Appl Environ Microbiol (2014) 80, 2746-2753. PubMed  Europe PubMed DOI  E
    41. 2013
  41. Huang,C.Y., Hsu,J.T., Chung,P.H., Cheng,W.T., Jiang,Y.N. and Ju,Y.T.
    Site-specific N-glycosylation of caprine lysostaphin restricts its bacteriolytic activity toward Staphylococcus aureus
    Anim Biotechnol (2013) 24, 129-147. PubMed  Europe PubMed DOI  E
  42. Lu,H.R., Gu,M.G., Huang,Q., Huang,J.J., Lu,W.Y., Lu,H. and Huang,Q.S.
    Hydrogen/deuterium exchange mass spectrometry and site-directed disulfide cross-linking suggest an important dynamic interface between the two lysostaphin domains
    Antimicrob Agents Chemother (2013) 57, 1872-1881. PubMed  Europe PubMed DOI
    43. 2012
  43. Kokai-Kun,J.F.
    Lysostaphin: a silver bullet for staph
     (2012) , 147-165.
  44. Park,P.W. and Mecham,R.P.
    Lysostaphin
    [ISSN:978-0-12-407743-0] (2012) 3, 1558-1560. DOI
  45. Sabala,I., Jonsson,I.M., Tarkowski,A. and Bochtler,M.
    Anti-staphylococcal activities of lysostaphin and LytM catalytic domain
    BMC Microbiol (2012) 12, 97-97. PubMed  Europe PubMed DOI  PMC  EPMC
    46. 2011
  46. Belyansky,I., Tsirline,V.B., Montero,P.N., Satishkumar,R., Martin,T.R., Lincourt,A.E., Shipp,J.I., Vertegel,A. and Heniford,B.T.
    Lysostaphin-coated mesh prevents staphylococcal infection and significantly improves survival in a contaminated surgical field
    Am Surg (2011) 77, 1025-1031. PubMed  Europe PubMed  U
  47. Belyansky,I., Tsirline,V.B., Martin,T.R., Klima,D.A., Heath,J., Lincourt,A.E., Satishkumar,R., Vertegel,A. and Heniford,B.T.
    The addition of lysostaphin dramatically improves survival, protects porcine biomesh from infection, and improves graft tensile shear strength
    J Surg Res (2011) 171, 409-415. PubMed  Europe PubMed DOI  U
  48. Cui,F., Li,G., Huang,J., Zhang,J., Lu,M., Lu,W., Huan,J. and Huang,Q.
    Development of chitosan-collagen hydrogel incorporated with lysostaphin (CCHL) burn dressing with anti-methicillin-resistant Staphylococcus aureus and promotion wound healing properties
    Drug Deliv (2011) 18, 173-180. PubMed  Europe PubMed DOI  U
    49. 2010
  49. Bastos,M.C.F., Coutinho,B.G. and Coelho,M.L.V.
    Lysostaphin: a staphylococcal bacteriolysin with potential clinical applications
    Pharmaceuticals (2010) 3, 1139-1161. PubMed  Europe PubMed DOI  U
  50. Cui,F., Li,G., Huang,J., Zhang,J., Lu,M., Lu,W. and Huang,Q.
    Extension of nasal anti-Staphylococcus aureus efficacy of lysostaphin by its incorporation into a chitosan-o/w cream
    Drug Deliv (2010) 17, 617-623. PubMed  Europe PubMed DOI  U
  51. Desbois,A.P., Gemmell,C.G. and Coote,P.J.
    In vivo efficacy of the antimicrobial peptide ranalexin in combination with the endopeptidase lysostaphin against wound and systemic meticillin-resistant Staphylococcus aureus (MRSA) infections
    Int J Antimicrob Agents (2010) 35, 559-565. PubMed  Europe PubMed DOI  U
  52. Desbois,A.P., Lang,S., Gemmell,C.G. and Coote,P.J.
    Surface disinfection properties of the combination of an antimicrobial peptide, ranalexin, with an endopeptidase, lysostaphin, against methicillin-resistant Staphylococcus aureus (MRSA)
    J Appl Microbiol (2010) 108, 723-730. PubMed  Europe PubMed DOI  U
  53. Gargis,S.R., Heath,H.E., LeBlanc,P.A., Dekker,L., Simmonds,R.S. and Sloan,G.L.
    Inhibition of the activity of both domains of lysostaphin through peptidoglycan modification by the lysostaphin immunity protein
    Appl Environ Microbiol (2010) 76, 6944-6946. PubMed  Europe PubMed DOI
    54. 2009
  54. Bardelang,P., Vankemmelbeke,M., Zhang,Y., Jarvis,H., Antoniadou,E., Rochette,S., Thomas,N.R., Penfold,C.N. and James,R.
    Design of a polypeptide FRET substrate that facilitates study of the antimicrobial protease lysostaphin
    Biochem J (2009) 418, 615-624. PubMed  Europe PubMed DOI  A
  55. Huang,J., Wu,H., Zhang,J. and Huang,Q.
    [Purification of recombinant lysostaphin by monoclonal antibody affinity chromatography]
    Sheng Wu Gong Cheng Xue Bao (2009) 25, 147-151. PubMed  Europe PubMed DOI
  56. Kokai-Kun,J.F., Chanturiya,T. and Mond,J.J.
    Lysostaphin eradicates established Staphylococcus aureus biofilms in jugular vein catheterized mice
    J Antimicrob Chemother (2009) 64, 94-100. PubMed  Europe PubMed DOI  U
  57. Placencia,F.X., Kong,L. and Weisman,L.E.
    Treatment of methicillin-resistant Staphylococcus aureus in neonatal mice: lysostaphin versus vancomycin
    Pediatr Res (2009) 65, 420-424. PubMed  Europe PubMed DOI  U
    58. 2008
  58. Kumar,J.K.
    Lysostaphin: an antistaphylococcal agent
    Appl Microbiol Biotechnol (2008) 80, 555-561. PubMed  Europe PubMed DOI  V  U
    59. 2007
  59. Graham,S. and Coote,P.J.
    Potent, synergistic inhibition of Staphylococcus aureus upon exposure to a combination of the endopeptidase lysostaphin and the cationic peptide ranalexin
    J Antimicrob Chemother (2007) 59, 759-762. PubMed  Europe PubMed DOI
  60. Kokai-Kun,J.F., Chanturiya,T. and Mond,J.J.
    Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model
    J Antimicrob Chemother (2007) 60, 1051-1059. PubMed  Europe PubMed DOI  U
  61. Oluola,O., Kong,L., Fein,M. and Weisman,L.E.
    Lysostaphin in treatment of neonatal Staphylococcus aureus infection
    Antimicrob Agents Chemother (2007) 51, 2198-2200. PubMed  Europe PubMed DOI  PMC  EPMC  U
  62. Surovtsev,V.I., Borzenkov,V.M., Fedorov,T.V. and Smotrov,O.I.
    Ionogenic groups in the active site of lysostaphin. Kinetic and thermodynamic data compared with x-ray crystallographic data
    Biochemistry (Mosc) (2007) 72, 989-993. PubMed  Europe PubMed DOI
  63. Szweda,P., Kotlowski,R., lacka,I. and Synowiecki,J.
    Protective effect of lysostaphin from Staphylococcus simulans against growth of Staphylococcus aureus in milk and some other food products
    J Food Saf (2007) 27, 265-274. DOI
    64. 2006
  64. Grundling,A. and Schneewind,O.
    Cross-linked peptidoglycan mediates lysostaphin binding to the cell wall envelope of Staphylococcus aureus
    J Bacteriol (2006) 188, 2463-2472. PubMed  Europe PubMed DOI  PMC  EPMC
  65. [YEAR:16-2-2006]Klein,M., Kronke,M. and Krut,O.
    Expression of lysostaphin in HeLa cells protects from host cell killing by intracellular Staphylococcus aureus
    Med Microbiol Immunol (16-2-2006) 195, 159-163. PubMed  Europe PubMed DOI
  66. [YEAR:19-9-2006]Sharma,R., Sharma,P.R., Choudhary,M.L., Pande,A. and Khatri,G.S.
    Cytoplasmic expression of mature glycylglycine endopeptidase lysostaphin with an amino terminal hexa-histidine in a soluble and catalytically active form in Escherichia coli
    Protein Expr Purif (19-9-2006) 45, 206-215. PubMed  Europe PubMed DOI  E
  67. [YEAR:7-10-2006]Warfield,R., Bardelang,P., Saunders,H., Chan,W.C., Penfold,C., James,R. and Thomas,N.R.
    Internally quenched peptides for the study of lysostaphin: an antimicrobial protease that kills Staphylococcus aureus
    Org Biomol Chem (7-10-2006) 4, 3626-3638. PubMed  Europe PubMed DOI  A
    68. 2005
  68. Kusuma,C.M. and Kokai-Kun,J.F.
    Comparison of four methods for determining lysostaphin susceptibility of various strains of Staphylococcus aureus
    Antimicrob Agents Chemother (2005) 49, 3256-3263. PubMed  Europe PubMed DOI  PMC  EPMC
  69. [YEAR:27-5-2005]Mierau,I., Leij,P., van Swam,I., Blommestein,B., Floris,E., Mond,J. and Smid,E.J.
    Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE: the case of lysostaphin
    Microb Cell Fact (27-5-2005) 4, 15-15. PubMed  Europe PubMed DOI  PMC  EPMC  E
    70. 2004
  70. Fan,W., Plaut,K., Bramley,A.J., Barlow,J.W., Mischler,S.A. and Kerr,D.E.
    Persistency of adenoviral-mediated lysostaphin expression in goat mammary glands
    J Dairy Sci (2004) 87, 602-608. PubMed  Europe PubMed DOI
  71. Park,P.W. and Mecham,R.P.
    Lysostaphin
    [ISSN:0-12-079610-4] (2004) 2, 1004-1005.  V
  72. Shah,A., Mond,J. and Walsh,S.
    Lysostaphin-coated catheters eradicate Staphylococccus aureus challenge and block surface colonization
    Antimicrobial Agents Chemother (2004) 48, 2704-2707. PubMed  Europe PubMed DOI  PMC  EPMC
  73. Walsh,S., Kokai-Kun,J., Shah,A. and Mond,J.
    Extended nasal residence time of lysostaphin and an anti-staphylococcal monoclonal antibody by delivery in semisolid or polymeric carriers
    Pharm Res (2004) 21, 1770-1775. PubMed  Europe PubMed DOI
    74. 2003
  74. [YEAR:7-11-2003]Heath Farris,M., Heath,L.S., Heath,H.E., LeBlanc,P.A., Simmonds,R.S. and Sloan,G.L.
    Expression of the genes for lysostaphin and lysostaphin resistance in streptococci
    FEMS Microbiol Lett (7-11-2003) 228, 115-119. PubMed  Europe PubMed DOI
  75. Kokai-Kun,J.F., Walsh,S.M., Chanturiya,T. and Mond,J.J.
    Lysostaphin cream eradicates Staphylococcus aureus nasal colonization in a cotton rat model
    Antimicrobial Agents Chemother (2003) 47, 1589-1597. PubMed  Europe PubMed DOI  PMC  EPMC
  76. Mitra,A., Hruska,K.S., Wellnitz,O., Kerr,D.E., Capuco,A.V. and Wall,R.J.
    Expression of lysostaphin in milk of transgenic mice affects the growth of neonates
    Transgenic Res (2003) 12, 597-605. PubMed  Europe PubMed DOI
  77. von Eiff,C., Kokai-Kun,J.F., Becker,K. and Peters,G.
    In vitro activity of recombinant lysostaphin against Staphylococcus aureus isolates from anterior nares and blood
    Antimicrobial Agents Chemother (2003) 47, 3613-3615. PubMed  Europe PubMed DOI  PMC  EPMC
  78. Walsh,S., Shah,A. and Mond,J.
    Improved pharmacokinetics and reduced antibody reactivity of lysostaphin conjugated to polyethylene glycol
    Antimicrobial Agents Chemother (2003) 47, 554-558. PubMed  Europe PubMed DOI  PMC  EPMC
    79. 2002
  79. Dajcs,J.J., Thibodeaux,B.A., Girgis,D.O., Shaffer,M.D., Delvisco,S.M. and O'Callaghan,R.J.
    Immunity to lysostaphin and its therapeutic value for ocular MRSA infections in the rabbit
    Invest Ophthalmol Vis Sci (2002) 43, 3712-3716. PubMed  Europe PubMed
  80. Kiri,N., Archer,G. and Climo,M.W.
    Combinations of lysostaphin with beta-lactams are synergistic against oxacillin-resistant Staphylococcus epidermidis
    Antimicrobial Agents Chemother (2002) 46, 2017-2020. PubMed  Europe PubMed DOI  PMC  EPMC
    81. 2001
  81. Climo,M.W., Ehlert,K. and Archer,G.L.
    Mechanism and suppression of lysostaphin resistance in oxacillin-resistant Staphylococcus aureus
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