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Literature for peptidase M23.004: lysostaphin

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

(Topics flags: A Assay, S Structure, P Specificity, E Expression, U Therapeutic, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

    2024
  1. Antenucci,L., Virtanen,S., Thapa,C., Jartti,M., Pitkanen,I., Tossavainen,H. and Permi,P.<br>Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM<br>elife (2024) 13 PubMed  Europe PubMed DOI  PMC  EPMC
    2. 2023
  2. Charoenjotivadhanakul,S., Sakdee,S., Imtong,C., Li,H.C. and Angsuthanasombat,C.<br>Conserved loop residues-Tyr(270) and Asn(372) near the catalytic site of the lysostaphin endopeptidase are essential for staphylolytic activity toward pentaglycine binding and catalysis<br>Biochem Biophys Res Commun (2023) 668, 111-117. PubMed  Europe PubMed DOI
  3. Razew,A., Laguri,C., Vallet,A., Bougault,C., Kaus-Drobek,M., Sabala,I. and Simorre,J.P.<br>Staphylococcus aureus sacculus mediates activities of M23 hydrolases<br>Nat Commun (2023) 14, 6706-6706. PubMed  Europe PubMed DOI  PMC  EPMC
  4. Shestak,N.V., Grishin,A.V., Lyashchuk,A.M., Lunin,V.G. and Karyagina,A.S.<br>The choice of chromatographic resin for the purification of recombinant lysostaphin affects its activity<br>Protein Expr Purif (2023) 207, 106274-106274. PubMed  Europe PubMed DOI
    5. 2022
  5. Konstantinova,S., Grishin,A., Lyashchuk,A., Vasina,I., Karyagina,A. and Lunin,V.<br>Influence of NaCl and pH on lysostaphin catalytic activity, cell binding, and bacteriolytic activity<br>Appl Microbiol Biotechnol (2022) 106, 6519-6534. PubMed  Europe PubMed DOI
  6. Siddiqui,F., Ulker,M., Laizure,I.E. and Johnson,K.C.<br>Engineered device in E. coli lyses S. aureus at physiological fever temperatures<br>MicroPubl Biol (2022) 2022 PubMed  Europe PubMed DOI  PMC  EPMC
  7. Zha,J., Li,J., Su,Z., Akimbekov,N. and Wu,X.<br>Lysostaphin: Engineering and Potentiation toward Better Applications<br>J Agric Food Chem (2022) 70, 11441-11457. PubMed  Europe PubMed DOI
    8. 2021
  8. Bonar,E., Bukowski,M., Chlebicka,K., Madry,A., Bereznicka,A., Kosecka-Strojek,M., Dubin,G., Miedzobrodzki,J., Mak,P. and Wladyka,B.<br>Human skin microbiota-friendly lysostaphin<br>Int J Biol Macromol (2021) 183, 852-860. PubMed  Europe PubMed DOI
  9. Duman-Ozdamar,Z.E., Unlu,A., Unal,H., Woodley,J.M. and Bi Nay,B.<br>High-yield production of active recombinant S. simulans lysostaphin expressed in E. coli in a laboratory bioreactor<br>Protein Expr Purif (2021) 177, 105753-105753. PubMed  Europe PubMed DOI
  10. Ye,G., Huang,J., Li,G., Zhang,J., Sun,Y., Zeng,D., Bao,W., Zhong,J. and Huang,Q.<br>Clinical efficacy of intravaginal recombinant lysostaphin administration on endometritis in sows<br>Vet Med Sci (2021) 7, 746-754. PubMed  Europe PubMed DOI
    11. 2020
  11. Batool,N., Ko,K.S., Chaurasia,A.K. and Kim,K.K.<br>Functional Identification of Serine Hydroxymethyltransferase as a Key Gene Involved in Lysostaphin Resistance and Virulence Potential of Staphylococcus aureus Strains<br>Int J Mol Sci (2020) 21 PubMed  Europe PubMed DOI  PMC  EPMC
  12. Cheleuitte-Nieves,C.E., Diaz,L.L., de la Gandara,M.P., Gonzalez,A., Freiwald,W.A., de Lencastre,H.M., Tomasz,A. and Euler,C.W.<br>Evaluation of Topical Lysostaphin as a Novel Treatment for Instrumented Rhesus Macaques (Macaca mulatta) Infected with Methicillin- Resistant Staphylococcus aureus<br>Comp Med (2020) PubMed  Europe PubMed DOI
  13. Fang,Y., Kirsch,J.R., Li,L., Brooks,S.A., Heim,S., Tan,C., Eszterhas,S., Cheng,H.D., Zhao,H., Xiong,Y.Q. and Griswold,K.E.<br>Deimmunized Lysostaphin Synergizes with Small-molecule Chemotherapies and Re-sensitizes MRSA to beta-Lactam Antibiotics<br>Antimicrob Agents Chemother (2020) PubMed  Europe PubMed DOI
  14. Gonzalez-Delgado,L.S., Walters-Morgan,H., Salamaga,B., Robertson,A.J., Hounslow,A.M., Jagielska,E., Sabala,I., Williamson,M.P., Lovering,A.L. and Mesnage,S.<br>Two-site recognition of Staphylococcus aureus peptidoglycan by lysostaphin SH3b<br>Nat Chem Biol (2020) 16, 24-30. PubMed  Europe PubMed DOI
  15. Grishin,A.V., Konstantinova,S.V., Vasina,I.V., Shestak,N.V., Karyagina,A.S. and Lunin,V.G.<br>A Simple Protocol for the Determination of Lysostaphin Enzymatic Activity<br>Antibiotics (Basel) (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  16. Jayakumar,J., Kumar,V.A., Biswas,L. and Biswas,R.<br>Therapeutic applications of lysostaphin against Staphylococcus aureus<br>J Appl Microbiol (2020) PubMed  Europe PubMed DOI  V
  17. Vacek,L., Kobzova,S., Cmelik,R., Pantucek,R. and Janda,L.<br>Enzybiotics LYSSTAPH-S and LYSDERM-S as Potential Therapeutic Agents for Chronic MRSA Wound Infections<br>Antibiotics (Basel) (2020) 9 PubMed  Europe PubMed DOI  PMC  EPMC
  18. Willing,S., Dyer,E., Schneewind,O. and Missiakas,D.<br>FmhA and FmhC of Staphylococcus aureus incorporate serine residues into peptidoglycan crossbridges<br>J Biol Chem (2020) 295, 13664-13676. PubMed  Europe PubMed DOI
    19. 2019
  19. Duman,Z.E., Unlu,A., Cakar,M.M., Unal,H. and Binay,B.<br>Enhanced production of recombinant Staphylococcus simulans lysostaphin using medium engineering<br>Prep Biochem Biotechnol (2019) 49, 521-528. PubMed  Europe PubMed DOI  E
  20. Grishin,A.V., Lavrova,N.V., Lyashchuk,A.M., Strukova,N.V., Generalova,M.S., Ryazanova,A.V., Shestak,N.V., Boksha,I.S., Polyakov,N.B., Galushkina,Z.M., Soboleva,L.A., Vetchinin,S.S., Pavlov,V.M., Karyagina,A.S. and Lunin,V.G.<br>The influence of dimerization on the pharmacokinetics and activity of an antibacterial enzyme lysostaphin<br>Molecules (2019) 24 PubMed  Europe PubMed DOI
  21. Madry,A., Jendroszek,A., Dubin,G. and Wladyka,B.<br>Production of lysostaphin by nonproprietary method utilizing a promoter from toxin-antitoxin system<br>Mol Biotechnol (2019) 61, 774-782. PubMed  Europe PubMed DOI  E
  22. Mitkowski,P., Jagielska,E., Nowak,E., Bujnicki,J.M., Stefaniak,F., Niedzialek,D., Bochtler,M. and Sabala,I.<br>Structural bases of peptidoglycan recognition by lysostaphin SH3b domain<br>Sci Rep (2019) 9, 5965-5965. PubMed  Europe PubMed DOI  PMC  EPMC  S
    23. 2018
  23. Chandra Ojha,S., Imtong,C., Meetum,K., Sakdee,S., Katzenmeier,G. and Angsuthanasombat,C.<br>Purification and characterization of the antibacterial peptidase lysostaphin from Staphylococcus simulans: adverse influence of Zn(2+) on bacteriolytic activity<br>Protein Expr Purif (2018) 151, 106-112. PubMed  Europe PubMed DOI
  24. Jin,J., Zhou,H., Cui,Z.C., Wang,L., Luo,P.F., Ji,S.Z., Hu,X.Y., Ma,B., Wang,G.Y., Zhu,S.H. and Xia,Z.F.<br>[Antiseptic effect of compound lysostaphin disinfectant and its preventive effect on infection of artificial dermis after graft on full-thickness skin defect wound in rats]<br>Zhonghua Shao Shang Za Zhi (2018) 34, 225-232. PubMed  Europe PubMed DOI  U
  25. Johnson,C.T., Wroe,J.A., Agarwal,R., Martin,K.E., Guldberg,R.E., Donlan,R.M., Westblade,L.F. and Garcia,A.J.<br>Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing<br>Proc Natl Acad Sci U S A (2018) 115, E4960-E4960. PubMed  Europe PubMed DOI  U
  26. Raz,A., Serrano,A., Thaker,M., Alston,T. and Fischetti,V.A.<br>Lysostaphin lysibody leads to effective opsonization and killing of methicillin resistant Staphylococcus aureus in a murine model<br>Antimicrob Agents Chemother (2018) 62, e01056-18-e01056-18. PubMed  Europe PubMed DOI
  27. Tossavainen,H., Raulinaitis,V., Kauppinen,L., Pentikainen,U., Maaheimo,H. and Permi,P.<br>Structural and functional insights into lysostaphin-substrate interaction<br>Front Mol Biosci (2018) 5, 60-60. PubMed  Europe PubMed DOI  PMC  EPMC  S
    28. 2017
  28. Fernandez,L., Gonzalez,S., Campelo,A.B., Martinez,B., Rodriguez,A. and Garcia,P.<br>Downregulation of autolysin-encoding genes by phage-derived lytic proteins inhibits biofilm formation in Staphylococcus aureus<br>Antimicrob Agents Chemother (2017) 61, e02724-16-e02724-16. PubMed  Europe PubMed DOI
  29. Hathaway,H., Ajuebor,J., Stephens,L., Coffey,A., Potter,U., Sutton,J.M. and Jenkins,A.T.<br>Thermally triggered release of the bacteriophage endolysin CHAPK and the bacteriocin lysostaphin for the control of methicillin resistant Staphylococcus aureus (MRSA)<br>J Control Release (2017) 245, 108-115. PubMed  Europe PubMed DOI  U
  30. Lood,R., Molina,H. and Fischetti,V.A.<br>Determining bacteriophage endopeptidase activity using either fluorophore-quencher labeled peptides combined with liquid chromatography-mass spectrometry (LC-MS) or Forster resonance energy transfer (FRET) assays<br>PLoS ONE (2017) 12, e0173919-e0173919. PubMed  Europe PubMed DOI  A
  31. Raulinaitis,V., Tossavainen,H., Aitio,O., Seppala,R. and Permi,P.<br>(1)H (13)C and (15)N resonance assignments of the new lysostaphin family endopeptidase catalytic domain from Staphylococcus aureus<br>Biomol NMR Assign (2017) 11, 69-73. PubMed  Europe PubMed DOI
  32. Raulinaitis,V., Tossavainen,H., Aitio,O., Juuti,J.T., Hiramatsu,K., Kontinen,V. and Permi,P.<br>Identification and structural characterization of LytU, a unique peptidoglycan endopeptidase from the lysostaphin family<br>Sci Rep (2017) 7, 6020-6020. PubMed  Europe PubMed DOI  PMC  EPMC
    33. 2016
  33. Abtahi,H., Farhangnia,L. and Ghaznavi-Rad,E.<br>In vitro and in vivo antistaphylococcal activity determination of the new recombinant lysostaphin protein<br>Jundishapur J Microbiol (2016) 9, e28489-e28489. PubMed  Europe PubMed DOI  U
  34. Filatova,L.Y., Donovan,D.M., Ishnazarova,N.T., Foster-Frey,J.A., Becker,S.C., Pugachev,V.G., Balabushevich,N.G., Dmitrieva,N.F. and Klyachko,N.L.<br>A chimeric LysK-lysostaphin fusion enzyme lysing Staphylococcus aureus cells: a study of both kinetics of inactivation and specifics of interaction with anionic polymers<br>Appl Biochem Biotechnol (2016) 180, 544-557. PubMed  Europe PubMed DOI
    35. 2015
  35. Blazanovic,K., Zhao,H., Choi,Y., Li,W., Salvat,R.S., Osipovitch,D.C., Fields,J., Moise,L., Berwin,B.L., Fiering,S.N., Bailey-Kellogg,C. and Griswold,K.E.<br>Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance<br>Mol Ther Methods Clin Dev (2015) 2, 15021-15021. PubMed  Europe PubMed DOI  PMC  EPMC
    36. 2014
  36. Chen,C., Fan,H., Huang,Y., Peng,F., Fan,H., Yuan,S. and Tong,Y.<br>Recombinant lysostaphin protects mice from methicillin-resistant Staphylococcus aureus pneumonia<br>Biomed Res Int (2014) 2014, 602185-602185. PubMed  Europe PubMed DOI  PMC  EPMC  U
  37. Farhangnia,L., Ghaznavi-Rad,E., Mollaee,N. and Abtahi,H.<br>Cloning, expression, and purification of recombinant lysostaphin from Staphylococcus simulans<br>Jundishapur J Microbiol (2014) 7, e10009-e10009. PubMed  Europe PubMed DOI  E
  38. Sabala,I., Jagielska,E., Bardelang,P.T., Czapinska,H., Dahms,S.O., Sharpe,J.A., James,R., Than,M.E., Thomas,N.R. and Bochtler,M.<br>Crystal structure of the antimicrobial peptidase lysostaphin from Staphylococcus simulans<br>FEBS J (2014) 281, 4112-4122. PubMed  Europe PubMed DOI  S
  39. Sundarrajan,S., Raghupatil,J., Vipra,A., Narasimhaswamy,N., Saravanan,S., Appaiah,C., Poonacha,N., Desai,S., Nair,S., Bhatt,R.N., Roy,P., Chikkamadaiah,R., Durgaiah,M., Sriram,B., Padmanabhan,S. and Sharma,U.<br>Bacteriophage-derived CHAP domain protein, P128, kills Staphylococcus cells by cleaving interpeptide cross-bridge of peptidoglycan<br>Microbiology (Reading) (2014) 160, 2157-2169. PubMed  Europe PubMed DOI
  40. Zhao,H., Blazanovic,K., Choi,Y., Bailey-Kellogg,C. and Griswold,K.E.<br>Gene and protein sequence optimization for high-level production of fully active and aglycosylated lysostaphin in Pichia pastoris<br>Appl Environ Microbiol (2014) 80, 2746-2753. PubMed  Europe PubMed DOI  E
    41. 2013
  41. Huang,C.Y., Hsu,J.T., Chung,P.H., Cheng,W.T., Jiang,Y.N. and Ju,Y.T.<br>Site-specific N-glycosylation of caprine lysostaphin restricts its bacteriolytic activity toward Staphylococcus aureus<br>Anim Biotechnol (2013) 24, 129-147. PubMed  Europe PubMed DOI  E
  42. Lu,H.R., Gu,M.G., Huang,Q., Huang,J.J., Lu,W.Y., Lu,H. and Huang,Q.S.<br>Hydrogen/deuterium exchange mass spectrometry and site-directed disulfide cross-linking suggest an important dynamic interface between the two lysostaphin domains<br>Antimicrob Agents Chemother (2013) 57, 1872-1881. PubMed  Europe PubMed DOI
    43. 2012
  43. Kokai-Kun,J.F.<br>Lysostaphin: a silver bullet for staph<br> (2012) , 147-165.
  44. Park,P.W. and Mecham,R.P.<br>Lysostaphin<br>[ISSN:978-0-12-407743-0] (2012) 3, 1558-1560. DOI
  45. Sabala,I., Jonsson,I.M., Tarkowski,A. and Bochtler,M.<br>Anti-staphylococcal activities of lysostaphin and LytM catalytic domain<br>BMC Microbiol (2012) 12, 97-97. PubMed  Europe PubMed DOI  PMC  EPMC
    46. 2011
  46. Belyansky,I., Tsirline,V.B., Montero,P.N., Satishkumar,R., Martin,T.R., Lincourt,A.E., Shipp,J.I., Vertegel,A. and Heniford,B.T.<br>Lysostaphin-coated mesh prevents staphylococcal infection and significantly improves survival in a contaminated surgical field<br>Am Surg (2011) 77, 1025-1031. PubMed  Europe PubMed  U
  47. Belyansky,I., Tsirline,V.B., Martin,T.R., Klima,D.A., Heath,J., Lincourt,A.E., Satishkumar,R., Vertegel,A. and Heniford,B.T.<br>The addition of lysostaphin dramatically improves survival, protects porcine biomesh from infection, and improves graft tensile shear strength<br>J Surg Res (2011) 171, 409-415. PubMed  Europe PubMed DOI  U
  48. Cui,F., Li,G., Huang,J., Zhang,J., Lu,M., Lu,W., Huan,J. and Huang,Q.<br>Development of chitosan-collagen hydrogel incorporated with lysostaphin (CCHL) burn dressing with anti-methicillin-resistant Staphylococcus aureus and promotion wound healing properties<br>Drug Deliv (2011) 18, 173-180. PubMed  Europe PubMed DOI  U
    49. 2010
  49. Bastos,M.C.F., Coutinho,B.G. and Coelho,M.L.V.<br>Lysostaphin: a staphylococcal bacteriolysin with potential clinical applications<br>Pharmaceuticals (2010) 3, 1139-1161. PubMed  Europe PubMed DOI  U
  50. Cui,F., Li,G., Huang,J., Zhang,J., Lu,M., Lu,W. and Huang,Q.<br>Extension of nasal anti-Staphylococcus aureus efficacy of lysostaphin by its incorporation into a chitosan-o/w cream<br>Drug Deliv (2010) 17, 617-623. PubMed  Europe PubMed DOI  U
  51. Desbois,A.P., Gemmell,C.G. and Coote,P.J.<br>In vivo efficacy of the antimicrobial peptide ranalexin in combination with the endopeptidase lysostaphin against wound and systemic meticillin-resistant Staphylococcus aureus (MRSA) infections<br>Int J Antimicrob Agents (2010) 35, 559-565. PubMed  Europe PubMed DOI  U
  52. Desbois,A.P., Lang,S., Gemmell,C.G. and Coote,P.J.<br>Surface disinfection properties of the combination of an antimicrobial peptide, ranalexin, with an endopeptidase, lysostaphin, against methicillin-resistant Staphylococcus aureus (MRSA)<br>J Appl Microbiol (2010) 108, 723-730. PubMed  Europe PubMed DOI  U
  53. Gargis,S.R., Heath,H.E., LeBlanc,P.A., Dekker,L., Simmonds,R.S. and Sloan,G.L.<br>Inhibition of the activity of both domains of lysostaphin through peptidoglycan modification by the lysostaphin immunity protein<br>Appl Environ Microbiol (2010) 76, 6944-6946. PubMed  Europe PubMed DOI
    54. 2009
  54. Bardelang,P., Vankemmelbeke,M., Zhang,Y., Jarvis,H., Antoniadou,E., Rochette,S., Thomas,N.R., Penfold,C.N. and James,R.<br>Design of a polypeptide FRET substrate that facilitates study of the antimicrobial protease lysostaphin<br>Biochem J (2009) 418, 615-624. PubMed  Europe PubMed DOI  A
  55. Huang,J., Wu,H., Zhang,J. and Huang,Q.<br>[Purification of recombinant lysostaphin by monoclonal antibody affinity chromatography]<br>Sheng Wu Gong Cheng Xue Bao (2009) 25, 147-151. PubMed  Europe PubMed DOI
  56. Kokai-Kun,J.F., Chanturiya,T. and Mond,J.J.<br>Lysostaphin eradicates established Staphylococcus aureus biofilms in jugular vein catheterized mice<br>J Antimicrob Chemother (2009) 64, 94-100. PubMed  Europe PubMed DOI  U
  57. Placencia,F.X., Kong,L. and Weisman,L.E.<br>Treatment of methicillin-resistant Staphylococcus aureus in neonatal mice: lysostaphin versus vancomycin<br>Pediatr Res (2009) 65, 420-424. PubMed  Europe PubMed DOI  U
    58. 2008
  58. Kumar,J.K.<br>Lysostaphin: an antistaphylococcal agent<br>Appl Microbiol Biotechnol (2008) 80, 555-561. PubMed  Europe PubMed DOI  V  U
    59. 2007
  59. Graham,S. and Coote,P.J.<br>Potent, synergistic inhibition of Staphylococcus aureus upon exposure to a combination of the endopeptidase lysostaphin and the cationic peptide ranalexin<br>J Antimicrob Chemother (2007) 59, 759-762. PubMed  Europe PubMed DOI
  60. Kokai-Kun,J.F., Chanturiya,T. and Mond,J.J.<br>Lysostaphin as a treatment for systemic Staphylococcus aureus infection in a mouse model<br>J Antimicrob Chemother (2007) 60, 1051-1059. PubMed  Europe PubMed DOI  U
  61. Oluola,O., Kong,L., Fein,M. and Weisman,L.E.<br>Lysostaphin in treatment of neonatal Staphylococcus aureus infection<br>Antimicrob Agents Chemother (2007) 51, 2198-2200. PubMed  Europe PubMed DOI  PMC  EPMC  U
  62. Surovtsev,V.I., Borzenkov,V.M., Fedorov,T.V. and Smotrov,O.I.<br>Ionogenic groups in the active site of lysostaphin. Kinetic and thermodynamic data compared with x-ray crystallographic data<br>Biochemistry (Mosc) (2007) 72, 989-993. PubMed  Europe PubMed DOI
  63. Szweda,P., Kotlowski,R., lacka,I. and Synowiecki,J.<br>Protective effect of lysostaphin from Staphylococcus simulans against growth of Staphylococcus aureus in milk and some other food products<br>J Food Saf (2007) 27, 265-274. DOI
    64. 2006
  64. Grundling,A. and Schneewind,O.<br>Cross-linked peptidoglycan mediates lysostaphin binding to the cell wall envelope of Staphylococcus aureus<br>J Bacteriol (2006) 188, 2463-2472. PubMed  Europe PubMed DOI  PMC  EPMC
  65. [YEAR:16-2-2006]Klein,M., Kronke,M. and Krut,O.<br>Expression of lysostaphin in HeLa cells protects from host cell killing by intracellular Staphylococcus aureus<br>Med Microbiol Immunol (16-2-2006) 195, 159-163. PubMed  Europe PubMed DOI
  66. [YEAR:19-9-2006]Sharma,R., Sharma,P.R., Choudhary,M.L., Pande,A. and Khatri,G.S.<br>Cytoplasmic expression of mature glycylglycine endopeptidase lysostaphin with an amino terminal hexa-histidine in a soluble and catalytically active form in Escherichia coli<br>Protein Expr Purif (19-9-2006) 45, 206-215. PubMed  Europe PubMed DOI  E
  67. [YEAR:7-10-2006]Warfield,R., Bardelang,P., Saunders,H., Chan,W.C., Penfold,C., James,R. and Thomas,N.R.<br>Internally quenched peptides for the study of lysostaphin: an antimicrobial protease that kills Staphylococcus aureus<br>Org Biomol Chem (7-10-2006) 4, 3626-3638. PubMed  Europe PubMed DOI  A
    68. 2005
  68. Kusuma,C.M. and Kokai-Kun,J.F.<br>Comparison of four methods for determining lysostaphin susceptibility of various strains of Staphylococcus aureus<br>Antimicrob Agents Chemother (2005) 49, 3256-3263. PubMed  Europe PubMed DOI  PMC  EPMC
  69. [YEAR:27-5-2005]Mierau,I., Leij,P., van Swam,I., Blommestein,B., Floris,E., Mond,J. and Smid,E.J.<br>Industrial-scale production and purification of a heterologous protein in Lactococcus lactis using the nisin-controlled gene expression system NICE: the case of lysostaphin<br>Microb Cell Fact (27-5-2005) 4, 15-15. PubMed  Europe PubMed DOI  PMC  EPMC  E
    70. 2004
  70. Fan,W., Plaut,K., Bramley,A.J., Barlow,J.W., Mischler,S.A. and Kerr,D.E.<br>Persistency of adenoviral-mediated lysostaphin expression in goat mammary glands<br>J Dairy Sci (2004) 87, 602-608. PubMed  Europe PubMed DOI
  71. Park,P.W. and Mecham,R.P.<br>Lysostaphin<br>[ISSN:0-12-079610-4] (2004) 2, 1004-1005.  V
  72. Shah,A., Mond,J. and Walsh,S.<br>Lysostaphin-coated catheters eradicate Staphylococccus aureus challenge and block surface colonization<br>Antimicrobial Agents Chemother (2004) 48, 2704-2707. PubMed  Europe PubMed DOI  PMC  EPMC
  73. Walsh,S., Kokai-Kun,J., Shah,A. and Mond,J.<br>Extended nasal residence time of lysostaphin and an anti-staphylococcal monoclonal antibody by delivery in semisolid or polymeric carriers<br>Pharm Res (2004) 21, 1770-1775. PubMed  Europe PubMed DOI
    74. 2003
  74. [YEAR:7-11-2003]Heath Farris,M., Heath,L.S., Heath,H.E., LeBlanc,P.A., Simmonds,R.S. and Sloan,G.L.<br>Expression of the genes for lysostaphin and lysostaphin resistance in streptococci<br>FEMS Microbiol Lett (7-11-2003) 228, 115-119. PubMed  Europe PubMed DOI
  75. Kokai-Kun,J.F., Walsh,S.M., Chanturiya,T. and Mond,J.J.<br>Lysostaphin cream eradicates Staphylococcus aureus nasal colonization in a cotton rat model<br>Antimicrobial Agents Chemother (2003) 47, 1589-1597. PubMed  Europe PubMed DOI  PMC  EPMC
  76. Mitra,A., Hruska,K.S., Wellnitz,O., Kerr,D.E., Capuco,A.V. and Wall,R.J.<br>Expression of lysostaphin in milk of transgenic mice affects the growth of neonates<br>Transgenic Res (2003) 12, 597-605. PubMed  Europe PubMed DOI
  77. von Eiff,C., Kokai-Kun,J.F., Becker,K. and Peters,G.<br>In vitro activity of recombinant lysostaphin against Staphylococcus aureus isolates from anterior nares and blood<br>Antimicrobial Agents Chemother (2003) 47, 3613-3615. PubMed  Europe PubMed DOI  PMC  EPMC
  78. Walsh,S., Shah,A. and Mond,J.<br>Improved pharmacokinetics and reduced antibody reactivity of lysostaphin conjugated to polyethylene glycol<br>Antimicrobial Agents Chemother (2003) 47, 554-558. PubMed  Europe PubMed DOI  PMC  EPMC
    79. 2002
  79. Dajcs,J.J., Thibodeaux,B.A., Girgis,D.O., Shaffer,M.D., Delvisco,S.M. and O'Callaghan,R.J.<br>Immunity to lysostaphin and its therapeutic value for ocular MRSA infections in the rabbit<br>Invest Ophthalmol Vis Sci (2002) 43, 3712-3716. PubMed  Europe PubMed
  80. Kiri,N., Archer,G. and Climo,M.W.<br>Combinations of lysostaphin with beta-lactams are synergistic against oxacillin-resistant Staphylococcus epidermidis<br>Antimicrobial Agents Chemother (2002) 46, 2017-2020. PubMed  Europe PubMed DOI  PMC  EPMC
    81. 2001
  81. Climo,M.W., Ehlert,K. and Archer,G.L.<br>Mechanism and suppression of lysostaphin resistance in oxacillin-resistant Staphylococcus aureus<br>Antimicrobial Agents Chemother (2001) 45, 1431-1437. PubMed  Europe PubMed DOI  PMC  EPMC
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