Substrates for peptidase M16.019: YMXG peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
coenzyme PQQ synthesis protein A	Q49148	2-29	peptide-Ser9+Glu-peptide	P	MS	Pro	Ile	Val	Ser	Glu	Ile	Cys	Val	Martins et al., 2019
coenzyme PQQ synthesis protein A	Q49148	2-29	peptide-Ser19+Tyr-peptide	P	MS	Glu	Val	Thr	Ser	Tyr	Glu	Ser	Ala	Martins et al., 2019
coenzyme PQQ synthesis protein A	Q49148	2-29	peptide-Glu21+Ser-peptide	P	MS	Thr	Ser	Tyr	Glu	Ser	Ala	Glu	Ile	Martins et al., 2019
coenzyme PQQ synthesis protein A	Q49148	2-29	peptide-Thr18+Ser-peptide	P	MS	Met	Glu	Val	Thr	Ser	Tyr	Glu	Ser	Martins et al., 2019
coenzyme PQQ synthesis protein A Cys12Ser mutant			peptide-Ser12+Val-peptide	N		Ser	Glu	Ile	Ser	Val	Gly	Met	Glu	Martins et al., 2019