Substrates for peptidase M16.004: chloroplast (stromal) processing peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
ATP synthase subunit beta, mitochondrial	P23704	1-519	Peptide-Ala28+Ala-Peptide	P	NT	Val	Arg	Pro	Ala	Ala	Leu	Asn	Leu	Bassham et al., 1994
ATP synthase subunit beta, mitochondrial	P23704	1-519	Peptide-Pro35+Ala-Peptide	P	NT	Leu	Arg	Ala	Pro	Ala	Leu	Ser	Arg	Bassham et al., 1994
chlorophyll a-b binding protein 6A, chloroplast precursor	P12360	1-246	peptide-Met40+Ser-peptide	P		Thr	Asn	Phe	Met	Ser	Arg	Phe	Ser	Richter & Lamppa, 1998
chlorophyll a-b binding protein, chloroplast precursor	P04784	35-266	peptide-Lys40+Ala-peptide	P		Thr	Ala	Ala	Lys	Ala	Lys	Gln	Val	Richter & Lamppa, 1998
consensus cleavage			(Val/Ile)-Xaa-(Ala/Cys)+Ala	N		-	Val	Xaa	Ala	Ala	-	-	-	Lamppa, 2004
oxygen-evolving enhancer 1	Q7X9V5	18-301	peptide-Val28+Asn-peptide	P	CS	Pro	Ser	Met	Val	Asn	Gly	Lys	Gln	Chaal et al., 2003
oxygen-evolving enhancer protein 1, chloroplast precursor	P27665	1-325	peptide-Arg31+Ala-peptide	P		His	Val	Ala	Arg	Ala	Phe	Gly	Val	Richter & Lamppa, 1998
oxygen-evolving enhancer protein 1, chloroplastic	P12853	1-291	peptide-Ala15+Ala-peptide	P	CS	Gly	Val	Arg	Ala	Ala	Arg	Pro	Asn	Chaal et al., 2003
oxygen-evolving enhancer protein 1, chloroplastic	Q9SBN6	1-293	peptide-Ala15+Ala-peptide	P	CS	Val	Ser	Arg	Ala	Ala	Arg	Pro	Val	Chaal et al., 2003
oxygen-evolving enhancer protein 1, chloroplastic	P12359	1-332	peptide-Lys33+Ala-peptide	P	CS	Asn	Val	Cys	Lys	Ala	Phe	Gly	Val	Chaal et al., 2003
oxygen-evolving enhancer protein 1, chloroplastic	P14226	1-329	peptide-Lys32+Ala-peptide	P	CS	Ser	Val	Ser	Lys	Ala	Phe	Gly	Leu	Chaal et al., 2003
oxygen-evolving enhancer protein 2, chloroplast precursor	Q00434	1-258	peptide-Lys34+Ala-peptide	P		Phe	Val	Cys	Lys	Ala	Gln	Lys	Asn	Richter & Lamppa, 1998
Peptidyl-prolyl cis-trans isomerase, mitochondrial	P10255-1	45-223	Peptide-Phe31+Ser-Peptide	P	NT	Thr	Ala	Thr	Phe	Ser	Cys	Ala	Arg	Bassham et al., 1994
plastid oxygen-evolving enhancer 1	Q5I4B6	1-332	peptide-Met43+Thr-peptide	P	CS	Pro	Pro	Arg	Met	Thr	Ser	Ala	Gly	Chaal et al., 2003
plastocyanin, chloroplastic, precursor	P07030	1-165	peptide-Lys41+Ala-peptide	P		Met	Ser	Ile	Lys	Ala	Ser	Leu	Lys	Richter & Lamppa, 1998
protein TOC75, chloroplastic	Q43715	1-809	peptide-Cys35+His-peptide	P	NT	Ser	Leu	Lys	Cys	His	Leu	Ser	Pro	Tranel & Keegstra, 1996
protein TOC75-3, chloroplastic	Q9STE8	1-818	peptide-Val79+Ala-peptide	P	NT	Pro	Leu	Ala	Val	Ala	Ser	Val	Ser	Inoue et al., 2005
ribulose bisphosphate carboxylase small chain 1, chloroplast precursor	P00873	1-185	peptide-Gln45+Met-peptide	P		Gln	Ala	Asn	Gln	Met	Met	Val	Trp	Creighton et al., 1993
ribulose bisphosphate carboxylase/oxygenase activase, chloroplast precursor	P10871	1-472	peptide-Lys57+Ala-peptide	P		Met	Thr	Val	Lys	Ala	Ala	Glu	Asn	Richter & Lamppa, 1998