$VAR1 = undef;

Summary for peptidase M16.004: chloroplast (stromal) processing peptidase

Names
MEROPS Name	chloroplast (stromal) processing peptidase
Other names	chloroplast processing endopeptidase, stromal processing peptidase

Domain architecture

MEROPS Classification
Classification	Clan ME >> Subclan (none) >> Family M16 >> Subfamily B >> M16.004
Holotype	chloroplast (stromal) processing peptidase (Pisum sativum) (peptidase unit: 197-432), MERNUM MER0002008
History	Identifier created: Handbook of Proteolytic Enzymes (1998) Academic Press, London.

Activity
Catalytic type	Metallo
NC-IUBMB	Not yet included in IUBMB recommendations.
Physiology	Cleaves transit peptide during import of proteins to the chloroplast.
Cleavage site specificity	Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage pattern	-/v/-/kaA/-/-/- (based on 19 cleavages)

Specificity matrix

Amino acid	P4	P3	P2	P1	P1'	P2'	P3'	P4'
Gly	1	0	0	0	0	1	3	1
Pro	3	1	1	1	0	0	2	1
Ala	0	3	4	4	13	1	2	0
Val	2	6	1	2	0	0	2	4
Leu	1	2	0	0	0	3	1	2
Ile	0	0	1	0	0	0	0	0
Met	2	0	1	2	1	1	0	0
Phe	1	0	1	1	0	3	1	0
Tyr	0	0	0	0	0	0	0	0
Trp	0	0	0	0	0	0	0	1
Ser	2	3	1	0	2	3	2	2
Thr	3	1	1	0	1	0	0	0
Cys	0	0	2	1	0	1	0	0
Asn	1	1	1	0	1	0	1	3
Gln	1	0	0	1	0	1	1	1
Asp	0	0	0	0	0	0	0	0
Glu	0	0	0	0	0	0	1	0
Lys	0	0	1	6	0	1	2	1
Arg	0	2	3	1	0	3	0	2
His	1	0	0	0	1	0	0	0