Substrates for peptidase M12.345: moojeni peptidase A

Summary Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala+Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Val Glu Ala Leu Tyr Leu Val Reichl & Mandelbaum, 1993
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser+His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Cya Gly Ser His Leu Val Glu Reichl & Mandelbaum, 1993
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr+Leu-Val-Cya-Gly-Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Glu Ala Leu Tyr Leu Val Cya Gly Reichl & Mandelbaum, 1993
insulin B-chain (oxidized) P01317 25-54 Phe-Val-Asn-Gln-His-Leu-Cya-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-Tyr-Leu-Val-Cya-Gly+Glu-Arg-Gly-Phe-Phe-Tyr-Thr-Pro-Lys-Ala N Leu Val Cya Gly Glu Arg Gly Phe Reichl & Mandelbaum, 1993
plasminogen P00747 20-810 peptide-Ala459+Ser-peptide P NT Gly Thr Glu Ala Ser Val Val Ala Ho et al., 2001
Plasminogen P00747 20-810 Peptide-Cys103+Lys-Peptide P NT Leu Ser Glu Cys Lys Thr Gly Asn Ho et al., 2002
Plasminogen P00747 20-810 Peptide-Glu78+Asn-Peptide P NT Ile Met Ala Glu Asn Arg Lys Ser Ho et al., 2002
Plasminogen P00747 20-810 Peptide-Val92+Leu-Peptide P NT Arg Asp Val Val Leu Phe Glu Lys Ho et al., 2002
Plasminogen P00747 20-810 Peptide-Arg87+Met-Peptide P NT Ile Ile Ile Arg Met Arg Asp Val Ho et al., 2002
Plasminogen P00747 20-810 Peptide-Lys96+Lys-Peptide P NT Leu Phe Glu Lys Lys Val Tyr Leu Ho et al., 2002