Substrates for peptidase M12.007: choriolysin H

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
egg envelope protein ZP2	Q9PWC8	25-405	peptide-Ser47+Asp-peptide	P	NT	Val	Gln	Gln	Ser	Asp	Tyr	Leu	Ile	Sano et al., 2008
egg envelope protein ZP2	Q9PWC8	25-405	peptide-Arg66+Val-peptide	P	NT	Leu	Pro	Val	Arg	Val	Glu	Glu	Val	Sano et al., 2008
egg envelope protein ZP2	Q9PWC8	25-405	peptide-Lys73+Ala-peptide	P	NT	Val	Val	Val	Lys	Ala	Gly	Pro	Val	Sano et al., 2008
egg envelope protein ZP3	Q9PWC7	22-431	peptide-Gln67+Ala-peptide	P	NT	Lys	Pro	Val	Gln	Ala	Pro	Leu	Asp	Sano et al., 2008
egg envelope protein ZP3	Q9PWC7	22-431	peptide-Gln79+Ala-peptide	P	NT	Leu	Met	Leu	Gln	Ala	Pro	Glu	Pro	Sano et al., 2008
egg envelope protein ZP3	Q9PWC7	22-431	peptide-Lys105+Gln-peptide	P	NT	Phe	Gln	Leu	Lys	Gln	Pro	Ala	Ser	Sano et al., 2008
Suc-Leu-Leu-Val-Tyr-NHMec			Suc-Leu-Leu-Val-Tyr+NHMec	S		Leu	Leu	Val	Tyr	AMC	-	-	-