Substrates for peptidase M02.005: peptidyl-dipeptidase A (Theromyzon-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Ac-Ser-Asp-Lys-Pro Ac-Ser-Asp+Lys-Pro S - Ac Ser Asp Lys Pro - - Rivière et al., 2004
angiotensin-1 P01019 34-43 Asp-Arg-Val-Tyr-Ile-His-Pro-Phe+His-Leu P Ile His Pro Phe His Leu - - Laurent & Salzet, 1996
hippuryl-His-Leu hippuryl+His-Leu S - - - Hip His Leu - - Rivière et al., 2004
[D-Ala2,Leu5]-enkephalin Tyr-D-Ala-Gly+Phe-Leu S - Tyr DAl Gly Phe Leu - - Laurent & Salzet, 1996