Substrates for peptidase M01.029: M1 aminopeptidase (Plasmodium spp.)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
Arg-NHMec Arg+NHMec S - - - Arg AMC - - - Allary et al., 2002
Asn-NHMec Asn+NHMec S - - - Asn AMC - - - Allary et al., 2002
Leu-NHMec Leu+NHMec S - - - Leu AMC - - - Allary et al., 2002
Lys-NHMec Lys+NHMec S - - - Lys AMC - - - Allary et al., 2002
Phe-NHMec Phe+NHMec S - - - Phe AMC - - - Allary et al., 2002
Ser-NHMec Ser+NHMec S - - - Ser AMC - - - Allary et al., 2002
Tyr-NHMec Tyr+NHMec S - - - Tyr AMC - - - Allary et al., 2002