Substrates for peptidase C63.001: African swine fever virus processing peptidase

Summary Alignment Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
polyprotein pp220	Q08358	2-2475	peptide-Gly44+Gly-peptide	N		Phe	Asn	Gly	Gly	Gly	Asp	Lys	Asn	Andres et al., 2001	16392
polyprotein pp220	Q08358	2-2475	peptide-Gly893+Ala-peptide	N		Ile	Leu	Gly	Gly	Ala	Asp	Glu	Leu	Andres et al., 2001	16393
polyprotein pp220	Q08358	2-2475	peptide-Gly368+Asp-peptide	N		Lys	Lys	Gly	Gly	Asp	Glu	Glu	Lys	Andres et al., 2001	16397
polyprotein pp220	Q08358	2-2475	peptide-Gly522+Ala-peptide	P		Arg	Val	Gly	Gly	Ala	Ala	Leu	Thr	Andres et al., 2001	16395
pp46 polyprotein (African swine fever virus)	Q65179	2-530	peptide-Gly463+Asn-peptide	P		Lys	Val	Gly	Gly	Asn	Glu	Thr	Gln	Andres et al., 2001	16394
pp62 polyprotein	Q65179	2-530	peptide-Gly158+Gly-peptide	N		Lys	Glu	Gly	Gly	Gly	Asn	Asp	Pro	Andres et al., 2001	16396
ras GTPase-activating protein-binding protein 1	Q13283	1-466	peptide-Gly140+Phe-peptide	P	NT	Val	Phe	Gly	Gly	Phe	Val	Thr	Glu