Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q13283

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-466	P		NT	<%Agarwal et al., 2012[]%>
23	cathepsin L	18-32	N		MS	Biniossek et al., 2011
24	cathepsin L	18-32	N		MS	Biniossek et al., 2011
229	trypsin 1	2-466	N		MS	Schilling & Overall, 2008
237	matrix metallopeptidase-2	229-247	N		MS	Schilling & Overall, 2008
247	trypsin 1	2-466	N		MS	Schilling & Overall, 2008
249	chymotrypsin A (cattle-type)	2-466	N		MS	Schilling & Overall, 2008
268	cathepsin L	258-276	N		MS	Biniossek et al., 2011
268	cathepsin S	258-276	N		MS	Biniossek et al., 2011
320	trypsin 1	2-466	N		MS	Schilling & Overall, 2008
331	trypsin 1	2-466	N		MS	Schilling & Overall, 2008
376	trypsin 1	2-466	N		MS	Schilling & Overall, 2008
381	cathepsin L	377-393	N		MS	Biniossek et al., 2011
381	cathepsin S	377-393	N		MS	Biniossek et al., 2011
381	cathepsin B	377-393	N		MS	Biniossek et al., 2011
393	trypsin 1	2-466	N		MS	Schilling & Overall, 2008