Substrates for peptidase C60.006: sortase A (Streptococcus-type)

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
2,3-cyclic-nucleotide 2-phosphodiesterase Q6HTQ7 1-780 peptide-Thr750+Gly-peptide P CS Leu Pro Lys Thr Gly Thr Asn Val Gaspar et al., 2005
Abz-Leu-Pro-Ala-Thr-Gly-Dpn Abz-Leu-Pro-Ala-Thr+Gly-Dpn S Leu Pro Ala Thr Gly Dpn - - Gaspar et al., 2005
Abz-Leu-Pro-Asn-Thr-Ala-Dpn Abz-Leu-Pro-Asn-Thr+Ala-Dpn S Leu Pro Asn Thr Ala Dpn - - Gaspar et al., 2005
Abz-Leu-Pro-Glu-Thr-Gly-Dpn Abz-Leu-Pro-Glu-Thr+Gly-Dpn S Leu Pro Glu Thr Gly Dpn - - Gaspar et al., 2005
cell wall surface anchor family protein Q81XH9 1-627 peptide-Thr594+Gly-peptide P CS Leu Pro Ala Thr Gly Gly Val Ser Gaspar et al., 2005
collagen adhesion protein, C-terminal Q6HQE2 1-882 peptide-Thr851+Gly-peptide P CS Leu Pro Asn Thr Gly His Lys Asn Gaspar et al., 2005
LPXTG-motif cell wall anchor domain protein Q81UJ7 1-969 peptide-Thr941+Gly-peptide P CS Leu Pro Ala Thr Gly His Asp Met Gaspar et al., 2005
LPXTG-motif cell wall anchor domain protein Q6HWB0 1-605 peptide-Thr575+Gly-peptide P CS Leu Pro Lys Thr Gly Ala Ser Ser Gaspar et al., 2005
LPXTG-motif cell wall anchor domain protein Q81NE9 1-372 peptide-Ala339+Gly-peptide P CS Leu Pro Asn Ala Gly Ser Lys Gln Gaspar et al., 2005