Substrates for peptidase C48.008: SENP5 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
ac-Gln-Thr-Gly-Gly-amino-trifluoromethylcoumarin			ac-Gln-Thr-Gly-Gly+amino-trifluoromethylcoumarin	S		Gln	Thr	Gly	Gly	AFC	-	-	-	Drag et al., 2008
Boc-Gln-Thr-Gly-Gly-amino-trifluoromethylcoumarin			Boc-Gln-Thr-Gly-Gly+amino-trifluoromethylcoumarin	S		Gln	Thr	Gly	Gly	AFC	-	-	-	Drag et al., 2008
PolySUMO2/SUMO3	P61956		peptide-Gly93+Lys11-peptide	N		Gln	Thr	Gly	Gly	Lys	Thr	Glu	Asn	Mendes et al., 2015
small ubiquitin-related modifier 2 precursor	P61956	1-95	peptide-Gly93+Val-Tyr	P	AB	Gln	Thr	Gly	Gly	Val	Tyr	-	-	Gong & Yeh, 2006
small ubiquitin-related modifier 3 precursor	P55854	1-103	peptide-Gly92+Val-peptide	P	MU	Gln	Thr	Gly	Gly	Val	Pro	Glu	Ser	Gong & Yeh, 2006
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys532-peptide	P		Gln	Thr	Gly	Gly	Lys	Ser	Ser	Lys	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys535-peptide	P		Gln	Thr	Gly	Gly	Lys	Val	Pro	Ser	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys558-peptide	P		Gln	Thr	Gly	Gly	Lys	Leu	Ile	Gln	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys568-peptide	P		Gln	Thr	Gly	Gly	Lys	Asn	Val	Ala	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys594-peptide	P		Gln	Thr	Gly	Gly	Lys	Thr	Ser	Lys	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys597-peptide	P		Gln	Thr	Gly	Gly	Lys	Ala	Glu	Glu	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys606-peptide	P		Gln	Thr	Gly	Gly	Lys	Ser	Lys	Pro	Zunino et al., 2009
sumoylated dynamin-1-like protein	P63165/O00429	2-97	peptide-Gly97+Lys608-peptide	P		Gln	Thr	Gly	Gly	Lys	Pro	Ile	Pro	Zunino et al., 2009