Substrates for peptidase C46.001: hedgehog protein

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
hedgehog protein precursor Q02936 35-471 peptide-Gly257+Cys-peptide P His Val His Gly Cys Phe Thr Pro Lee et al., 1995 16356
hedgehog protein precursor Q02936 35-471 peptide-Thr326+Pro-peptide N Leu Thr Val Thr Pro Ala His Leu Lee et al., 1995 16357