Substrates for peptidase C19.017: ubiquitin-specific peptidase 9X

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
polyubiquitinated MAP/microtubule affinity-regulating kinase 4	P0CG47/Q96L34	1-76	peptide-Gly76+Lys29-peptide	P		Leu	Arg	Gly	Gly	Lys	Ile	Gln	Asp	Al-Hakim et al., 2008
polyubiquitinated MAP/microtubule affinity-regulating kinase 4	P0CG47/Q96L34	1-76	peptide-Gly76+Lys33-peptide	P		Leu	Arg	Gly	Gly	Lys	Glu	Gly	Ile	Al-Hakim et al., 2008
polyubiquitinated NUAK family SNF1-like kinase 1	P0CG47/O60285	1-76	peptide-Gly76+Lys29-peptide	P		Leu	Arg	Gly	Gly	Lys	Ile	Gln	Asp	Al-Hakim et al., 2008
polyubiquitinated NUAK family SNF1-like kinase 1	P0CG47/O60285	1-76	peptide-Gly76+Lys33-peptide	P		Leu	Arg	Gly	Gly	Lys	Glu	Gly	Ile	Al-Hakim et al., 2008
Ubiquitin-aNH-MHISPPEPESEEEEEHYC	P0CG47	1-76	peptide-Gly76+Met-peptide	N		Leu	Arg	Gly	Gly	Met	His	Ile	Ser	Taya et al., 1998
Ubiquitinated SMAD4	P0CG47/Q13485	1-76/1-552	peptide-Gly76+Lys519-peptide	P	AB	Leu	Arg	Gly	Gly	Lys	Glu	Thr	Pro	Dupont et al., 2009